Search results for "Operative"

showing 10 items of 2781 documents

Microcirculatory Assessment of Arterial Below-Knee Stumps: Near-Infrared Spectroscopy Versus Transcutaneous Oxygen Tension—A Preliminary Study in Pro…

2017

International audience; Objective: To examine metrologic properties of near-infrared spectroscopy (NIRS) versus transcutaneous oxygen tension (TcPO2) for micro-circulatory assessment of vascular transtibial stumps at the stabilized period of prosthesis fitting, as a preliminary step before exploring its ability to predict stump healing, considering the previously identified limits of TcPO2 (borderline area between 15 and 35mmHg).Design: Prospective single-center observational study.Setting: University-based rehabilitation center.Participants: Individuals with unilateral transtibial amputation for peripheral artery disease, at the definitive stage of prosthesis fitting, able to perform a 2-m…

Male030506 rehabilitationFuture studiesSupine positionArterial diseaseIntraclass correlationmedicine.medical_treatmentamputees030204 cardiovascular system & hematologynear-infraredProsthesischemistry.chemical_compound0302 clinical medicinenoninvasive methodsMedicineProspective StudiesSpectroscopyAged 80 and overSpectroscopy Near-InfraredAmputation stumpsexerciseRehabilitationMiddle Aged[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system3. Good healthsurgical procedures operativeAnesthesiaFemale0305 other medical scienceAdultcritical limb ischemiamedicine.medical_specialtyVisual analogue scaleArtificial LimbsPhysical Therapy Sports Therapy and RehabilitationAmputation SurgicalBlood gas monitoringPeripheral Arterial Disease03 medical and health sciences[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemlevelpressure measurements[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyHumansTCPOPhysical Therapy ModalitiesAgedbusiness.industryMicrocirculationtest-retest reliabilityReproducibility of ResultsbalancetranscutaneousSurgeryOxygenperipheral vascular-diseasechemistrylower-extremity amputationTranscutaneous oxygenbusiness[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyArchives of Physical Medicine and Rehabilitation
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Participation in collaborative projects as a precursor of trust in organizations for individuals with intellectual disability

2020

The present study focuses on organizations delivering services to individuals with intellectual disability, where trust relations between professionals and family members are required. More specifically, we examine the existence of significant differences in the degree to which family members and professionals trust each other. We also propose that their joint participation in collaborative teams (VI) will improve trust (VD). Specifically, our teams (experimental condition) designed and implemented collaborative projects with the participation of professionals and family members. Participants in the control condition did not participate in the collaborative projects. Our results confirmed t…

Male030506 rehabilitationSocial psychology (sociology)Applied psychologySocial SciencesTime MeasurementMedical ConditionsCognitionSociologySurveys and QuestionnairesIntellectual disabilityMedicine and Health SciencesPsychologyCooperative BehaviorIntersectoral CollaborationQualitative Researchhealth care economics and organizationsMeasurementMultidisciplinaryExperimental DesignQ05 social sciencesRMiddle AgedhumanitiesNeurologyResearch DesignEngineering and TechnologyMedicineFemale0305 other medical sciencePsychologyResearch ArticleSocial theoryAdultSocial PsychologyDisabilitiesScienceDecision MakingeducationControl (management)Social TheoryResearch and Analysis MethodsTrust03 medical and health sciencesQuality of life (healthcare)Intellectual Disability0502 economics and businessmedicineSpeechHumansFamilySocial BehaviorPatient Care TeamOrganizationsCognitive PsychologyBiology and Life SciencesLinguisticsmedicine.diseaseHealth CareQuality of LifeCognitive Science050203 business & managementNeurosciencePLOS ONE
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Effectiveness of postoperative home-exercise compared with usual care on kinesiophobia and physical activity in spondylolisthesis:A randomized contro…

2017

Objective: To study the effectiveness of a 12-month exercise therapy on kinesiophobia and physical activity in patients with spondylolisthesis after lumbar spine fusion. Design: Randomized controlled trial. Subjects: Patients (n = 98) with spondylolisthesis who had undergone lumbar spine fusion. Methods: All patients (mean age 59 years) had received lumbar spine fusion surgery and identical postoperative instructions. Three months postoperatively, they were randomized into an exercise group (n = 48) or usual care group (n = 50). The exercise group received 12-month progressive home-based training with regular booster sessions, and the usual care group a single session of physiotherapy instr…

