Search results for "Optics"
showing 10 items of 10033 documents
Remarks on GRN-type systems
2020
Systems of ordinary differential equations that appear in gene regulatory networks theory are considered. We are focused on asymptotical behavior of solutions. There are stable critical points as well as attractive periodic solutions in two-dimensional and three-dimensional systems. Instead of considering multiple parameters (10 in a two-dimensional system) we focus on typical behaviors of nullclines. Conclusions about possible attractors are made.
Generation and Coherent Control of Pulsed Quantum Frequency Combs
2018
We present a method for the generation and coherent manipulation of pulsed quantum frequency combs. Until now, methods of preparing high-dimensional states on-chip in a practical way have remained elusive due to the increasing complexity of the quantum circuitry needed to prepare and process such states. Here, we outline how high-dimensional, frequency-bin entangled, two-photon states can be generated at a stable, high generation rate by using a nested-cavity, actively mode-locked excitation of a nonlinear micro-cavity. This technique is used to produce pulsed quantum frequency combs. Moreover, we present how the quantum states can be coherently manipulated using standard telecommunications…
Generalized Thru-Reflect-Line Calibration Technique for the Measurement of Multimodal Radiating Waveguides
2017
The objective of this letter is to extend the use of the generalized thru-reflect-line measurement technique to the case of a radiating multimodal rectangular waveguide aperture. Although this radiating aperture has been carefully studied from a theoretical point of view, the relevant experimental characterization has been limited to the case where the feeding waveguide is monomodal. In addition to theory, we also present experimental results that agree quite well with full-wave simulations, thereby fully validating the measurement technique.
Alignment-free sequence comparison using absent words
2018
Sequence comparison is a prerequisite to virtually all comparative genomic analyses. It is often realised by sequence alignment techniques, which are computationally expensive. This has led to increased research into alignment-free techniques, which are based on measures referring to the composition of sequences in terms of their constituent patterns. These measures, such as $q$-gram distance, are usually computed in time linear with respect to the length of the sequences. In this paper, we focus on the complementary idea: how two sequences can be efficiently compared based on information that does not occur in the sequences. A word is an {\em absent word} of some sequence if it does not oc…
Portable remote photoplethysmography device for monitoring of blood volume changes with high temporal resolution
2016
The compact remote photoplethysmography device for monitoring of blood volume pulsations from human skin were developed. The prototype device comprises electronics board with twelve circullary oriented bright near-infrared LED illuminators, which are precisely controlled, high-speed video camera and battery charging circuit. Device was tested in laboratory and could be used for non-contact monitoring of human blood volume changes in palm.
Quality enhancement of multispectral images for skin cancer optical diagnostics
2018
Melanoma is the least common but deadliest skin cancer, accounting for only about 1% of all cases, but is the cause of the vast majority of skin cancer death. In some parts of the world, especially among western countries, melanoma is becoming more common every year. The detection of melanoma in early stage can be helpful to cure it. Unfortunately, long ques and high prices for dermatology service can result in the skin cancer diagnosis at its later stage, thus increasing the risk of mortality for the patient. It is important to provide a non-invasive optical device for primary care physicians to help diagnose different skin malformation based on obtained optical images. Such device will be…
Consciousness is Quantum Computed Beyond the Limits of the Brain: A Perspective Conceived from Cases Studied for Hydranencephaly
2016
Hydranencephaly is a developmental malady, where the cerebral hemispheres of the brain are reduced partly or entirely too membranous sacs filled with cerebrospinal fluid. Infants with this malady are presumed to have reduced life expectancy with a survival of weeks to few years and which solely depends on care and fostering of these individuals. During their life span these individuals demonstrate behaviours that are termed “vegetative” by neuroscientists but can be comparable to the state of being “aware” or “conscious”. Based on the most simplified definition for consciousness i.e. “awareness” or “to be aware”, these individuals are undeniably aware of their existence and therefore should…
Noninvasive optical diagnostics of enhanced green fluorescent protein expression in skeletal muscle for comparison of electroporation and sonoporatio…
2015
We highlight the options available for noninvasive optical diagnostics of reporter gene expression in mouse tibialis cranialis muscle. An in vivo multispectral imaging technique combined with fluorescence spectroscopy point measurements has been used for the transcutaneous detection of enhanced green fluorescent protein (EGFP) expression, providing information on location and duration of EGFP expression and allowing quantification of EGFP expression levels. For EGFP coding plasmid (pEGFP-Nuc Vector, 10 μg/50 ml 10 μg/50 ml ) transfection, we used electroporation or ultrasound enhanced microbubble cavitation [sonoporation (SP)]. The transcutaneous EGFP fluorescence in live mice was monit…
Effect of contact lens surface properties on comfort, tear stability and ocular physiology.
2018
Aim: Retrospective analysis of different contact lens wearing groups suggests lens surface lubricity is the main factor influencing contact lens comfort. However, the examined commercially available contact lenses differ in material and design as well as surface properties. Hence this study isolates the contribution of lens surface properties using an ultra-thin coating technology. Methods: Nineteen habitual contact lens wearers (21.6. ±. 1.7years) wore formofilcon B soft monthly disposable contact lenses with and without coating technology modified surface properties for a month each in a randomised double-masked cross-over study. Objective non-invasive: breakup time (NIKBUT), NIKBUT avera…
FRET-based method for evaluation of the efficiency of reversible and irreversible sonoporation.
2017
It is widely known that not all of the treated cells survive after introduction of exogenous molecules via any physical method. Therefore, it is important to develop methods that would allow simultaneous evaluation of both molecular delivery efficiency and cell viability. This study presents Forster resonance energy transfer (FRET)-based method that allows molecular transfer and cell viability evaluation in a single measurement by employing two common fluorescent dyes, namely, ethidium bromide and trypan blue. The method has been validated using cell sonoporation. The FRET-based method allows the efficiency evaluation of both reversible and irreversible sonoporation in a single experiment. …