Search results for "Open"

showing 10 items of 3963 documents

Effect of EDTA root conditioning on the healing of intrabony defects treated with an enamel matrix protein derivative.

2006

Contains fulltext : 49580.pdf (Publisher’s version ) (Open Access) BACKGROUND: Regenerative periodontal therapy with an enamel matrix protein derivative (EMD) has been shown to promote regeneration in intrabony periodontal defects. However, in most clinical studies, root surface conditioning with EDTA was performed in conjunction with the application of EMD, and, therefore, it cannot be excluded that the results may also be attributable to the effect of the root conditioning procedure. The purpose of this study was to determine the effect of root conditioning on the healing of intrabony defects treated with EMD. METHODS: Twenty-four patients, each of whom exhibited one deep intrabony defect…

AdultMaleTissue engineering and reconstructive surgery [UMCN 4.3]Bone RegenerationRoot surfaceOral Surgical ProceduresBleeding on probingAlveolar Bone LossDentistryDerivativeDental Enamel ProteinsDouble-Blind MethodmedicineHumansProspective StudiesTooth RootEdetic AcidChelating AgentsEnamel paintbusiness.industryChemistryOpen flap debridementAttachment levelGingival indexvisual_artvisual_art.visual_art_mediumPeriodonticsConditioningFemalePeriodontal Indexmedicine.symptombusiness
researchProduct

Influence of Thymopentin on Antibody Response, and Monocyte and T Cell Function in Hemodialysis Patients Who Fail to Respond to Hepatitis B Vaccinati…

1990

We investigated the influence of thymopentin as an adjuvant for hepatitis B vaccination on in vitro monocyte and T cell function and in vivo antibody response in a prospective, placebo-controlled double-blind trial in 20 low- and nonresponders to hepatitis B vaccination on chronic hemodialysis. 50 mg thymopentin was given subcutaneously twice per week for 3 weeks, followed by 1 intramuscular injection of 40 micrograms HB-Vax and 3 subsequent injections of thymopentin. After 1 month, the patients were boostered with 40 micrograms HB-Vax. There was no significant difference in T cell and monocyte function after administration of thymopentin, as determined in vitro. After 3 months, 3 patients …

AdultMaleViral Hepatitis VaccinesT-Lymphocytesmedicine.medical_treatmentT cellThymopoietinsMonocytesAdjuvants ImmunologicRenal DialysismedicineHumansThymopentinProspective StudiesHepatitis B AntibodiesAgedRandomized Controlled Trials as TopicAged 80 and overbusiness.industryMonocyteAntibody titerMiddle AgedHepatitis BHepatitis Bmedicine.diseasePeptide FragmentsThymus HormonesVaccinationmedicine.anatomical_structureImmunologyFemaleThymopentinIntramuscular injectionbusinessAdjuvantmedicine.drugNephron
researchProduct

Outcome of enzyme replacement therapy in patients with Gaucher disease type I. The Romanian experience

2007

This study reports the first evaluation of therapeutic response in Romanian patients with Gaucher disease type I, after therapy with Cerezyme recently became available in our country.24 patients (11-50 years) received Cerezyme 20-60 U/kg every two weeks for at least 18 months. Haemoglobin, platelet count, volume of the liver and spleen, plasma chitotriosidase and the severity score were assessed every 6 months; skeletal radiography and osteodensitometry were also monitored.Eleven patients were splenectomized before start of therapy. Eight patients had anaemia (mean haemoglobin 9.4 g/dl) and 14 patients, of whom 13 were without splenectomy, had thrombocytopenia (mean 65,692/mm3). Haemoglobin…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyPediatricsTime FactorsAdolescentBone diseasemedicine.medical_treatmentDiseaseWeight GainSeverity of Illness IndexHemoglobinsGeneticsmedicineHumansIn patientChildGenetics (clinical)ChemotherapyGaucher DiseasePlatelet CountRomaniabusiness.industryLiver DiseasesRomaniannutritional and metabolic diseasesAnemiaEnzyme replacement therapyMiddle Agedmedicine.diseaseCombined Modality TherapyThrombocytopeniaRecombinant Proteinslanguage.human_languageSurgeryHexosaminidasesTreatment OutcomeSplenomegalyQuality of LifeSplenectomylanguageGlucosylceramidaseFemaleBone DiseasesbusinessFollow-Up StudiesJournal of Inherited Metabolic Disease
researchProduct

Infant crying: pattern of weeping, recognition of emotion and affective reactions in observers.