Male030506 rehabilitationmedicine.medical_specialtymedicine.medical_treatmentspondylolisteesiPhysical activityPhysical Therapy Sports Therapy and RehabilitationMetabolic equivalentfysioterapialaw.inventionspondylolyysi03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationRandomized controlled triallawselkäsairaudetmedicineHumansPostoperative PeriodPhysical Therapy Modalitieslow back painphysical therapy modalitiesbusiness.industryRehabilitationGeneral MedicineMiddle Agedmedicine.diseaseLow back painSpondylolisthesis3. Good healthExercise TherapyQuartileSpinal fusionUsual carespinal fusionPhysical therapyFemalekuntoutusmedicine.symptomSpondylolisthesis0305 other medical sciencebusiness030217 neurology & neurosurgeryliikuntahoito
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Improve hip fracture outcome in the elderly patient (iHOPE) : A study protocol for a pragmatic, multicentre randomised controlled trial to test the e…

2018

IntroductionHip fracture surgery is associated with high in-hospital and 30-day mortality rates and serious adverse patient outcomes. Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia on patient-centred outcomes after hip fracture surgery is sparse.Methods and analysisThe iHOPE study is a pragmatic national, multicentre, randomised controlled, open-label clinical trial with a two-arm parallel group design. In total, 1032 patients with hip fracture (>65 years) will be randomised in an intended 1:1 allocation ratio to receive spinal anaesthesia (n=516) or general anaesthesia (n=516). Outcome assessment will occur in a blinded manner aft…

Male1682medicine.medical_specialtyArthroplasty Replacement HipMedizinAnesthesia GeneralAnesthesia Spinallaw.inventionAnaesthesia03 medical and health sciencesClinical Trial Protocols as TopicPostoperative Complications0302 clinical medicineRandomized controlled trial030202 anesthesiologylawPragmatic Clinical Trials as TopicProtocolClinical endpointHumansMulticenter Studies as TopicMedicineGeneral anaesthesia1506ddc:610030212 general & internal medicineAgedRandomized Controlled Trials as TopicPain PostoperativeHip fracturegeriatric medicineHip Fracturesbusiness.industryMedical recordanaesthesia in orthopaedicsGeneral MedicinePerioperativeMiddle Agedmedicine.diseaseanaestheticsClinical trialTelephone interviewResearch DesignPhysical therapyFemalebusiness
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Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease.

2016

Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; BACKGROUND Chronic graft-versus-host disease (GVHD) is the leading cause of later illness and death after allogeneic hematopoietic stem-cell transplantation. We hypothesized that the inclusion of antihuman T-lymphocyte immune globulin (ATG) in a myeloablative conditioning regimen for patients with acute leukemia would result in a significant reduction in chronic GVHD 2 years after allogeneic peripheral-blood stem-cell transplantation from an HLA-identical sibling. METHODS We conducted a prospective, multicenter, open-label, randomized phase 3 study of ATG as part of …

