Search results for "Orbitrap"
showing 4 items of 74 documents
Retrospective analysis of pesticide metabolites in urine using liquid chromatography coupled to high-resolution mass spectrometry
2016
Abstract A comprehensive retrospective analysis of pesticide metabolites in urine was developed, using liquid chromatography coupled to Orbitrap high-resolution mass spectrometry (UHPLC-HRMS) that includes both post-run target (suspect screening) and non-target screening. An accurate-mass database comprising 263 pesticide metabolites was built and used for the post-run screening analysis. For non-target analysis, a “fragmentation-degradation” relationship strategy was selected. The proposed methodology was applied to 49 real urine samples from pregnant women. In the post-target analysis 26 pesticide metabolites were tentatively identified, 8 of which (2-diethylamino-6-methyl-pyrimidinol; 3-…
UHPLC-Orbitrap mass spectrometric characterization of organic aerosol from a central European city (Mainz, Germany) and a Chinese megacity (Beijing)
2018
Abstract Fine urban aerosol particles with aerodynamic equivalent dimeter ≤2.5 μm (PM2.5) were collected in Mainz (a city within the Rhine-Main area, the third largest metropolitan region in Germany) and Beijing (Chinese megacity). A solvent mixture of acetonitrile-water was used to extract the organic aerosol fraction (OA) from the particle samples. The extracts were analyzed by an ultrahigh resolution mass spectrometer (UHRMS) Orbitrap coupled with ultra-high-performance liquid chromatography (UHPLC) both in the negative and positive ion mode. The number of compounds observed in Beijing is a factor of 2–10 higher compared to Mainz. The clear differences on chemical composition of OA in th…
Colon Bioaccessibility under In Vitro Gastrointestinal Digestion of Different Coffee Brews Chemically Profiled through UHPLC-Q-Orbitrap HRMS
2021
Coffee represents one of the most traditionally consumed beverages worldwide, containing a broad range of human health&ndash
Análisis de antibióticos en alimentos de origen animal, agua de bebida para animales y piensos por cromatografía líquida de alta resolución acoplada …
2022
La utilización de agentes antimicrobianos en producción animal es uno de los principales riesgos para la salud debido a su potencial presencia como residuos en los alimentos en cualquier etapa de la cadena alimentaria. Según datos de la Agencia Europea de Medicamento, España es uno de los países en que las ventas de agentes antimicrobianos para animales productores de alimentos son más elevadas. Los principales efectos adversos producidos por los antibióticos son reacciones alérgicas, destrucción de la microbiota presente en el tracto gastrointestinal y el aumento de la selectividad de bacterias multiresistentes o producción de resistencias antimicrobianas. Actualmente, la resistencia a los…