Search results for "On demand"
showing 8 items of 38 documents
Ionic Liquids on Demand in Continuous Flow
2009
We report on the development of an alternative protocol for the facile, solvent-free synthesis of various novel imidazolium-based ionic liquids (ILs) that affords highly pure products without the necessity of subsequent purification steps. The continuous approach is based on the combination of HPLC pumps with a micromixer and a capillary residence tube. Our system provides a high degree of control over the alkylation reactions due to a high surface-to-volume ratio and superior heat and mass transport. Within the scope of our studies, we focused on ionic liquids containing differently substituted phenyl rings and characterized these compounds with respect to further use for direct applicatio…
Streaming era digital media piracy : an integration of three theoretical perspectives
2018
Consumer digital piracy in media contexts is one of the most publicized adverse developments brought on by the Internet and digitization of data. Since the turn of the millennium, it has irrevocably changed the business environment for the creative industries. The sharp decrease of recorded music sales, especially in the physical album format, is perhaps the best example of the negative effects digital piracy. However, the growth of legal services in digital music and video is balancing this trend, as consumers have found that piracy is no longer the obvious solution to acquiring music and video content. This also calls for new approaches to piracy research. We sought them by integrating th…
SURVEY ON THE DEMAND OF SICILIAN PHYSICIANS FOR A SPECIFIC TRAINING ON HUMAN CADAVERS AND ANIMALS
2018
Currently, surgical training of physicians in Italy has limited possibilities.Surgical training can be performed on dissection of human bodies as well as in animal laboratories, but experience is very poor. We conducted a survey through an anonymous questionnaire in order to evaluate the opinions of post-graduate physicians on their need for experience training on both human and animal bodies during their medical studies. A total of 165 young Sicilian physicians responded to the survey. Only 14 of them (8.5%) declared they had specific training on a live animal, while 46 (27.9%) reported they already attended cadaver labs. Over 70% assigned the maximum score to the utility of such courses a…
The possibilities of energy storage in bulk materials
2018
The increased demand for energy from renewable sources entails the development of storage systems. The purpose of these systems is to supply energy on demand during periods which may not be concurrent with the time of the most efficient production of this energy. Various systems are being developed for storing energy in various forms and over various lengths of time.This paper presents selected projects and the results of studies into thermal energy storage. The results of the present author's own research into the transport of thermal energy in granular beds are also presented. The curves of temperature distribution have been determined; they are essential for the design of the thermal sto…
Evaluation of the inverse electron demand Diels-Alder reaction in rats using a scandium-44-labelled tetrazine for pretargeted PET imaging
2019
Background Pretargeted imaging allows the use of short-lived radionuclides when imaging the accumulation of slow clearing targeting agents such as antibodies. The biotin-(strept)avidin and the bispecific antibody-hapten interactions have been applied in clinical pretargeting studies; unfortunately, these systems led to immunogenic responses in patients. The inverse electron demand Diels-Alder (IEDDA) reaction between a radiolabelled tetrazine (Tz) and a trans-cyclooctene (TCO)-functionalized targeting vector is a promising alternative for clinical pretargeted imaging due to its fast reaction kinetics. This strategy was first applied in nuclear medicine using an 111In-labelled Tz to image TC…
Significance of I313V mutation of NLPR3 gene in two pediatric patients
2011
Results Both case #1 (M.T) and #2 (V.C) displayed a mild clinical phenotype (episodes of urticarial rash and arthralgia associated with elevation of acute phase reactants), compatible with FCAS and Muckle-Wells syndrome, respectively. Both patients displayed good response to NSAID and/or steroid on demand. Compared to HD controls, patients displayed enhanced and delayed IL1b secretion. This was accompanied by higher levels of lL1Ra and IL-6 without any significant differences in IL-8. Interestingly, parents carrying the mutation also displayed higher levels of secreted IL-1b compared to HD control group. Conclusion The I313V mutation is associated with a mild CAPS phenotype and with an incr…
Experimental on-demand recovery of entanglement by local operations within non-Markovian dynamics
2015
In many applications entanglement must be distributed through noisy communication channels that unavoidably degrade it. Entanglement cannot be generated by local operations and classical communication (LOCC), implying that once it has been distributed it is not possible to recreate it by LOCC. Recovery of entanglement by purely local control is however not forbidden in the presence of non-Markovian dynamics, and here we demonstrate in two all-optical experiments that such entanglement restoration can even be achieved on-demand. First, we implement an open-loop control scheme based on a purely local operation, without acquiring any information on the environment; then, we use a closed-loop s…