Male:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Proportional Hazards Models [Medical Subject Headings]T-LymphocytesPhases of clinical researchGraft vs Host Disease:Named Groups::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]Linfocitos t:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Immunosuppressive Agent0302 clinical medicineTrasplante homólogoEstudios prospectivosMedicineCumulative incidenceProspective StudiesProspective cohort studyChildTransplantation Homologou:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Immunoproteins::Immunoglobulins::Antibodies::Immune Sera::Antilymphocyte Serum [Medical Subject Headings]Acute leukemia:Anatomy::Cells::Blood Cells::Leukocytes::Leukocytes Mononuclear::Lymphocytes::T-Lymphocytes [Medical Subject Headings]:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]:Named Groups::Persons::Age Groups::Child::Child Preschool [Medical Subject Headings]Medicine (all)IncidenceSuero antilinfocíticoGeneral MedicineMiddle AgedModelos de riesgos proporcionales3. Good healthHumanosSurvival Rate030220 oncology & carcinogenesis:Named Groups::Persons::Age Groups::Adolescent [Medical Subject Headings]Child PreschoolFemale:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Immunologic Factors::Immunosuppressive Agents [Medical Subject Headings]Immunosuppressive AgentsHumanHomologousAdultmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Longitudinal Studies::Prospective Studies [Medical Subject Headings]:Named Groups::Persons::Age Groups::Adult::Young Adult [Medical Subject Headings]AdolescentEnfermedad injerto contra huéspedDisease-Free Survival03 medical and health sciencesYoung AdultInternal medicine:Named Groups::Persons::Age Groups::Adult [Medical Subject Headings]HumansTransplantation HomologousSupervivencia sin enfermedadPreschoolSurvival rate:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Disease-Free Survival [Medical Subject Headings]:Named Groups::Persons::Age Groups::Child [Medical Subject Headings]Antilymphocyte SerumProportional Hazards ModelsTransplantationbusiness.industryEnfermedad crónicamedicine.diseaseInmunosupresoresAnti-thymocyte globulinSurgeryTransplantation:Diseases::Immune System Diseases::Graft vs Host Disease [Medical Subject Headings]Prospective Studie:Analytical Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures Operative::Transplantation::Transplantation Homologous [Medical Subject Headings]Graft-versus-host diseaseT-Lymphocyte:Check Tags::Female [Medical Subject Headings]Chronic DiseaseProportional Hazards ModelAdolescent; Adult; Antilymphocyte Serum; Child; Child Preschool; Chronic Disease; Disease-Free Survival; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Survival Rate; T-Lymphocytes; Transplantation Homologous; Young Adult; Medicine (all)business030215 immunology
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Influence of PEEP on cerebral blood flow and cerebrovascular autoregulation in patients with acute respiratory distress syndrome.

2013

High levels of positive end-expiratory pressure (PEEP), as part of the treatment in patients with acute respiratory distress syndrome (ARDS), may prevent alveolar collapse and maintain oxygenation. PEEP potentially reduces cerebral venous return, increases intracranial blood volume, and may, therefore, affect cerebral blood flow (CBF) and cerebrovascular autoregulation (AR). This study investigates the effect of PEEP on CBF and AR in patients with respiratory failure.CBF velocity was measured using transcranial doppler and correlated with the invasive arterial blood pressure curve to calculate the index of AR Mx (Mx0.3 indicates impaired AR). Mx was measured at lower PEEP levels and after i…

MaleARDSmedicine.medical_specialtyCritical CareUltrasonography Doppler TranscranialBlood volumeBlood PressurePreoperative carePositive-Pressure RespirationOxygen ConsumptionInternal medicinePreoperative CaremedicineHomeostasisHumansHypnotics and SedativesIn patientCollapse (medical)AgedAged 80 and overRespiratory Distress SyndromeBlood Volumebusiness.industryOxygenationrespiratory systemMiddle Agedmedicine.diseaserespiratory tract diseasesOxygenAnesthesiology and Pain MedicineCerebral blood flowCerebrovascular CirculationCardiologySurgeryFemaleNeurology (clinical)medicine.symptombusinesstherapeuticsVenous return curvecirculatory and respiratory physiologyJournal of neurosurgical anesthesiology
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Fixation-free incisional hernia repair in the elderly: our experience with a tentacle-shaped implant.

2016

Background: Incisional hernia in aged patients represents a challenge even for experienced surgeons. Besides increased risk of complications due to comorbidities, mesh fixation and assuring a sufficient mesh overlap of the defect are the main issues in carrying out the repair. Aims: In order to assure broader coverage of the abdominal wall and a tension- and fixation-free repair, a specifically designed prosthesis was developed for the surgical treatment of incisional hernias. The results of a fixation-free incisional hernia repair carried out in elderly patients using a tentacle-shaped implant are reported herewith. Methods: A tentacle-shaped flat mesh with a large central body and integra…

