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showing 10 items of 3963 documents

Evaluation of the postural stability of elderly persons using time domain signal analysis

2012

A force platform is widely used in the evaluation of postural stability in man. Although an abundance of parameters are typically retrieved from force platform data, no uniform analysis of the data has been carried out. In general, the signal analysis does not analyze the underlying postural event, i.e., whether the signal consists of several small corrections or large excursions. In the present work, we studied the postural stability of 4589 elderly persons from Iceland on a force platform under visual and non-visual conditions during stance on a solid surface. We analyzed the internal relationship between frequently used time domain variables. In addition, we conducted a factor analysis u…

Aged 80 and overMaleSignal processingTime FactorsGeneral NeuroscienceWork (physics)PostureOpen-loop controllerStationary pointSignalSensory SystemsArticleOtorhinolaryngologyControl theoryPostural BalanceHumansForce platformFemaleNeurology (clinical)Time domainPsychologyFactor Analysis StatisticalPostural BalanceSimulationAged
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Slightly radiopaque uric acid calculi: impact upon therapeutic considerations?

1989

Ten patients with slightly radiopaque urinary calculi were treated by percutaneous litholapaxy or even open surgery. The stone analysis revealed uric acid as the main stone composite suggesting that these patients should have been treated by oral litholysis alone alkalinizing the urine and decreasing uric acid levels with allopurinol. CT density measurements proved that concrements with HE less than 600 can be successfully dissolved by oral medication alone. Twenty-four patients were subsequently treated by oral citrate alkalinizing the spontaneous urine to pH 6.8-7.2 dissolving even large staghorns within 6-8 weeks. CT density measurements have become a routine diagnostic procedure when po…

Aged 80 and overMalemedicine.medical_specialtyPercutaneousbusiness.industryUrologyUrinary systemOpen surgeryHydrogen-Ion ConcentrationMiddle Agedurologic and male genital diseasesStone analysisSurgeryUric Acidchemistry.chemical_compoundKidney CalculichemistryLitholapaxyMedicineUric acidHumansFemalebusinessTomography X-Ray ComputedAgedUrologia internationalis
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Surgical repair of popliteal artery aneurysms remains a safe treatment option in the endovascular era: a 10-year single-center study

2012

Introduction: Endovascular popliteal artery aneurysm repair has emerged recently as a feasible alternative to standard surgical repair. However the evidence from the literature is still limited, with only case reports, case series and one small randomized trial. Currently these data suggest the use of stent-grafts in patients at very high surgical risk. The purpose of this study is to present our surgical experience in popliteal artery aneurysm repair in an era of endovascular philosophy. Materials and Methods: Data from 36 consecutive patients who were admitted to our hospital from January 2000 to April 2010, were analyzed retrospectively. Twenty-six patients underwent surgical treatment t…

Aged 80 and overTime FactorsPopliteal arteryEndovascular ProceduresMiddle AgedAneurysmSettore MED/22 - Chirurgia VascolareAneurysm; Popliteal artery; Open Repair; OutcomeHumansOpen RepairAgedFollow-Up StudiesRetrospective StudiesOutcome
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Relaciones entre las actitudes sexistas, la comunicación familiar y la agresión hacia los iguales

2019

La violencia escolar entre iguales es una problemática con graves consecuencias psicosociales. Además, se produce en una etapa del ciclo vital en que la familia y las actitudes sexistas tienen cierta influencia en las conductas violentas de los adolescentes. Desde esta perspectiva, el objetivo del presente trabajo fue analizar posibles diferencias en el sexismo hostil, sexismo benevolente, comunicación con la madre y comunicación con el padre entre tres grupos de adolescentes establecidos según su diferente implicación en violencia hacia los iguales: “baja implicación”, “implicación ocasional” y “implicación frecuente”. La muestra estuvo compuesta por 1034 adolescentes de ambos sexos (50.6%…

Aggression05 social sciencesPerspective (graphical)medicine050109 social psychology0501 psychology and cognitive sciencesmedicine.symptomOpen communicationPsychologyPsychosocial050104 developmental & child psychologyDevelopmental psychologyInternational Journal of Developmental and Educational Psychology. Revista INFAD de Psicología.
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Mortality attributable to COVID-19 in nursing home residents: a retrospective study

2021

AbstractAimCoronavirus-19 disease (COVID-19) is a widespread condition in nursing home (NH). It is not known whether COVID-19 is associated with a higher risk of death than residents without COVID-19. Therefore, the aim of this study was to assess whether COVID-19 is associated with a higher mortality rate in NH residents, considering frailty status assessed with the Multidimensional Prognostic Index (MPI).MethodsIn this retrospective study, made in 31 NHs in Venice, Italy, the presence of COVID-19 was ascertained with a nasopharyngeal swab. Frailty was evaluated using the MPI, modified according to the tools commonly used in our NHs. A Cox’s regression analysis was used reporting the resul…

AgingDiseaseCOVID-19 · Nursing home · Prognosis · Multidimensional prognostic index · Frailty comprehensive geriatric assessmen03 medical and health sciences0302 clinical medicineMultidimensional prognostic indexHumansMedicineFrailty comprehensive geriatric assessment030212 general & internal medicineMortalityGeriatric AssessmentAgedRetrospective StudiesAged 80 and overNursing homeSARS-CoV-2business.industryIncidence (epidemiology)Mortality rateConfoundingHazard ratioCOVID-19Retrospective cohort studyPrognosisConfidence intervalNursing HomesItalyPropensity score matchingOriginal ArticleFemaleGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryDemography
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Pain Increases the Risk for Sarcopenia in Community-Dwelling Adults: Results From the English Longitudinal Study of Ageing

2023

AbstractBackgroundPain and sarcopenia are common in older people. Cross-sectional studies have reported a significant association between these two conditions, but cohort studies exploring pain as a potential risk factor for sarcopenia are scarce. Given this background, the aim of the present work was to investigate the association between pain (and its severity) at baseline, and the incidence of sarcopenia over 10 years of follow-up in a large representative sample of the English older adult population.MethodsPain was diagnosed using self-reported information and categorized as mild to severe pain at four sites (low back, hip, knee, and feet). Incident sarcopenia was defined as having low …

AgingELSA longitudinal older adults pain sarcopeniaGeriatrics and GerontologyThe Journals of Gerontology: Series A
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Physical Multimorbidity and Sarcopenia among Adults Aged ≥65 Years in Low- and Middle-Income Countries.

