Search results for "Operations"

showing 10 items of 1692 documents

Assessing statistical significance in multivariable genome wide association analysis

2016

Motivation: Although Genome Wide Association Studies (GWAS) genotype a very large number of single nucleotide polymorphisms (SNPs), the data are often analyzed one SNP at a time. The low predictive power of single SNPs, coupled with the high significance threshold needed to correct for multiple testing, greatly decreases the power of GWAS. Results: We propose a procedure in which all the SNPs are analyzed in a multiple generalized linear model, and we show its use for extremely high-dimensional datasets. Our method yields P-values for assessing significance of single SNPs or groups of SNPs while controlling for all other SNPs and the family wise error rate (FWER). Thus, our method tests whe…

0301 basic medicineStatistics and Probability1303 BiochemistryGenotypeOperations researchLibrary sciencePolymorphism Single NucleotideBiochemistryGerman03 medical and health sciences10007 Department of EconomicsPolitical scienceGenome-Wide Association Analysis1312 Molecular Biology1706 Computer Science ApplicationsCluster AnalysisHumansComputer Simulation2613 Statistics and ProbabilityMolecular BiologyEuropean researchGenetics and Population AnalysisComputational BiologyReproducibility of ResultsOriginal Paperslanguage.human_languageComputer Science Applications330 EconomicsComputational MathematicsPhenotype030104 developmental biologyComputational Theory and MathematicsLinear Modelslanguage2605 Computational MathematicsGenome-Wide Association Study1703 Computational Theory and Mathematics
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The adaptive value of tandem communication in ants:Insights from an agent-based model

2021

AbstractSocial animals often share information about the location of resources, such as a food source or a new nest-site. One well-studied communication strategy in ants is tandem running, whereby a leader guides a recruit to a resource. Tandem running is considered an example of animal teaching because a leader adjusts her behaviour and invests time to help another ant to learn the location of a resource more efficiently. Tandem running also has costs, such as waiting inside the nest for a leader and a reduced walking speed. Whether and when these costs outweigh the benefits of tandem running is not well understood. We developed an agent-based simulation model to investigate the conditions…

0301 basic medicineStatistics and ProbabilityForage (honey bee)Adaptive valueOperations researchComputer scienceForagingGeneral Biochemistry Genetics and Molecular BiologyRunning03 medical and health sciences0302 clinical medicineResource (project management)NestAnimalsLearningAgent-based modelGeneral Immunology and MicrobiologyTandemAntsCommunicationApplied MathematicsGeneral MedicineBeesVariable (computer science)030104 developmental biologyModeling and SimulationSocial animalFemaleGeneral Agricultural and Biological Sciences030217 neurology & neurosurgeryTandem running
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A webGIS-based system for real time shelf life prediction

2016

Technologies to acquire and monitor changes in the product shelf life were described.Four different SL predictive models were considered.A simulated transport using a prototype of Smart Logistic Unit was analysed.Real time shelf life prediction system was implemented in a webGIS platform. Shelf-life (SL) prediction and Least Shelf-life First Out (LSFO) stock strategy are important factors in perishable food supply chain in order to reduce quality and economic losses.In particular, distribution represents one of the main critical phases in logistic chain management and only the introduction of monitoring procedure can allow a reduction in food losses. Literature shows several mathematical mo…

0301 basic medicineTruckEngineeringWeb GISMathematical modelOperations researchbusiness.industrySupply chain030106 microbiologyReal-time computingForestry04 agricultural and veterinary sciencesHorticultureCommunications systemShelf life040401 food scienceAutomationComputer Science Applications03 medical and health sciences0404 agricultural biotechnologyAssisted GPSSettore ING-IND/17 - Impianti Industriali MeccaniciGlobal Positioning SystembusinessAgronomy and Crop Science
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Changes in the international wine market competitiveness

2017

This study offers a contribution to understanding the complexity of the international wine trade analysing the specialisation patterns of 14 among the most important wine world actors in the period 2007–2016, in order to verify if the patterns of comparative advantages for the trade of this countries have experienced significant changes. Using the Lafay index, as a comparative advantage measure, our results reveal deep changes in the global wine market exchange. Our result constitutes a base element for the future development of the competitive scenario and provides some both theoretical and practical implications. In the baseline projection, the maintenance of the competitive position is…

0301 basic medicineWineWine trade.030109 nutrition & dieteticsIndex (economics)Information Systems and ManagementComparative advantageTrade specialisationManagement Science and Operations Research03 medical and health sciencesOrder (exchange)Settore AGR/01 - Economia Ed Estimo RuralePosition (finance)BusinessElement (criminal law)Business and International ManagementBaseline (configuration management)Practical implicationsIndustrial organizationComparative advantageLafay indexInternational Journal of Globalisation and Small Business
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Curve Extraction by Geodesics Fusion: Application to Polymer Reptation Analysis

2016

© Springer International Publishing Switzerland 2016. In the molecular field, researchers analyze dynamics of polymers by microscopy: several measurements such as length and curvature are performed in their studies. To achieve correct analysis they need to extract the curve representing as good as possible the observed polymer shape which is a grayscale thick curve with noise and blur. We propose, in this paper, a method to extract such a curve. A polymer chain moves in a snake-like fashion (Reptation): it can self-intersect and form several complex geometries. To efficiently extract the different geometries, we generate the curve by computing a piecewise centerline browsing the shape by ge…