MaleAgingmedicine.medical_specialtyAbdominal Wound Closure TechniquesFrictionIncisional herniamedicine.medical_treatment030230 surgeryProsthesisAbdominal wall03 medical and health sciences0302 clinical medicineHematomaPostoperative ComplicationsRecurrenceSublaymedicineHumansIncisional HerniaAgedAged 80 and overSurgical fixation deviceTentacle meshbusiness.industryAbdominal Wound Closure TechniquesProstheses and ImplantsSurgical Meshmedicine.diseaseHernia VentralSurgerysurgical procedures operativemedicine.anatomical_structureSurgical meshVentral herniaOutcome and Process Assessment Health Care030220 oncology & carcinogenesisTechniqueFemaleImplantGeriatrics and GerontologyFast trackbusinessAging clinical and experimental research
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The Size of Subconjunctival Preparation Does Not Influence the Outcome of Trabeculectomy With Mitomycin C

2014

PURPOSE To compare the outcome of fornix-based trabeculectomy with mitomycin C (MMC) using 2 different sizes of subconjunctival preparation (36 mm² compared with 72 mm²). METHODS Prospective, randomized interventional case series. STUDY POPULATION Patients 18 to 85 years of age with open-angle glaucoma and progressive visual field defects under maximum tolerated medical therapy were randomized to undergo initial fornix-based trabeculectomy with MMC (0.2 mg/mL for 5 min) with subconjunctival preparation of 6×6 mm (group A) or 8×9 mm (group B). Main outcome parameters were: intraocular pressure (IOP), best-corrected visual acuity (BCVA), number of 5-fluorouracil (5-FU) injections, and laser s…

MaleAlkylating Agentsmedicine.medical_specialtyIntraocular pressureVisual acuitygenetic structuresMitomycinmedicine.medical_treatmentVisual AcuityGlaucomaTrabeculectomyGroup BTonometry OcularPostoperative ComplicationsOphthalmologymedicineHumansTrabeculectomyProspective StudiesIntraocular PressureAgedAged 80 and overGlaucoma medicationbusiness.industryMitomycin CMiddle Agedmedicine.diseaseCombined Modality Therapyeye diseasesOphthalmologyTreatment OutcomePopulation studyFemaleFluorouracilsense organsmedicine.symptombusinessConjunctivaGlaucoma Open-AngleFollow-Up StudiesJournal of Glaucoma
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Models with clinically-relevant and life-threatening histamine-related cardiovascular disturbances: Evaluation of the clinical effectiveness of H1/H2…

1996

MaleAllergymedicine.medical_specialtyNeurologySwineClinical effectivenessImmunologyPharmacology toxicologyBlood PressureHistamine Receptor AntagonistsPharmacologyHistamine Releasechemistry.chemical_compoundDogsAnimalsp-Methoxy-N-methylphenethylamineMedicinePharmacologyChi-Square Distributionbusiness.industryPerioperativemedicine.diseaseDisease Models AnimalHistamine H2 AntagonistschemistryHistamine H1 AntagonistsSwine MiniatureFemaleHypotensionbusinessHistamineHistamineInflammation Research
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Efficacy of Periportal Infiltration and Intraperitoneal Instillation of Ropivacaine After Laparoscopic Surgery in Children

2009

Postoperative pain is less intense after laparoscopic than after open surgery. However, minimally invasive surgery is not a a pain-free procedure. Many trials have been done in adults using intraperitoneal and/or incisional local anesthetic, but similar studies have not yet been reported in the literature in children. Aim: The aim of this study was to evaluate the analgesic effect of periportal infiltration and intraperitoneal instillation of ropivacaine in children undergoing laparoscopic surgery. Materials and Methods: Thirty patients who underwent laparoscopic surgery were randomly allocated to one of three groups. Group A (n 10) received local infiltration of port sites with 10 mL of ro…

MaleAnalgesic effectLaparoscopic surgerymedicine.medical_specialtyAdolescentmedicine.drug_classmedicine.medical_treatmentAnalgesicBody Mass Indexlaw.inventionRandomized controlled triallawmedicineHumansInfusions ParenteralRopivacaineAnesthetics LocalChildPain MeasurementPain Postoperativebusiness.industryLocal anestheticRopivacaineOpen surgerySettore MED/20 - Chirurgia Pediatrica E Infantilelaparoscopic surgery periportal infiltrationmedicine.diseaseAmidesSurgeryInstillation DrugTreatment OutcomeAnesthesiaFemaleLaparoscopySurgerybusinessInfiltration (medical)medicine.drugJournal of Laparoendoscopic & Advanced Surgical Techniques
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