Search results for "Ophthalmology"
showing 10 items of 1738 documents
Orbitale Manifestation der IgG4-assoziierten Erkrankung: eine Fallserie
2019
ZusammenfassungDie IgG4-assoziierte Orbitopathie (IgG4-related orbital disease/IgG4 ROD) ist selten und gehört zu der erst in den letzten Jahren beschriebenen Multisystemerkrankung, der IgG4-assoziierten Erkrankung. Differenzialdiagnostisch ist sie von der idiopathischen orbitalen Entzündung, der endokrinen Orbitopathie und von einer orbitalen Neoplasie zu unterscheiden. Die Bildgebung mit MRT und eine Probenentnahme sind entscheidend für die Diagnose. Patienten mit dieser Erkrankung sprechen gut auf Steroide an. Im Folgenden werden 3 klinisch sehr unterschiedliche Manifestationen der orbitalen IgG4-assoziierten Erkrankung vorgestellt.
Preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% in patients with open-angle glaucoma and ocular hypertension: results of a…
2017
Lutz E Pillunat,1 Carl Erb,2 Auli Ropo,3 Friedemann Kimmich,4 Norbert Pfeiffer5 1Department of Ophthalmology, University Hospital Carl Gustav Carus, Dresden, 2Augenklinik am Wittenbergplatz, Berlin, Germany; 3Santen Europe, Helsinki, Finland; 4eyecons, Pfinztal, 5Department of Ophthalmology, Mainz University Medical Center, Mainz, Germany Background: Efficacy, tolerability and safety of the novel preservative-free fixed combination of tafluprost 0.0015%/timolol 0.5% (Taptiqom®) were investigated in an observational study in Germany.Objective: To assess efficacy, tolerability and safety of the preservative-free fixed combination of tafluprost 0.0015%/timolol 0.5% in a real-life setti…
Normal values for fundus perimetry with the MAIA microperimeter and short-term repeatability evaluation
2016
National audience; Purpose To assess retinal sensitivity by means of microperimetry and to evaluate the intersession fluctuation using the MAIA microperimeter in healthy volunteers. Methods Prospective, monocentre study. Fifty‐six healthy volunteers (age range, 20–80 years), underwent an automatic, full‐threshold microperimetry of the central field (custom grid, area of 10° in diameter, 37 stimulated points), with the MAIA microperimeter (CenterVue, Padova, Italy). A subgroup of 24 subjects was retested after 1 h (test 2) and 1 week (test 3) to determine the repeatability of the technique. A subgroup of 22 subjects was also tested on the OPKO microperimeter (Optos, Dunfermline, Scotland) (a…
In the shadow of threatening norms: How students with visual impairment contest and reproduce institutional positions
2020
This article focuses on semi-narrative guided interviews with students with visual impairment (VI) who attend a state-approved special school for students with VI at the time of the interview, although they had different previous experiences in both segregated and inclusive schools. We are conducting a qualitative analysis from the perspective of teenagers concerning how they negotiate institutional ascriptions of (dis)abilities. We have selected interview sequences of two young people: (a) Kai: self-confidence and internalized self-doubt and (b) Felix: between fighting and claiming ableist divides. Our analyses reveal the different ways of how Kai and Felix each contest the ableist divide…
How Long Did You Look At Me? The Influence of Gaze Direction on Perceived Duration and Temporal Sensitivity.
2016
Faces that exhibit emotionally negative expressions in mutual gaze have been shown to induce a dilation of perceived duration. The influence of gaze by itself on duration judgments, however, has rarely been investigated. We argue for a social interaction hypothesis, according to which humans should be highly accurate and precise (sensitive) when processing the temporal dynamics of mutual gaze. In three experiments, we investigated whether the direction of observed gaze affects perceived duration and temporal sensitivity. In Experiment 1, subjects did indeed estimate the duration of direct gaze more accurately as compared to the duration of averted gaze. In Experiments 2 and 3, subjects had…
What represents a face? A computational approach for the integration of physiological and psychological data.
1997
Empirical studies of face recognition suggest that faces might be stored in memory by means of a few canonical representations. The nature of these canonical representations is, however, unclear. Although psychological data show a three-quarter-view advantage, physiological studies suggest profile and frontal views are stored in memory. A computational approach to reconcile these findings is proposed. The pattern of results obtained when different views, or combinations of views, are used as the internal representation of a two-stage identification network consisting of an autoassociative memory followed by a radial-basis-function network are compared. Results show that (i) a frontal and a…
Changes of coagulation parameters during high altitude expedition
2010
Data on changes of haemostatic parameters at altitudes above 5000 m are very limited. So far it is unknown, whether altered coagulation could contribute to the development of acute mountain sickness.Thirty four healthy mountaineers were randomised to two acclimatisation protocols and undertook an expedition on Muztagh Ata (7549 m) in China. Tests were performed at five altitudes up to 6865 m. Haemostatic parameters, such as PT, aPTT, D-Dimer, APC-Resistance (APCR), von Willebrand Factor activity (RCo), ADAMTS-13C-Natriuretic Peptide (CNP) were assessed together with Lake Louise AMS score.D-Dimer significantly increased with increasing altitude (median 0.62 to 0.81 mcg/L, p0.0001). During as…
Repeatability of in-vitro optical quality measurements of intraocular lenses with a deflectometry technique effect of the toricity
2018
Aim To evaluate the repeatability of an optical device for measuring the Zernike coefficients of toric intraocular lenses (IOLs) and assess whether its toricity has any impact in its repeatability. Methods An experienced technician used the NIMO TR1504 to measure the Zernike coefficients 30 times for an aperture of 4.50 mm for all lenses included. The IOLs included were divided into two group: toric and non-toric ones. The cylindrical powers of the toric lenses included in the present study were 1.00, 1.50, 2.25, 3.00 and 3.75 D. Finally, the repeatability of the NIMO TR1504 was described in terms of within subject standard deviation (Sw) and repeatability limit. Results The Sw was smaller …
Cholestérol et pathologies oculaires : focus sur le rôle de la cholestérol 24S-hydroxylase (CYP46A1) dans l’homéostasie du cholestérol
2015
Resume La retine est le tissu neurosensoriel de l’œil qui assure la transduction visuelle, c’est-a-dire le codage de l’information lumineuse en influx nerveux. Le terme « retine » regroupe l’association de la retine neurale et de l’epithelium pigmentaire retinien qui repose sur la membrane de Bruch. L’association physique de ces deux partenaires et leurs interactions metaboliques sont des elements indispensables au bon fonctionnement de la retine, a la fois en termes d’apport en nutriments et de maintien de l’homeostasie. Des dereglements de ces equilibres sont associes au vieillissement et a des pathologies comme la degenerescence maculaire liee a l’âge, premiere cause de malvoyance apres …
Widening use of dexamethasone implant for the treatment of macular edema
2017
Vincenza Bonfiglio, Michele Reibaldi, Matteo Fallico, Andrea Russo, Alessandra Pizzo, Stefano Fichera, Carlo Rapisarda, Iacopo Macchi, Teresio Avitabile, Antonio Longo Department of Ophthalmology, University of Catania, Catania, Italy Abstract: Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis. The implant is formulated in a biodegradable copolymer to release the active ingredient within the vitreous chamber for up to 6 months after an intravitreal injection, allowing a prolonged interval of effica…