Search results for "Opera"

showing 10 items of 8665 documents

Does Preoperative Treatment with a Gonadotropin-Releasing Hormone Agonist Improve the Outcome of Endometrial Resection?

1998

Abstract Study Objective. To verify if more favorable long-term results of endometrial resection can be obtained with preoperative gonadotropin-releasing hormone (GnRH) agonist treatment. Design. Multicenter, randomized, controlled trial (Canadian Task Force classification I). Setting. Tertiary care academic department. Patients. Sixty-three premenopausal women with established menorrhagia. Intervention. Eight weeks of goserelin depot treatment before endometrial resection or immediate surgery in the early proliferative phase of the cycle. Measurements and Main Results. Variations in menstrual patterns and bleeding scores as well as overall degree of satisfaction with treatment were determi…

AdultAgonistmedicine.medical_specialtyAntineoplastic Agents Hormonalmedicine.drug_classlaw.inventionEndometriumRandomized controlled triallawGonadotropin-releasing hormone agonistPreoperative CareFollicular phaseElectrocoagulationmedicineHumansProspective StudiesMenorrhagiabusiness.industryGoserelinObstetrics and GynecologyEndoscopyMiddle AgedSurgeryExact testTreatment OutcomeDelayed-Action PreparationsUterine NeoplasmsGoserelinFemaleAmenorrheamedicine.symptombusinessAdenomyomamedicine.drugHormone
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Effect of epidural anesthesia on colorectal anastomosis: a tonometric assessment.

1997

PURPOSE: Epidural anesthesia is believed to benefit colorectal anastomotic blood flow because of the sympathetic blockade it produces. Our purpose is to measure with tonometry the effect of epidural anesthesia on colorectal anastomotic oxygenation. PATIENTS AND METHODS: Fifteen patients operated on for rectal cancer (radical anterior resection) were monitored postoperatively using tonometers placed in the stomach (celiac trunk), transverse colon (superior mesenteric artery), and the anastomotic area during the operation. An epidural catheter was placed at L1-2, and on the first postoperative day, 8 ml of bupivacaine (0.25 percent) was administered. The anesthetic effect extended up to T-4. …

AdultAnesthesia EpiduralMalemedicine.medical_specialtyColonRectumAnastomosisIntestinal mucosamedicine.arterymedicineHumansSuperior mesenteric arteryIntestinal MucosaAgedBupivacainePain Postoperativebusiness.industryStomachAnastomosis SurgicalGastroenterologyTransverse colonRectumGeneral MedicineHydrogen-Ion ConcentrationMiddle AgedBupivacaineColorectal surgerySurgeryOxygenmedicine.anatomical_structureGastric MucosaRegional Blood FlowAnesthesiaFemalebusinessColorectal Neoplasmsmedicine.drugDiseases of the colon and rectum
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AMH MEASUREMENT VERSUS OVARIAN ULTRASOUND IN THE DIAGNOSIS OF POLYCYSTIC OVARY SYNDROME IN DIFFERENT PHENOTYPES.

2015

This study was designed to assess the value of serum anti-Müllerian hormone (AMH) in the diagnosis of polycystic ovary syndrome (PCOS) in various phenotypes and to assess ovarian ultrasound parameters.We performed a retrospective matched controlled study of 113 females with various PCOS phenotypes and 47 matched controls. The diagnostic utility of AMH measurement and ovarian ultrasound were compared. Using receiver operating characteristic (ROC) curve analyses, the threshold for AMH (4.7 ng/mL) and ultrasound parameters (follicle number per ovary [FNPO]22 and ovarian volume [OV]8 cc) were established.In the entire cohort, AMH had a low sensitivity of 79%; while FNPO and OV were 93% and 68%,…

AdultAnti-Mullerian Hormoneendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and Metabolism030209 endocrinology & metabolismOvaryDiagnostic Techniques Endocrine03 medical and health sciencesFollicleYoung Adult0302 clinical medicineEndocrinologymedicineHumansRetrospective StudiesUltrasonographyGynecology030219 obstetrics & reproductive medicineReceiver operating characteristicbiologybusiness.industryUltrasoundOvaryCase-control studyAnti-Müllerian hormoneRetrospective cohort studyGeneral MedicinePolycystic ovaryfemale genital diseases and pregnancy complicationsmedicine.anatomical_structurePhenotypeROC CurveCase-Control Studiesbiology.proteinFemalebusinessPolycystic Ovary SyndromeEndocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
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Goldmann Tonometry After Hyperopic Laser In Situ Keratomileusis

