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showing 10 items of 2973 documents

Protein expression in submandibular glands of young rats is modified by a high-fat/high-sugar maternal diet

2018

International audience; OBJECTIVE: Maternal diet has consequences on many organs of the offspring, but salivary glands have received little attention despite the importance of the saliva secretory function in oral health and control of food intake. The objective of this work was therefore to document in rats the impact of maternal high-fat/high-sugar diet (Western Diet) on submandibular glands of the progeny. DESIGN: Sprague-Dawley rat dams were fed either a Western diet or control diet during gestation and lactation and their pups were sacrificed 25 days after birth. The pups' submandibular gland protein content was characterized by means of 2D-electrophoresis followed by LC-MS/MS. Data we…

Male0301 basic medicinemedicine.medical_specialtySalivaOffspringsalivary glandsproteomeSubmandibular Glandannexin a5BiologyRats Sprague-Dawley03 medical and health scienceschemistry.chemical_compoundPregnancyHeat shock proteinInternal medicineLactationmedicineAnimalsSalivary Proteins and PeptidesGeneral Dentistry2. Zero hungerimmunohistologyCell BiologyGeneral MedicineGlutathioneImmunohistochemistrySubmandibular glandwestern dietRatsOxidative Stress030104 developmental biologyEndocrinologymedicine.anatomical_structureOtorhinolaryngologychemistryDiet WesternPrenatal Exposure Delayed EffectsGestationFemaleAnnexin A5[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition
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A brief online transdiagnostic measure: Psychometric properties of the Overall Anxiety Severity and Impairment Scale (OASIS) among Spanish patients w…

2018

The Overall Anxiety Severity and Impairment Scale (OASIS) is a self-report questionnaire designed to evaluate the severity and functional impairment associated with anxiety. Given its transdiagnostic nature, it can be used indistinctly across anxiety and depressive disorders. In this study, the psychometric properties of the online version of the OASIS were evaluated in a Spanish clinical sample with emotional disorders. Patients (n = 583) with anxiety (n = 250) and depression (n = 333) with a mean age of 37.21 (SD = 12.22), underwent a diagnostic interview and questionnaires assessing anxiety, depression, positive and negative affect, and quality of life. Factorial structure, internal cons…

Male050103 clinical psychologyPsychometricsEmotionsSocial Scienceslcsh:MedicineTest validityAnxietySeverity of Illness Index0302 clinical medicineQuality of lifeMedicine and Health SciencesCutoffPsychologyDiagnosis Computer-AssistedComputer Networkslcsh:ScienceMultidisciplinaryDepression05 social sciencesMiddle AgedAnxiety DisordersConfirmatory factor analysisAnxietyFemalemedicine.symptomPsychologyClinical psychologyResearch ArticleAdultComputer and Information SciencesAdolescentPsychometricsNeuropsychiatric DisordersNeurosesSensitivity and Specificity03 medical and health sciencesYoung AdultRating scaleDiagnostic MedicineMental Health and PsychiatrymedicineHumans0501 psychology and cognitive sciencesAgedPsychiatric Status Rating ScalesDepressive DisorderInternetMood Disorderslcsh:RDiscriminant validityBiology and Life Sciences030227 psychiatryHealth CareSpainQuality of Lifelcsh:QFactor Analysis StatisticalPLoS ONE
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Episodic future thinking together with observational learning benefits prospective memory in high-functioning Korsakoff's syndrome patients

2020

Contains fulltext : 219555.pdf (Publisher’s version ) (Open Access) Objective: Patients with Korsakoff's syndrome (KS) have difficulty carrying out tasks which rely on prospective memory (PM). Since remembering to carry out an action in the future is crucial for living independently, it is of primary interest to develop strategies that improve PM performance in KS patients. Design: The study employed a computer categorization task as an ongoing activity into which a PM task was embedded. We included episodic future thinking (EFT) and observational learning (Experiment 2) to boost PM. Methods: Experiment 1 evaluated the efficacy of EFT following written PM task instructions in ten KS patient…

Male050103 clinical psychologymedicine.medical_specialtyAlzheimer`s disease Donders Center for Medical Neuroscience [Radboudumc 1]Memory Episodicprospective memoryalcoholicsAlcohol use disorderAudiologyTask (project management)All institutes and research themes of the Radboud University Medical CenterProspective memorymedicineHumansObservational learning0501 psychology and cognitive sciencesProspective StudiesCognitive skillMemory Disordersfuture thinkingNeuro- en revalidatiepsychologieRecall05 social sciencesNeuropsychology and rehabilitation psychologyOriginal ArticlesGeneral MedicineMiddle AgedKorsakoff’s syndromemedicine.diseasefuture event stimulationClinical PsychologyKorsakoff Syndromeobservational learningCategorizationFemaleOriginal ArticleKorsakoff's syndromePsychology
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Relations among Romantic Myths, Offline Dating Violence Victimization and Cyber Dating Violence Victimization in Adolescents.