0301 basic medicine[ INFO ] Computer Science [cs]GeodesicGeometry02 engineering and technologyCurvature03 medical and health sciencesGraph traversalMolecular image analysis[INFO]Computer Science [cs]Grayscale curvesMorphological operationsdistanceMathematicsMicroscopyCurve orientationMathematical analysis021001 nanoscience & nanotechnologyReptation030104 developmental biologyGeodesics fusionPiecewiseShape extractionCurve sketching0210 nano-technologyShape analysis (digital geometry)
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Evaluating a hierarchical approach to landscape-level harvest scheduling

2018

Forest planning at the landscape level has the potential to become a large intractable problem. In Finland, Metsähallitus (the state enterprise that manages federally owned land) creates strategic plans to determine the appropriate harvest level. While these plans are feasible, they are not implementable in practice as the harvests are scattered temporally and spatially. Requiring that harvests be organized both temporally and spatially for practical implementation can result in an intractable problem. Through a hierarchical approach, the problem can be organized into steps in which the intractable problem is broken down into smaller easily solvable parts. As an approximation technique, th…

040101 forestryStrategic planningForest planningGlobal and Planetary ChangeIterative and incremental developmentOptimization problem010504 meteorology & atmospheric sciencesEcologyOperations researchComputer scienceForestry04 agricultural and veterinary sciences01 natural sciencesScheduling (computing)Landscape level0401 agriculture forestry and fisheriesState (computer science)Selection (genetic algorithm)0105 earth and related environmental sciencesCanadian Journal of Forest Research
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Groupthink and Project Performance: The Influence of Personal Traits and Interpersonal Ties

2015

Contains fulltext : 166103.pdf (Publisher’s version ) (Closed access) This study explores whether the negative impact of “groupthink concurrence-seeking behavior” (GTB) on business process reengineering (BPR) projects is affected by group members personal traits and interpersonal ties within the group. To this purpose we conduct and present the results of a longitudinal controlled field experiment over 18 BPR projects lasting 3 months and involving 18 teams comprising 71 first-year MBA students. The main contribution of this study is twofold. First, we explicitly consider and measure the core construct of groupthink phenomenon: that is, GTB. Existing organizational behavior literature has, …

05 social sciencesApplied psychologyConscientiousnessBehavioral operations managementInterpersonal communicationBusiness process reengineeringManagement Science and Operations ResearchSettore ING-IND/35 - Ingegneria Economico-GestionaleIndustrial and Manufacturing EngineeringBusiness process reengineeringInterpersonal tiesOrganizational behaviorPhenomenonConcurrence-seeking behaviorManagement of Technology and InnovationBehavioral operations management; Business process reengineering; Concurrence-seeking behavior; Groupthink; Industrial and Manufacturing Engineering; Management Science and Operations Research; Management of Technology and Innovation0502 economics and business050211 marketingPerceived controlMarketingPsychologyConstruct (philosophy)Institute for Management ResearchGroupthink050203 business & management
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Fuzzy Portfolio Selection Models for Dealing with Investor’s Preferences

2017

This chapter provides an overview of the authors’ previous work about dealing with investor’s preferences in the portfolio selection problem. We propose a fuzzy model for dealing with the vagueness of investor preferences on the expected return and the assumed risk, and then we consider several modifications to include additional constraints and goals.

050208 finance021103 operations researchActuarial scienceFinancial economicsComputer science05 social sciencesFuzzy model0211 other engineering and technologiesVagueness02 engineering and technologyFuzzy logicInvestor profile0502 economics and businessPortfolioExpected returnPortfolio optimizationSelection (genetic algorithm)
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The Impact of Lbos on Investment Policies and Operations of Acquired French Firms

2002

This paper evaluates the extent that French LBO targets’ investment policy and operations can account for their overperformance discrepancy. Our empirical study has been carried out on 132 French LBOs between 1989 and 1994. The results show that the abnormal plunge in economic return cannot be explained by overinvestments or by inefficient working capital management. Nevertheless, abnormal increases in wages, supplies and/or sales price reductions appear to be prominent.

050208 finance05 social sciencesWorking capitalEconomic returnjel:G31Monetary economicsInvestment policyInvestment (macroeconomics)General Business Management and AccountingEmpirical research0502 economics and business8. Economic growthBusinessLeveraged buy-out;performance;investment policy;operationsSale price050203 business & management
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Early warning of systemic risk in global banking: eigen-pair R number for financial contagion and market price-based methods

2021

AbstractWe analyse systemic risk in the core global banking system using a new network-based spectral eigen-pair method, which treats network failure as a dynamical system stability problem. This is compared with market price-based Systemic Risk Indexes (SRIs), viz. Marginal Expected Shortfall (MES), Delta Conditional Value-at-Risk (Delta-CoVaR), and Conditional Capital Shortfall Measure of Systemic Risk (SRISK) in a cross-border setting. Unlike paradoxical market price based risk measures, which underestimate risk during periods of asset price booms, the eigen-pair method based on bilateral balance sheet data gives early-warning of instability in terms of the tipping point that is analogou…

050208 financeFinancial contagionParadoxical risk measures05 social sciencesGlobal financial networksGeneral Decision SciencesManagement Science and Operations ResearchTipping point (climatology)Statistical market price-based risk measuresEigen-pair analysisCapital (economics)0502 economics and businessSystemic riskMarket priceCapital requirementSystemic riskEconomicsEconometricsBalance sheetEarly warning signalsAsset (economics)050207 economicsOR in bankingAnnals of Operations Research
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