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showing 10 items of 3963 documents
Taloustieteellisen tutkimustiedon löydettävyys ja avoimuus Suomessa
2019
Digitalisaatio on alentanut tutkimustiedon etsimiskustannuksia merkittävästi ja mahdollistanut tutkimustiedon tehokkaamman leviämisen. Tästä huolimatta tutkijoiden omat julkaisukäytäntöihin liittyvät valinnat vaikuttavat edelleen tutkimusjulkaisujen löydettävyyteen Internetissä. Tämä katsaus valottaa Suomen yliopistojen taloustieteen professorien tutkimusten julkaisukäytäntöjä ja avoimuutta verkossa. Katsauksen kolme keskeistä havaintoa ovat: 1) Suurin osa professoreista on rekisteröitynyt usealle eri tutkimusjulkaisuja yhteen kokoavalle alustalle: 72 %:lla on ResearchGate-profiili, 67 %:lla IDEAS-profiili ja 58 %:lla Google Scholar Citationsprofiili, 2) professoreiden eniten viitatuista ar…
A case report of double etiology of ecthyma gangrenosum
2019
Abstract Rationale: Ecthyma gangrenosum is a cutaneous infection, most commonly occurring during sepsis evolution with Pseudomonas aeruginosa on an immunocompromised background. There have been rare case reports in previously healthy children and rarer are the cases with double etiology. Patient concerns: We present the case of a female Caucasian patient, aged 1 year and 8 months, who developed severe sepsis during flu evolution with predominant respiratory and cerebral manifestations. On admission, at skin level, there was noticed a necrotic coccygeal ulceration (with rapid increasing dimensions 0.5/0.5 cm in 24 hours), and with the transformation from a dry necrosis in a sphacelus at the …
The role of the European Society of Human Genetics in delivering genomic education
2021
The European Society of Human Genetics (ESHG) was founded in 1967 as a professional organisation for members working in genetics in clinical practice, research and education. The Society seeks the integration of scientific research and its implementation into clinical practice and the education of specialists and the public in all areas of medical and human genetics. The Society works to do this through many approaches, including educational sessions at the annual conference; training courses in general and specialist areas of genetics; an online resource of educational materials (EuroGEMS); and a mentorship scheme. The ESHG Education Committee is implementing new approaches to expand the r…
Mexican journals of educational research towards mainstream dissemination of science
2014
The purpose of this study is to analyze the Electronic Journal of Educational Research (REDIE) on its path towards the common manner of scientific dissemination. This research presents the evolution of Mexican policy with regards to the journals, the situation of the Educational Research Mexican journals, and its profundity relating to REDIE. In its evolution, there were three moments that stood out the most: the standardization of quality criteria, the digitalization and open access of the scientific journals, those that came together with REDIE like REDALYC and LATINDEX , and the individual initiatives of those journals that motivated the development of the scientific dissemination in Mex…
Elemental contamination of an open-pit mining area in the Peruvian Andes
2014
New technologies and higher prices of raw materials have promoted the expansion of mining activity throughout the world; if not properly regulated, this activity can lead to contamination of the local and regional environ- ment. The city of Cerro de Pasco is located close to a large open-pit mine and in recent years, several reports have pro- vided evidence of environmental contamination and related health problems. The aim of this paper is to evaluate the contamination in fluvial water, sediments and biological fluids from this area. The collective results show elevated metal and metalloid concentrations in rivers and sediments, especially in the areas downstream of the mine. For instance,…
90Yttrium-Ibritumomab Tiuxetan as First Line Treatment for Follicular Non-Hodgkin Lymphoma. 5 Year Results from an International Multicenter Phase II…
2016
Abstract Purpose Updated 5 year results are presented from the multicenter phase II trial of 90Yttrium-Ibritumomab-Tiuxetan (90YIT) as first line stand-alone therapy for patients with follicular lymphoma (FL). Patients and Methods 59 patients with CD20-positive FL grade 1 to 3a in stages II with bulky disease (n=12), III (n= 26), or IV (n=21), and in need for therapy, were enrolled between 05/2007 and 06/2010. They received 90YIT according to standard procedure (rituximab 250 mg/m2 days -7 and 0, then 90YIT 15 MBq/kg (0.4mCi/kg) day 0; patients with platelet counts below 150.000/ul but above 100.000/ul received only 11 MBq/kg). Primary end point was the clinical and molecular remission rate…
Comparison of non-Markovianity criteria in a qubit system under random external fields
2013
We give the map representing the evolution of a qubit under the action of non-dissipative random external fields. From this map we construct the corresponding master equation that in turn allows us to phenomenologically introduce population damping of the qubit system. We then compare, in this system, the time-regions when non-Markovianity is present on the basis of different criteria both for the non-dissipative and dissipative case. We show that the adopted criteria agree both in the non-dissipative case and in the presence of population damping.
High-level secretion of tumor necrosis factor-alpha contributes to hematopoietic failure in hairy cell leukemia [see comments]
1989
Hairy cell leukemia (HCL) is frequently associated with severe pancytopenia. The authors detected high levels of tumor necrosis factor (TNF)-alpha in the bone marrow serum of patients with HCL and found anti-TNF-alpha neutralizing monoclonal antibodies (MoAbs) to be able to enhance hematopoiesis of HCL patients in in vitro colony assays. As potent producers of TNF-alpha, hairy cells could be identified, thus implicating the malignant population in the pathogenesis of hematopoietic failure due to inappropriate secretion of this cytokine.
High-level secretion of tumor necrosis factor-alpha contributes to hematopoietic failure in hairy cell leukemia [see comments]
1989
Abstract Hairy cell leukemia (HCL) is frequently associated with severe pancytopenia. The authors detected high levels of tumor necrosis factor (TNF)-alpha in the bone marrow serum of patients with HCL and found anti-TNF-alpha neutralizing monoclonal antibodies (MoAbs) to be able to enhance hematopoiesis of HCL patients in in vitro colony assays. As potent producers of TNF-alpha, hairy cells could be identified, thus implicating the malignant population in the pathogenesis of hematopoietic failure due to inappropriate secretion of this cytokine.
CT and MR Imaging of Brain Tumors
1989
Our clinical population numbered 8516 patients with primary and metastatic brain tumors who underwent evaluation by computed tomography at the neurosurgical and neuroradiologic departments of the Berlin, Mainz, and Munich centers from 1975 to 1986 and at the Neurosurgical Department of Augsburg Central Hospital from 1983 to 1986. Table 5 lists all the tumors having an incidence greater than 1% in the total population; 98% of the lesions were confirmed histologically (open surgery, stereotactic biopsy, autopsy). “Rare” intracranial tumors having an incidence no greater than 1% are listed in Table 6. The frequencies of the individual tumor types correlate well with the statistical data report…