2020

Cyber dating violence is an increasing problem with serious negative consequences for adolescents. Further knowledge about related variables is necessary to develop preventive strategies. The aim of this study was to analyze the correlations among cyber dating violence victimization (cyber-control and cyber-aggression), offline dating violence victimization (physical, verbal&ndash

MaleAdolescentHealth Toxicology and MutagenesiseducationPoison controllcsh:MedicineIntimate Partner Violence050109 social psychologyAdolescentsSuicide preventionOccupational safety and healthArticleDevelopmental psychologycyber dating violenceromantic mythsInjury preventionGender analysisHumans0501 psychology and cognitive sciencesInterpersonal Relationsadolescentsoffline dating violenceComputingMilieux_MISCELLANEOUShealth care economics and organizationsCrime VictimsInternetgender analysis05 social scienceslcsh:RvictimizationPublic Health Environmental and Occupational HealthHuman factors and ergonomicsBullyingMythologysocial sciencesRomancehumanitiesAggressionAdolescent Behaviorbehavior and behavior mechanismsComputingMilieux_COMPUTERSANDSOCIETYFemaleViolència juvenilPsychology050104 developmental & child psychologyInternational journal of environmental research and public health
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The impact of diet during adolescence on the neonatal health of offspring: evidence on the importance of preconception diet. The HUNT study

2020

Background: Emerging evidence suggests that parents' nutritional status before and at the time of conception influences the lifelong physical and mental health of their child. Yet little is known about the relationship between diet in adolescence and the health of the next generation at birth. This study examined data from Norwegian cohorts to assess the relationship between dietary patterns in adolescence and neonatal outcomes. Methods: Data from adolescents who participated in the Nord-TrA¸ndelag Health Study (Young-HUNT) were merged with birth data for their offspring through the Medical Birth Registry of Norway (MBRN). Young-HUNT1 collected data from 8980 adolescents between 1995 and 19…

MaleAdolescentOffspringDeclarationMedicine (miscellaneous)030209 endocrinology & metabolismNorwegianHelsinki declaration03 medical and health sciences0302 clinical medicineEnvironmental healthHunt studyFood choiceneonatal outcomesFood QualityMedicineHumansInfant Health030212 general & internal medicineNeonatal healthadolescentsResearch ethicsbusiness.industrypreconceptionNorwayHUNT studyMental healthlanguage.human_languagenutritionNeonatal outcomesAdolescent BehaviorCohortlanguageFemalePreconception CarebusinessDemography
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The Prevalence of sexual abuse in institutions : Results from a representative population-based sample in Germany

2018

The lifetime prevalence of sexual abuse in institutional settings in Germany was examined in a sample representative of the general adult population (N = 2,437). Participants completed a survey on whether they had ever experienced such abuse, its nature (contact, noncontact, forced sexual, intercourse), the type of institution (e.g. school, club), and the relationship of perpetrator to victim (peer, caregiver, staff member). Overall, 3.1% of adult respondents (women: 4.8%, men: 0.8%) reported having experienced some type of sexual abuse in institutions. Adult women reported higher rates of all types than did men, with rates of 3.9% versus 0.8% for contact sexual abuse, 1.2% versus 0.3% for …

MaleAdolescentSexueller MissbrauchPopulationAdult populationKindsexual offenderPeer GroupChild sexual abuse; GermanyAdult womenddc:150GermanyPrevalenceHumans0501 psychology and cognitive sciencesddc:610educationChildDeutschlandGeneral Psychology0505 lawChild Institutionalizededucation.field_of_studyOrganizationsSchoolsDDC 150 / PsychologySex offenses05 social sciencesPopulation based sampleChild abuse SexualPsychiatry and Mental healthSexual intercourseSexual abuseChild sexual abuse050501 criminologyvictimFemaleClubPsychologyDDC 610 / Medicine & health050104 developmental & child psychologyDemography
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An aggression machine I. The intensity of aggressive defence aroused by aggressive offence

1973

PitkAnen, L. An aggression machine. I. The intensity of aggressive defence aroused by aggressive offence. Scand. J. Psychol., 1973, 14, 56–64.-Sixty 9-year-old boys were tested with an aggression machine (PAM) designed by the writer. PAM allows the variation of both S (light) and R (pressing a button) intensities. The stimuli and responses were given the designations of offensive and defensive aggression, respectively. The following main hypotheses were supported: (1) The intensity of impulsive aggressive defence to an aggressive offence was adapted to the intensity of attack. (2) The intensity of aggressive defence was determined by the authority of the attacker, the defence being stronges…