2012

This study has three objectives: a) to describe the main differences in the crying patterns produced by the three affective states most closely related to crying: fear, anger and pain; b) to study the adults' accuracy in the recognition of the affective states related to the infant's crying, and c) to analyze the emotional reaction that infant crying elicits in the observers. Results reveal that the main differences appear in the ocular activity and in the pattern of weeping. The infants maintain their eyes open during the crying produced by fear and anger, but in the case of crying provoked by painful stimuli, the eyes remain closed almost all the time. In regard to the pattern of weeping,…

AdultMaleendocrine systemLinguistics and Languagemedia_common.quotation_subjectEmotionsPainCryingAngerAngerLanguage and LinguisticsDevelopmental psychologyYoung AdultEmotional reactionmedicineHumansInfant cryingEyes openGeneral Psychologymedia_commonAgedMaximum intensityFacial expressionCryingSocial perceptionInfantRecognition PsychologyFearMiddle AgedFacial ExpressionSocial PerceptionInfant BehaviorFemalemedicine.symptomPsychologyThe Spanish journal of psychology
researchProduct

Personality as a mediating variable in condom use among Spanish youth.

2015

Several studies have shown the influence of personality in risky sexual behaviors. This work has sought to establish which personality variables favor or hinder condom use in Spanish youth. A total of 408 young heterosexuals were assessed, divided into risk group (60.8%) and no-risk group (39.2%), according to systematic condom use. The results show statistically significant differences in Openness to Experience (p = .039), Conscientiousness (p = .047), Actions (p = .001), Competence (p = .024), and Self-discipline (p = .046). The regression analysis revealed that Compliance explained about 14 percent of the variance in condom use. The tendency to behave in a cooperative, peace-making, and …

AdultMalemedia_common.quotation_subjectSexual BehaviorHIV preventionPopulationcondom use050109 social psychologylaw.inventionDevelopmental psychologyCondoms03 medical and health sciencesYoung Adult0302 clinical medicineRisk-TakingCondomlawRisk FactorsSurveys and QuestionnairesOpenness to experiencePersonalityHumans0501 psychology and cognitive sciences030212 general & internal medicineYoung adulteducationContraception BehaviorApplied Psychologymedia_commonyoutheducation.field_of_studyrisky sexual behavior05 social sciencesConscientiousnessRegression analysispersonalitySpainRegression AnalysisFemalePsychologyDeveloped countryClinical psychologyPersonalityJournal of health psychology
researchProduct

Is laparoscopic approach still a risk factor for postappendectomy intra-abdominal abscess?

2020

Background The impact of laparoscopic appendectomy (LA) on the incidence of intra-abdominal abscess (IAA) remains controversial. We aimed to identify risk factors for postappendectomy IAA and assess the impact of appendectomy approach in postoperative morbidity. Methods A retrospective single-center study including consecutive patients who underwent appendectomy for acute appendicitis between 2015 and 2018 was performed. Demographic, clinical, intraoperative, and perioperative variables were collected. Univariate and multivariate analyses was performed to detect independent risk factors for IAA. Comparison of LA and open appendectomy was conducted, and propensity score model (PSM) was used …

AdultMalemedicine.medical_specialtyAbdominal AbscessCritical Care and Intensive Care MedicineYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsAppendectomyHumansMedicineRisk factorAbscessRetrospective StudiesPostoperative Carebusiness.industryIncidence (epidemiology)030208 emergency & critical care medicineRetrospective cohort studyPerioperativeMiddle AgedAppendicitismedicine.diseaseAppendicitisSurgeryLogistic ModelsPropensity score matchingCohortFemaleLaparoscopySurgerybusinessJournal of Trauma and Acute Care Surgery
researchProduct

Long-term clinical outcomes after percutaneous coronary intervention versus coronary artery bypass grafting for acute coronary syndrome from the DELT…

2016

AIMS Our aim was to compare, in a large unprotected left main coronary artery (ULMCA) all-comer registry, the long-term clinical outcome after percutaneous coronary intervention (PCI) with first-generation drug-eluting stents (DES) versus coronary artery bypass grafting (CABG) in patients with acute coronary syndrome (ACS). METHODS AND RESULTS Of a total of 2,775 patients enrolled in the Drug Eluting Stents for Left Main Coronary Artery Disease (DELTA) multicentre registry, 379 (13.7%) patients with ACS treated with PCI (n=272) or CABG (n=107) were analysed. Baseline demographics were considerably different in the two groups before propensity matching. No significant differences emerged for…

