Search results for "Odds"
showing 10 items of 1327 documents
Airway obstruction in relation to symptoms in chronic respiratory disease—a nationally representative population study
2000
Abstract We examined the severity of airway obstruction and the occurrence of respiratory symptoms in a large, nationally representative population sample and in a subgroup of subjects with chronic bronchitis and/or emphysema to obtain information for developing national prevention and treatment strategies for these diseases. The study population comprised of 7217 randomly selected subjects (aged 30 years and older) who participated in a comprehensive health examination survey. The ‘cases' were subjects diagnosed as having chronic bronchitis and/or emphysema. The survey methods comprised of questionnaires, interviews, physical measurements, including spirometry, and clinical examinations. I…
Prenatal exposure to phenols and lung function, wheeze, and asthma in school-age children from 8 European birth cohorts
2019
Prenatal exposure to phenolic compounds, widely used in many consumer products, can alter lung development and increase the risk of respiratory disorders in the offspring. However, evidence is scarce and mostly focused on bisphenol-A (BPA), although there are other substitutes that could also interfere with the developing respiratory system. We aim to estimate the association between exposure to 5 phenols during pregnancy (BPA, BPAF, BPB, BPF, and BPS) and lung function, wheeze, and asthma in school-age children. We included 2685 mother-child pairs from 8 European birth cohorts. Phenols concentrations were determined in urinary maternal samples collected during pregnancy (1999-2010). Betwee…
Bayesian joint ordinal and survival modeling for breast cancer risk assessment
2016
We propose a joint model to analyze the structure and intensity of the association between longitudinal measurements of an ordinal marker and time to a relevant event. The longitudinal process is defined in terms of a proportional-odds cumulative logit model. Time-to-event is modeled through a left-truncated proportionalhazards model, which incorporates information of the longitudinal marker as well as baseline covariates. Both longitudinal and survival processes are connected by means of a common vector of random effects. General inferences are discussed under the Bayesian approach and include the posterior distribution of the probabilities associated to each longitudinal category and the …
Subject-specific odds ratios in binomial GLMMs with continuous response
2007
In a regression context, the dichotomization of a continuous outcome variable is often motivated by the need to express results in terms of the odds ratio, as a measure of association between the response and one or more risk factors. Starting from the recent work of Moser and Coombs (Odds ratios for a continuous outcome variable without dichotomizing, Statistics in Medicine, 2004, 23, 1843-1860), in this article we explore in a mixed model framework the possibility of obtaining odds ratio estimates from a regression linear model without the need of dichotomizing the response variable. It is shown that the odds ratio estimators derived from a linear mixed model outperform those from a binom…
Regression models for multivariate ordered responses via the Plackett distribution
2008
AbstractWe investigate the properties of a class of discrete multivariate distributions whose univariate marginals have ordered categories, all the bivariate marginals, like in the Plackett distribution, have log-odds ratios which do not depend on cut points and all higher-order interactions are constrained to 0. We show that this class of distributions may be interpreted as a discretized version of a multivariate continuous distribution having univariate logistic marginals. Convenient features of this class relative to the class of ordered probit models (the discretized version of the multivariate normal) are highlighted. Relevant properties of this distribution like quadratic log-linear e…
Flexible latent trait aggregation to analyze employability after the Ph.D. in Italy
2015
The analysis of satisfaction, employability and economic perspectives after the Ph.D. in Italy has not received adequate attention in the past, especially in terms of comparison among universities. To analyze these aspects, in this paper we consider data from the survey ‘Statistica in TEma di Laureati e LAvoro’ on doctors who achieved the title on 2007, 2008 and 2009 [CILEA, Laureati STELLA, indagine occupazionale post-dottorato, dottori di ricerca 2007–2008, Tech. Rep., CILEA, Segrate, 2010; CILEA,Laureati STELLA, indagine occupazionale post-dottorato, dottori di ricerca 2008–2009, Tech. Rep., CILEA, Segrate, 2011]. To deal with the complex, multidimensional nature of the concept, we propo…
Crowdfunding as a tool to support sustainability‐oriented initiatives: Preliminary insights into the role of product/service attributes
2019
A common goal of current research seems to uncover whether crowdfunding (CF) could be considered an effective way to support sustainability-oriented initiatives in securing funding, due to diverging results emerging from literature. We claim that the objective of proving whether CF may benefit sustainability-oriented initiatives could be misplaced; rather, we deem more fruitful to understand how critical are some attributes of products/services pursued within CF campaigns to benefiting sustainability-oriented initiatives and increasing their odds of success in CF. We focus on food-related projects as in this sector, sustainability issues apply more than to any other human activities and con…
The cumulative effect of multiple dimensions of lifestyle on risky drinking during the Covid-19 pandemic
2021
Lifestyle impacts morbidity and mortality worldwide. Herein, we evaluated the association of a multidimensional lifestyle measure and its domains (diet/nutrition, substance use, physical activity, social, stress management, sleep, environmental exposure) with risky drinking. Also, we analyzed the cumulative effect of unhealthy domains in the likelihood of presenting risky drinking. To reach these objectives, data from a web survey conducted in Brazil and Spain was analyzed. The main outcome was risky drinking assessed by the AUDIT-C. Lifestyle was measured using the Short Multidimensional Inventory Lifestyle Evaluation (SMILE). Fixed logistic models were used to evaluate associations betwee…
Lipid-Altering Efficacy of Ezetimibe/Simvastatin 10/20 mg Compared to Rosuvastatin 10 mg in High-Risk Patients with and without Type 2 Diabetes Melli…
2010
AIMS: This post hoc analysis compared the effects of switching to ezetimibe/simvastatin 10/20 mg (EZE/SIMVA) or rosuvastatin 10 mg (ROSUVA) in uncontrolled high-risk hypercholesterolemic patients with/without type 2 diabetes mellitus (T2DM) despite statin monotherapy. METHODS: Patients (n = 618) at high risk for coronary vascular disease with elevated LDL-C ≥100 and ≤190 mg/dL despite use of statins were randomized 1:1 to double-blind EZE/SIMVA 10/20 mg or ROSUVA 10 mg for 6 weeks. Patients were classified as having T2DM based on ≥1 of the following: diagnosis of T2DM, antidiabetic medication, or FPG ≥126 mg/dL. This analysis evaluated percent changes from baseline in lipids among patients …
Pharmacological Neuroenhancement, Perceived Stress, and Resilience in Spine Surgeons–A Cross-Sectional Survey
2022
Background Spine surgeons are usually exposed to high workload and demanding work conditions. Although the relationship between pharmacological neuroenhancement (PNE) and resilience (i.e., the ability to recover from stress), as well as perceived stress and resilience-enhancing factors, has been investigated in the general population, less is known about the impact of those factors in spine surgeons. This study aimed to close that gap by investigating the relationship between PNE use and resilience, perceived stress, or resilience-enhancing factors in spine surgeons. Methods We conducted a cross-sectional survey in a sample of 582 spine surgeons in German-speaking countries (Austria, German…