Search results for "Option"
showing 10 items of 345 documents
A real options based model to select a balanced R&D portfolio
2011
The R&D process in the pharmaceutical industry has a long and dynamic life then it is an ideal field of application for ROA. Actually, ROA implementation, as widely demonstrated in literature, is narrowed to very limited cases because its perceived complexity. This research wants to suggest a simplified method, respect the ones available in literature, that could foster the use of ROA: we built up an integer linear programming model, based on a model available in literature, useful for selecting a balanced R&D portfolio from a set of candidate drugs. The model has been tested through a case study.
An affordable way to implement real options to select optimal R&D portfolio
2011
Real option Analysis (ROA) is acknowledged as a powerful tool to evaluate uncertain projects whose uncertainty depends heavily on alternatives available along the project life. The R&D process in the pharmaceutical industry has a long and dynamic life then it is an ideal field of application for ROA. Actually, ROA implementation, as widely demonstrated in literature, is narrowed to very limited cases because its perceived complexity. This research wants to suggest a simplified method, respect the ones available in literature, that could foster the use of ROA: we built up an integer linear programming model, based on a model available in literature, useful for selecting the optimal R&D produ…
A real options based support system to open innovation
2012
Pharmaceutical R&D process (PR&DP) has been deeply investigated by different streams of literature; the interest is due to the strategic implication of the related decisions undertaken. The PR&DP has been revolutionised by the biotech advent and as a consequence R&D managers cannot avoid to consider Open Innovation paradigm during this decision process. Starting from a Real Option optimization model available in literature, the paper aims at proposing a decision support system (DSS) able to suggest the candidate products to be included in the best R&D portfolio varying input parameters (resilient products), to provide a products Pareto analysis that aims at individuating the products for wh…
EVALUATING R&D ALLIANCES UNDER UNCERTAINTY: A REAL OPTIONS APPROACH
Pricing Reinsurance Contracts
2011
Pricing and hedging insurance contracts is hard to perform if we subscribe to the hypotheses of the celebrated Black and Scholes model. Incomplete market models allow for the relaxation of hypotheses that are unrealistic for insurance and reinsurance contracts. One such assumption is the tradeability of the underlying asset. To overcome this drawback, we propose in this chapter a stochastic programming model leading to a superhedging portfolio whose final value is at least equal to the insurance final liability. A simple model extension, furthermore, is shown to be sufficient to determine an optimal reinsurance protection for the insurer: we propose a conditional value at risk (VaR) model p…
Guías EAU sobre incontinencia urinaria
2011
Contexto: Las primeras directrices sobre incontinencia de la European Association of Urology (EAU) se publicaron en 2001. Dichas directrices se han actualizado con regularidad en los últimos años. Objetivo: El objetivo de este artículo es ofrecer un resumen de la actualización de las directrices sobre incontinencia urinaria (IU) de la EAU realizada en 2009. Recogida de evidencias: El comité de trabajo de la EAU formó parte de la IV Consulta Internacional sobre Incontinencia (ICI) y, con permiso de la ICI, llevó a cabo la extracción de la información de relevancia. La metodología de la IV ICI consistió en una amplia revisión de la literatura por parte de expertos internacionales y en la crea…
Determining the appropriate timing of the next forest inventory: incorporating forest owner risk preferences and the uncertainty of forest data quali…
2017
Key message The timing to conduct new forest inventories should be based on the requirements of the decision maker. Importance should be placed on the objectives of the decision maker and his/her risk preferences related to those objectives. Context The appropriate use of pertinent and available information is paramount in any decision-making process. Within forestry, a new forest inventory is typically conducted prior to creating a forest management plan. The acquisition of new forest inventory data is justified by the simple statement of “good decisions require good data.” Aims By integrating potential risk preferences, we examine the specific needs to collect new forest information. Meth…
Incidence du passage obligatoire aux normes comptables IAS / IFRS sur le risque d'instabilité bancaire
2011
In this thesis, we study the economic consequences, in terms of instability, of the mandatory IAS/IFRS adoption in the banking industry. The thesis is organized as follows. In a first part (Chapter I), we develop a theoretical framework whose purpose is to understand the mechanisms through which the mandatory IAS/IFRS adoption by banks may influence the probability of occurrence of a banking crisis. At this stage, we show that several arguments, derived from the contractual and informational perspectives of accounting, can be mobilized in order to justify the hypothesis that the mandatory IAS/IFRS adoption has a positive or a negative influence on banking stability. The second part of the t…
The Continued Innovation-Decision Process : A Case Study of Continued Adoption of Robotic Process Automation
2022
Robotic Process Automation (RPA) originally entered the field of information systems as one of those disruptive innovations that will, among other automation solutions, have a profound effect on job descriptions and work itself in near future. One of the sectors that will be revolutionized – and are in fact already changing – are financial and human resource (HR) services, such as accounting, billing, and payroll services. According to statistics, Finnish companies operating on the administrative and support services sector make little use of service robots. Companies that have initially adopted the technology do not necessary reach its full potential. We explore what factors create challen…
Optional Sampling Theorems
2020
In Chapter 9 we saw that martingales are transformed into martingales if we apply certain admissible gambling strategies. In this chapter, we establish a similar stability property for martingales that are stopped at a random time (optional sampling and optional stopping). In order also to obtain these results for submartingales and supermartingales, in the first section, we start with a decomposition theorem for adapted processes. We show the optional sampling and optional stopping theorems in the second section. The chapter finishes with the investigation of random stopping times with an infinite time horizon.