AdultMalemedicine.medical_specialtyAcute coronary syndromemedicine.medical_treatmentMyocardial Infarction030204 cardiovascular system & hematology03 medical and health sciencesPercutaneous Coronary Intervention0302 clinical medicineInternal medicineHumansMedicineRegistriescardiovascular diseases030212 general & internal medicineMyocardial infarctionAcute Coronary SyndromeCoronary Artery BypassStrokeAgedAged 80 and overbusiness.industryIncidence (epidemiology)Coronary StenosisPercutaneous coronary interventionDrug-Eluting StentsMiddle Agedmedicine.diseaseSurgeryStrokeTreatment Outcomemedicine.anatomical_structurePropensity score matchingConventional PCICardiologyFemaleCardiology and Cardiovascular MedicinebusinessArteryEuroIntervention
researchProduct

Predictors of mortality in HIV-infected patients starting antiretroviral therapy in a rural hospital in Tanzania

2008

Background Studies of antiretroviral therapy (ART) programs in Africa have shown high initial mortality. Factors contributing to this high mortality are poorly described. The aim of the present study was to assess mortality and to identify predictors of mortality in HIV-infected patients starting ART in a rural hospital in Tanzania. Methods This was a cohort study of 320 treatment-naïve adults who started ART between October 2003 and November 2006. Reliable CD4 cell counts were not available, thus ART initiation was based on clinical criteria in accordance with WHO and Tanzanian guidelines. Kaplan-Meier models were used to estimate mortality and Cox proportional hazards models to identify p…

AdultMalemedicine.medical_specialtyAdolescentAnemiaHospitals RuralHIV InfectionsKaplan-Meier EstimateTanzanialcsh:Infectious and parasitic diseasesCohort StudiesRisk FactorsInternal medicinemedicineHumanslcsh:RC109-216Survival analysis:Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801 [VDP]SurveillanceProportional hazards modelbusiness.industryHazard ratioMalnutritionAnemiaMiddle Agedmedicine.diseasePrognosisSurvival AnalysisThrombocytopenia:Medisinske Fag: 700::Helsefag: 800::Forebyggende medisin: 804 [VDP]SurgeryMalnutritionInfectious DiseasesAnti-Retroviral AgentsFemalebusinessRisk assessmentBody mass indexCohort studyFollow-Up StudiesResearch ArticleBMC Infectious Diseases
researchProduct

Results of 200 intracranial stereotactic biopsies

1994

200 stereotactic biopsies were evaluated. The validity of the intraoperative histopathological results were compared with the final diagnosis using conventional embedding and staining techniques. Further comparison between the histology of the biopsy and the post mortem or open operative findings were possible in 41 cases. Discrepancy was found in one case regarding the tumor detection, and in three cases regarding the tumor grading. The mortality in our patients was 1% and the morbidity 3%. Stereotactical biopsy had a low risk even in deep brain regions such as basal ganglia, mesencephalon, and pons. At the same time the high histologic validity makes the CT-guided stereotactical biopsy re…

AdultMalemedicine.medical_specialtyAdolescentBiopsyStereotaxic TechniquesOpen ResectionBiopsymedicineTumor GradingHumansChildAgedmedicine.diagnostic_testBrain Neoplasmsbusiness.industryBrainReproducibility of ResultsHistologyGliomaGeneral MedicineMiddle AgedPalliative TherapyTumor detectionChild PreschoolFemaleSurgeryNeurology (clinical)RadiologyNeurosurgeryTomography X-Ray ComputedbusinessComplicationNeurosurgical Review
researchProduct

Elderly obese women display the greatest improvement in stair climbing performance after a 3-week body mass reduction program

2004

OBJECTIVE: To depict the general trends of muscle anaerobic performance in obese subjects within a wide range of age and body weight. DESIGN: Cross-sectional study for the measurement of lower limb maximal anaerobic power output with a modification of the Margaria stair climbing test in a large population of obese subjects of both genders within a wide span of age (18-80 y) and body mass index (BMI, 30-68 kg m(-2)). Furthermore, body composition was also determined by bioimpedance analysis in a representative subgroup, in order to evaluate the relationships between fat-free mass (FFM) and power output. SUBJECTS: A total of 1298 obese subjects (486 males, 812 females) from an Italian populat…

AdultMalemedicine.medical_specialtyAdolescentDiet ReducingEndocrinology Diabetes and MetabolismPhysical ExertionPopulationMedicine (miscellaneous)Physical exerciseBody Mass IndexSex FactorsWeight lossActivities of Daily LivingWeight LossmedicineHumansObesityMuscle SkeletaleducationExerciseAgedAged 80 and overeducation.field_of_studyNutrition and Dieteticsbusiness.industryStair climbingAge FactorsMiddle Agedmedicine.diseaseCombined Modality TherapyObesityTreatment OutcomeSarcopeniaBody CompositionExercise TestPhysical therapyFemalemedicine.symptombusinesshuman activitiesAnaerobic exerciseBody mass indexInternational Journal of Obesity
researchProduct