MaleAggressionOffensiveGeneral MedicineAggressionSocial PerceptionArts and Humanities (miscellaneous)Impulsive BehaviorDevelopmental and Educational PsychologymedicineHumansDefensive aggressionInterpersonal Relationsmedicine.symptomChildPsychologySocial psychologyGeneral PsychologyScandinavian Journal of Psychology
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Intraocular Pressure Telemetry for Managing Glaucoma during the COVID-19 Pandemic

2021

Purpose To evaluate in glaucoma patients the feasibility and use of remote monitoring of intraocular pressure (IOP) with an implanted telemetry sensor during the coronavirus disease 2019 (COVID-19) lockdown. Design Cross-sectional study. Participants Patients previously implanted with a telemetric IOP sensor (Eyemate; Implandata GmbH) were included. Methods Intraocular pressure measurements acquired by the patients during the lockdown were collected by physicians who were located remotely. A questionnaire was sent to 10 participating study centers to evaluate the clinical impact of remote monitoring of IOP via the IOP sensor system. Main Outcome Measures Number of patients who obtained home…

MaleAgingIntraocular pressuregenetic structuresCross-sectional studyIntraocular pressureOffice visitsGlaucomaComorbidityNeurodegenerative01 natural sciences0302 clinical medicineTelemetryTelemetryProspective StudiesProspective cohort studyCOVID-19 coronavirus disease 2019Sensor systemInfectiousGeneral MedicineEquipment DesignMiddle AgedFemaleSwitzerlandmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)MonitoringClinical Trials and Supportive ActivitiesBioengineeringTonometry03 medical and health sciencesTonometry OcularDisease TransmissionClinical ResearchOcularOphthalmologyLockdownmedicineDisease Transmission InfectiousHumans0101 mathematicsEye Disease and Disorders of VisionPandemicsbusiness.industrySARS-CoV-2IOP010102 general mathematicsNeurosciencesCOVID-19Glaucomamedicine.diseaseIOP intraocular pressureeye diseasesFull-length articles and Review articlesUnited KingdomCross-Sectional Studies030221 ophthalmology & optometrysense organsbusinessFollow-Up StudiesOphthalmology. Glaucoma
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Sicilian centenarian offspring are more resistant to immune ageing

2018

Background: Immunosenescence constitutes a major indirect cause of morbidity and mortality in the elderly. Previous analysis of immune signatures in a cohort of centenarian offspring showed an intermediate immunophenotype between age-matched and younger controls. Aims: To confirm and extend the previous studies performing further phenotypical analysis in centenarian offspring and controls. Methods: Analysis of Treg cells, γδ T cells, mucosal-associated invariant T cells, and senescent immune T cells was performed in centenarian offspring and controls. Results: We report significant differences between elderly and centenarian offspring in most of the studied subsets, showing that centenarian…

MaleAgingOffspringImmunosenescenceLongevityBiology03 medical and health sciences0302 clinical medicineImmunophenotypingImmune systemT-Lymphocyte SubsetsHumans030212 general & internal medicineCentenarianFlow cytometrySicilyAgedAged 80 and overInflammationSettore MED/04 - Patologia GeneraleImmunity CellularCase-control studyImmunosenescenceImmune senescenceMiddle AgedAgeingAgeingCase-Control StudiesCohortImmunologyAdult ChildrenFemaleCentenarianGeriatrics and Gerontology030217 neurology & neurosurgery
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Parental effects on offspring longevity--evidence from 17th to 19th century reproductive histories.

2004

Family studies provide support for a modest genetic influence on offspring life span, although the magnitude of these correlations is small.The study aimed to clarify the relative contributions of parental age at birth and overall parental longevity on offspring lifespan, and to identify the biological and cultural mechanisms.Information was derived from two village genealogies (1650-1927) encompassing 9979 births (5315 males, 4664 females). Data selection was guided by the inclusion of information about parental age at birth and lifespan, offspring lifespan and cohort-specific life expectancy.Parental age at reproduction displayed a negative association with offspring survivability, which …

MaleAgingPhysiologyEpidemiologyOffspringmedia_common.quotation_subjectLongevityNegative associationBiologyHistory 18th CenturyPaternal AgeCohort StudiesHistory 17th CenturyGermanyGeneticsHumansParental investmentReproductive Historymedia_commonGeneticsPublic Health Environmental and Occupational HealthLongevityHistory 19th CenturyHistory 20th CenturyFemaleParent–offspring conflictReproductionReproductive HistoriesData selectionDemographyMaternal AgeAnnals of human biology
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