2022

<b><i>Introduction:</i></b> Physical multimorbidity is plausibly linked to sarcopenia. However, to date, only a few studies exist on this topic, and none have examined this association in low- and middle-income countries (LMICs). Thus, we aimed to investigate the association between multimorbidity and sarcopenia in a sample of older adults from six LMICs (China, Ghana, India, Mexico, Russia, South Africa). <b><i>Methods:</i></b> Cross-sectional, community-based data from the WHO Study on Global Ageing and Adult Health (SAGE) were analysed. Sarcopenia was defined as having low skeletal muscle mass (SMM) and weak handgrip strength, while severe …

AgingEpidemiology Low- and middle-income countries Multi-country Multimorbidity Older adults SarcopeniaGeriatrics and GerontologyGerontology
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Role of Cachexia and Fragility in the Patient Candidate for Cardiac Surgery

2021

Frailty is the major expression of accelerated aging and describes a decreased resistance to stressors, and consequently an increased vulnerability to additional diseases in elderly people. The vascular aging related to frail phenotype reflects the high susceptibility for cardiovascular diseases and negative postoperative outcomes after cardiac surgery. Sarcopenia can be considered a biological substrate of physical frailty. Malnutrition and physical inactivity play a key role in the pathogenesis of sarcopenia. We searched on Medline (PubMed) and Scopus for relevant literature published over the last 10 years and analyzed the strong correlation between frailty, sarcopenia and cardiovascular…

AgingFood intakemedicine.medical_specialtyCachexiaMEDLINElcsh:TX341-641Reviewfrailtymalnutrition030204 cardiovascular system & hematologyage related syndromeCachexiasarcopeniaSettore MED/34Eating03 medical and health sciences0302 clinical medicinePreoperative CaremedicineHumansAge related syndrome Frailty Malnutrition SarcopeniaSettore MED/05 - Patologia Clinica030212 general & internal medicineCardiac Surgical ProceduresIntensive care medicineNutrition and Dieteticsbusiness.industryStressorPreoperative ExerciseResistance Trainingmedicine.diseaseCardiac surgeryMalnutritionPhenotypevascular agingCardiovascular DiseasesSarcopeniaBlood VesselsVascular agingSedentary Behaviorbusinesslcsh:Nutrition. Foods and food supplyBiomarkersFood ScienceNutrients
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Mitochondrial Markers in Aging and Primary Open-Angle Glaucoma

2020

This review focuses on recent progress in understanding the role of mitochondrial markers in the context of mitochondrial dysfunction in glaucoma and discussing new therapeutic approaches to modulate mitochondrial function and potentially lead to improved outcomes in glaucoma.

AgingMitochondrial Diseasesgenetic structuresOpen angle glaucomabusiness.industryGlaucomaContext (language use)medicine.diseaseBioinformaticseye diseasesOphthalmologyRetinal DiseasesmedicineHumanssense organsbusinessBiomarkersGlaucoma Open-AngleJournal of Glaucoma
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Update on the ESCEO recommendation for the conduct of clinical trials for drugs aiming at the treatment of sarcopenia in older adults

2020

Abstract Background In 2016, an expert working group was convened under the auspices of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and formulated consensus recommendations for the conduct of clinical trials for drugs to prevent or treat sarcopenia. Aims The objective of the current paper is to provide a 2020 update of the previous recommendations in accordance with the evidence that has become available since our original recommendations. Methods This paper is based on literature reviews performed by members of the ESCEO working group and followed up with face to face meetings organized for the whole group to make amendments and discuss…

AgingSarcopeniaGeriatrics & GerontologyStandardizationDiseaseReviewRecommendationsFace-to-face0302 clinical medicineQUALITY-OF-LIFEGAIT SPEEDClinical trial; Drug registration; Guidelines; Recommendations; Sarcopenia; Treatment; Aged; Humans; Muscle Strength; Osteoarthritis; Osteoporosis; Pharmaceutical Preparations; Sarcopenia030212 general & internal medicineMUSCLE MASSDIETARY-PROTEINClinical trialPhysical limitationsPharmaceutical Preparations/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingPatient-reported outcomeGRIP STRENGTHLife Sciences & Biomedicinemedicine.medical_specialtyNUTRITIONAL-STATUSBODY-COMPOSITION030209 endocrinology & metabolismGuidelines03 medical and health sciencesClinical trial · Sarcopenia · Guidelines · Recommendations · Drug registration · TreatmentSDG 3 - Good Health and Well-beingOsteoarthritismedicineHumansMuscle StrengthDrug registrationAgedScience & Technologybusiness.industryWORKING GROUPmedicine.diseaseComorbidityClinical trialTreatmentSarcopeniaPATIENT-REPORTED OUTCOMESPhysical therapyOsteoporosisGeriatrics and GerontologyPHYSICAL PERFORMANCEbusinessAging Clinical and Experimental Research
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