Search results for "Omega-3 fatty acids"

showing 3 items of 13 documents

Clinical and Molecular-Genetic Insights into the Role of Oxidative Stress in Diabetic Retinopathy: Antioxidant Strategies and Future Avenues

2020

Reactive oxygen species (ROS) overproduction and ROS-signaling pathways activation attack the eyes. We evaluated the oxidative stress (OS) and the effects of a daily, core nutritional supplement regimen containing antioxidants and omega 3 fatty acids (A/ω3) in type 2 diabetics (T2DM). A case-control study was carried out in 480 participants [287 T2DM patients with (+)/without (−) diabetic retinopathy (DR) and 193 healthy controls (CG)], randomly assigned to a daily pill of A/ω3. Periodic evaluation through 38 months allowed to outline patient characteristics, DR features, and classic/OS blood parameters. Statistics were performed by the SPSS 24.0 program. Diabetics displayed significantly h…

medicine.medical_specialtyAntioxidanttype 2 diabetes mellitusPhysiologyThiobarbituric acidmedicine.medical_treatmentClinical BiochemistryDietética y nutrición030209 endocrinology & metabolismmedicine.disease_causeBiochemistryArticle03 medical and health scienceschemistry.chemical_compound0302 clinical medicineprevention of blindnessInternal medicineretinopathymedicineTBARSoxidative stressMolecular Biologyomega-3 fatty acidsVitamin Cbusiness.industrylcsh:RM1-950Cell BiologyDiabetic retinopathymedicine.diseaseMalondialdehydeAnatomía ocularlcsh:Therapeutics. PharmacologyantioxidantsEndocrinologychemistrycandidate biomarkers030221 ophthalmology & optometryOftalmologíabusinessOxidative stressRetinopathy
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Do nutritional supplements have a role in age macular degeneration prevention?

2013

Purpose. To review the proposed pathogenic mechanisms of age macular degeneration (AMD), as well as the role of antioxidants (AOX) and omega-3 fatty acids (ω-3) supplements in AMD prevention.Materials and Methods. Current knowledge on the cellular/molecular mechanisms of AMD and the epidemiologic/experimental studies on the effects of AOX andω-3 were addressed all together with the scientific evidence and the personal opinion of professionals involved in the Retina Group of the OFTARED (Spain).Results. High dietary intakes ofω-3 and macular pigments lutein/zeaxanthin are associated with lower risk of prevalence and incidence in AMD. The Age-Related Eye Disease study (AREDS) showed a benefic…

medicine.medical_specialtyLuteineicosapentaenoic acidgenetic structuresmedicine.medical_treatmentSuplements nutritiusPhysiologypigment epithelial-celllsReview ArticleLower riskAntioxidantsclinical-trialchemistry.chemical_compoundlcsh:Ophthalmologybeta-CaroteneOPHTHALMOLOGYOmega-3 fatty acidsMedicineoxidative stressbusiness.industryVitamin Evitamin-EPreventionblue mountains eyeMacular degenerationMicronutrientmedicine.diseaseDietary supplementsEicosapentaenoic acidbeaver dam eyeAge macular degeneration (AMD)Retinal diseaseseye diseasesSurgeryZeaxanthinOphthalmologybeta-caroteneMalalties de la retinachemistrylcsh:RE1-994fatty-acid compositionsense organsbusinessgrowth-factor VEGFJournal of ophthalmology
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Fatty acid composition as biomarkers of freshwater microalgae: analysis of 37 strains of microalgae in 22 genera and in seven classes

2013

The fatty acid (FA) composition of algae is an important determinant of their food quality for consumers, and FAs can also be used as biomarkers for biochemical and energetic pathways in food webs. FA analyses of 7 freshwater algal classes and 37 strains showed clear similarity within classes and strong differences amongst classes. Class was a dominant factor (66.4%) explaining variation in FA signatures of microalgae. The 7 algal classes comprised 4 separate groups according to their FA profiles: (1) Chlorophyceae and Trebouxiophyceae, (2) Bacillariophyceae, (3) Cryptophyceae, Chrysophyceae, and Raphidophyceae, and (4) Euglenophyceae. Each group had a characteristic FA composition, althoug…

ravinnonlaatuChlorophyceaeomega-3 rasvahapotAquatic SciencelipiditZooplanktonAlgaeviherlevätBotanyOmega-3 fatty acidspiilevätLacustrine food webjärviravintoketjuEcology Evolution Behavior and Systematicsnielulevätchemistry.chemical_classificationbiologyTrebouxiophyceaeta1182Fatty acidbiology.organism_classificationFood webchemistryDocosahexaenoic acidCryptomonadsta1181Green algaeDiet quality
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