2004

PURPOSE To identify differences in applanation tonometry between retreated and nonretreated eyes (primary LASIK eyes) 6 months after hyperopic laser in situ keratomileusis. METHODS In a prospective study 100 eyes (100 patients) underwent conventional hyperopic laser in situ keratomileusis under a 160-microm flap. Central Goldmann applanation tonometry was determined before and 6 months after surgery in 78 (78%) primary LASIK eyes and before surgery and 6 months after the retreatment date in 22 (22%) retreated eyes. RESULTS Preoperative mean tonometry was 14.96 +/- 1.96 mm Hg and 15.30 +/- 1.95 mm Hg in primary LASIK and retreated eyes, respectively. Six months after surgery it was 12.99 +/-…

AdultApplanation tonometrymedicine.medical_specialtyIntraocular pressureTime Factorsgenetic structuresmedicine.medical_treatmentKeratomileusis Laser In SitueducationKeratomileusisGoldmann applanation tonometryTonometry OcularmedicineHumansPostoperative PeriodProspective StudiesIntraocular Pressurebusiness.industrySignificant differenceLASIKhumanitieseye diseasesSurgeryGoldmann tonometryOphthalmologyHyperopiaTreatment OutcomeRetreatmentsense organsbusinessCornea
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Effect of lactose, lactulose and bisacodyl on gastrointestinal transit studied by metal detector.

2007

SUMMARY Aim and methods: To study the effect of 45 g lactose, 30 g lactulose and 10 mg bisacodyl on gastrointestinal transit in 30 healthy volunteers by metal detector and Hinton marker method. The first set of measurements were performed under standard conditions. In a second stage, transit was slowed to twice the original value by loperamide to simulate constipation conditions. Results: Bisacodyl drastically accelerated small and large intestinal transit. Colonic transit was shortened to 23 % and to 31% of control values, without and with loperamide. Bisacodyl increased stool weight and decreased stool consistency in all persons. Lactulose marginally shortened small intestinal transit (P=…

AdultBisacodylMalemedicine.medical_specialtyLoperamideConstipationColonmedicine.medical_treatmentLaxativeLactoseGastroenterologyLoperamideLactulosechemistry.chemical_compoundInternal medicineIntestine SmallmedicineHumansPharmacology (medical)Intestine LargeBisacodylLactoseDefecationGastrointestinal TransitHepatologyGastrointestinal transitdigestive oral and skin physiologyGastroenterologyLarge intestinalLactuloseMicrosphereschemistryGastric EmptyingFemalemedicine.symptommedicine.drugAlimentary pharmacologytherapeutics
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Factors associated with epiphora following orbital‐sparing maxillectomy via modified Weber–Ferguson incision with lower blepharoplasty

2021

Purpose The aims of the study were to estimate the frequency of epiphora and to identify factors associated with epiphora after orbital-sparing maxillectomy via modified Weber-Ferguson incision with lower blepharoplasty (OSOSM-MWFILB). Methods We performed a retrospective cohort study enrolling a sample derived from the patient population undergoing OSM-MWFILB over a 7-year period. The predictor variables were grouped into demographic, related health status, anatomic, tumor-specific, and therapeutic categories. The primary outcome variable was the presence of postmaxillectomy epiphora (PME). Descriptive, univariate, and multivariate regression mixed-effect models were computed. Results The …

AdultBlepharoplastyMaleBlepharoplastymedicine.medical_specialtyMultivariate statisticsmedicine.medical_treatment03 medical and health sciences0302 clinical medicineNeoplasmsMaxillamedicineOperating timeHumansIn patientAgedRetrospective StudiesAged 80 and overLacrimal Apparatus DiseasesTumor sizebusiness.industryUnivariateRetrospective cohort studyGeneral MedicineMiddle AgedPrognosisSurgeryOncology030220 oncology & carcinogenesisCarcinoma Squamous CellFemale030211 gastroenterology & hepatologySurgerybusinessComplicationOrbitOrgan Sparing TreatmentsFollow-Up StudiesJournal of Surgical Oncology
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The Association between Peripheral Blood Cells and the Frailty Syndrome in Patients with Cardiovascular Diseases

2020

Background: Frailty syndrome is characterized by multisystem dysregulation frequently found in older individuals or even in younger patients with chronic disabling diseases such as cardiovascular diseases. Objective: To determine whether peripheral blood cell count, and its subpopulations, red blood cell and platelets, morphology and different ratios (neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio and red blood distribution width-to-platelet ratio) are associated with cardiac frail patients, and through this to improve the prediction of frailty status in patients with cardiovascular diseases. Methods: An observational, retrospective, cohort study enrolling 179 patients with c…

AdultBlood PlateletsMalemedicine.medical_specialtyErythrocytesEndocrinology Diabetes and MetabolismFrailty syndromeperipheral blood countmalnutritionDiseaseArticleCohort StudiesYoung Adultneutrophil-to-lymphocyte ratioInternal medicinemedicineHumansImmunology and AllergyPeripheral blood cellNeutrophil to lymphocyte ratiowhite blood countAgedRetrospective StudiesAged 80 and overFrailtyReceiver operating characteristicred cell distribution width-to-platelet ratiobusiness.industryRed blood cell distribution widthMiddle Agedmedicine.diseaseplatelet-to-lymphocyte ratioCardiovascular diseasesCohortLeukocytes MononuclearFemalered blood cell distribution widthbusinessCohort studyEndocrine, Metabolic & Immune Disorders - Drug Targets
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Lack of prompt expansion of cytomegalovirus pp65 and IE-1-specific IFNγ CD8+ and CD4+ T cells is associated with rising levels of pp65 antigenemia an…

2009

Rising levels of cytomegalovirus (CMV) DNAemia and/or pp65 antigenemia have been observed during pre-emptive ganciclovir therapy in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-SCT). We assessed the incidence of this event in our series, and investigated whether its occurrence was associated with an impairment in the CMV-specific T-cell response. A total of 36 allo-SCT recipients experienced one or more episodes of active CMV infection (n=68) that were pre-emptively treated with val(ganciclovir). Rising levels of antigenemia and DNAemia, and an isolated increase in antigenemia, were observed in 39.7 and 2.9% of all episodes, respectively. Receipt of corticost…

AdultCD4-Positive T-LymphocytesMaleGanciclovirAdolescentvirusesCongenital cytomegalovirus infectionCytomegalovirusCD8-Positive T-LymphocytesOpportunistic Infectionsmedicine.disease_causeHerpesviridaeImmediate-Early ProteinsViral Matrix ProteinsInterferon-gammaYoung AdultAntigenBetaherpesvirinaeDrug Resistance ViralmedicineHumansTransplantation HomologousAntigens ViralGanciclovirAgedTransplantationbiologybusiness.industryHematopoietic Stem Cell Transplantationvirus diseasesHematologyMiddle AgedPhosphoproteinsbiology.organism_classificationmedicine.diseaseTransplantationsurgical procedures operativeCytomegalovirus InfectionsDNA ViralMutationImmunologyFemaleStem cellbusinessCD8medicine.drugBone Marrow Transplantation
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Relapse Analysis of Irradiated Patients Within the HD15 Trial of the German Hodgkin Study Group

2015

Purpose To determine, in the setting of advanced-stage of Hodgkin lymphoma (HL), whether relapses occur in the irradiated planning target volume and whether the definition of local radiation therapy (RT) used by the German Hodgkin Study Group (GHSG) is adequate, because there is no harmonization of field and volume definitions among the large cooperative groups in the treatment of advanced-stage HL. Methods and Materials All patients with residual disease of ≥2.5 cm after multiagent chemotherapy (CTX) were evaluated using additional positron emission tomography (PET), and those with a PET-positive result were irradiated with 30 Gy to the site of residual disease. We re-evaluated all sites o…

AdultCancer ResearchNeoplasm Residualmedicine.medical_treatmentPlanning target volumeIrradiated VolumeBleomycinFluorodeoxyglucose F18RecurrenceGermanyAntineoplastic Combined Chemotherapy ProtocolsHumansMedicineCooperative groupRadiology Nuclear Medicine and imagingRadiation treatment planningCyclophosphamideEtoposideChemotherapyRadiationmedicine.diagnostic_testbusiness.industryRadiotherapy Planning Computer-AssistedRadiotherapy DosageMiddle AgedCombined Modality TherapyHodgkin DiseaseRadiation therapyOncologyDoxorubicinVincristinePositron emission tomographyPositron-Emission TomographyProcarbazinePrednisoneHodgkin lymphomaRadiopharmaceuticalsbusinessNuclear medicineInternational Journal of Radiation Oncology*Biology*Physics
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Increase of CCR7- CD45RA+ CD8 T cells (TEMRA) in Chronic Graft-versus-host Disease

2006

Among the late effects of hematopoietic stem cell transplantation (HSCT), chronic graft-vs-host disease (cGVHD) still remains as the major determinant of long-term outcome and quality of life. The disease typically appears between 3 months to 1.5 years following an allogeneic transplantation and is characterized by symptoms similar to those of autoimmune disease.

AdultCancer ResearchReceptors CCR7Allogeneic transplantationmedicine.medical_treatmentGraft vs Host DiseaseC-C chemokine receptor type 7DiseaseHematopoietic stem cell transplantationCD8-Positive T-LymphocytesCCR7 CD45RA CD8Quality of lifemedicineCytotoxic T cellHumansLymphocyte CountAutoimmune diseasebusiness.industryHematologymedicine.diseasesurgical procedures operativeGraft-versus-host diseaseOncologyImmunologyChronic DiseaseLeukocyte Common AntigensReceptors ChemokinebusinessImmunologic Memory
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