Search results for "Organometallic Chemistry"

showing 10 items of 122 documents

Studies on DNA interaction of organotin(IV) complexes of meso-tetra(4-sulfonatophenyl)porphine that show cellular activity.

2016

PubMedID: 27393277 The interaction of the diorgano- and triorganotin(IV) derivatives of meso-tetra-(4-sulfonatophenyl)porphine (Me2Sn)2TPPS, (Bu2Sn)2TPPS, (Me3Sn)4TPPS and (Bu3Sn)4TPPS to natural DNA was analysed (together with free meso-tetra-(4-sulfonatophenyl)porphine (TPPS4 -) for comparison purposes). Particular attention was paid to (Bu3Sn)4TPPS, a species that shows significant cellular action. Preliminary tests were done on the solution properties of the organotin(IV) compounds (pKA and possible self-aggregation). Spectrophotometric and spectrofluorometric experiments showed that all the investigated organotin(IV) derivatives strongly interact with DNA, the binding energy depending …

Steric effectsCellular activityOrganometallic compounds External binding Negative porphyrins Aggregation ViscosityNegative porphyrinsPorphyrinsStereochemistryBinding energyDna interactionOrganometallic compounds010402 general chemistry01 natural sciencesMedicinal chemistryBiochemistryInorganic Chemistrychemistry.chemical_compoundAggregationmetal complexequilibrium constantDNA conformation changescomplex formationOrganotin CompoundsHumansDNA bindingEquilibrium constantGroup 2 organometallic chemistrybiology010405 organic chemistryViscosityDNAbiology.organism_classificationExternal binding0104 chemical sciencesAggregation External binding Negative porphyrins Organometallic compounds Viscosity Biochemistry Inorganic Chemistry metal complex equilibrium constant DNA conformation changes DNA binding complex formationchemistrySettore CHIM/03 - Chimica Generale E InorganicaA549 CellsTetraNucleic Acid ConformationDNAJournal of inorganic biochemistry
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Potentiometric study of the formation of hydroxo complexes of [Cu(terpy)]2+. Synthesis and crystal structure of [Cu(terpy) (H2O)](CF3SO3)2

1992

Two complexes of formula [Cu(terpy)(H2O)](CF3SO3)2 (1) and [Cu(terpy)(OH)]BPh4 (2) (terpy=2,2′∶6′,2″-terpyridine and BPh4=tetraphenylborate anion) have been synthesized and characterized by spectroscopic techniques. The x-ray crystal structure of (1) has been determined by x-ray diffraction. The structure is made up of [Cu(terpy)(H2O)]2+ mononuclear cations plus semi-coordinated CF3SO3 − anions. The coordination geometry around the copper atom is approximately elongated tetragonal octahedral. The oxygen atom of water and the three nitrogen atoms of terpy occupy the equatorial sites whereas the apical ones are filled by trifluoromethanesulphonate oxygen atoms. The formation of hydroxo comple…

TetraphenylborateChemistryStereochemistryMetals and AlloysCrystal structureInorganic ChemistryCrystallographychemistry.chemical_compoundOctahedronX-ray crystallographyMaterials ChemistryMoleculeTerpyridineOrganometallic chemistryCoordination geometryTransition Metal Chemistry
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Complexes of organometallic compounds

1972

Abstract The configurations of (CH 3 ) 3 PbNCS, (C 6 H 5 ) 3 PbNCS, (C 6 H 5 ) 2 Pb(NCS) 2 , (C 6 H 5 ) 3 Pb(NCS) 2 − and (C 6 H 5 ) 2 Pb(NCS) 4 2− have been investigated in the solid and (except for the insoluble diphenyl derivative) in solution. From infrared spectroscopy it is deduced that the compounds are isothiocyanates in both states, and there is evidence for a polymeric nature of the solid neutral species involving bridging through NCS. PMR and osmometric investigations show that five-coordinate species (CH 3 ) 3 Pb(NCS)·(CH 3 ) 2 CO are present in acetone solution. Possible configurations are discussed.

ThiocyanateStereochemistryOrganic ChemistryInfrared spectroscopyBiochemistryMedicinal chemistryInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryAcetonePhysical and Theoretical ChemistryDerivative (chemistry)Group 2 organometallic chemistryJournal of Organometallic Chemistry
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Complexes of organometallic compounds

1966

Abstract The compounds (C2H5)2PbCl2, (C2H5)3PbCl and PbCl2 were studied by paper electrophoresis in aqueous LiCl solutions of various molarities. Determination was made of the formation of chloride complexes in which the electric charge was a function of ligand concentration in the solution. From the results of these experiments, and from a comparative examination of anion exchange data obtained in previous researches, useful information is obtained for determining the ligand concentrations relative to the preponderance of cationic, neutral and anionic complexes in the aqueous solutions. From this information it is possible to assume (C2H5)2PbCl42− and (C2H5)3PbCl32− as the fully coordinate…

TineInorganic chemistryHalideElectrolytePaper electrophoresisChlorideBiochemistryAnalytical ChemistryInorganic Chemistrychemistry.chemical_compoundPolymer chemistrymedicineMaterials ChemistryPhysical and Theoretical ChemistryGroup 2 organometallic chemistryAqueous solutionChromatographyIon exchangeLigandOrganic ChemistryCationic polymerizationGeneral MedicineElectrophoresisPaper chromatographychemistryFluoridemedicine.drugJournal of Chromatography A
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Titanium Complexes Stabilized by a Sulfur‐Bridged Chelating Bis(aryloxo) Ligand as Active Catalysts for Olefin Polymerization

2004

The mixed-ligand complexes [Ti2(μ-OR)2(OR)2(κ3-tbop)2] (1a) for R = Me and (1b) R = Et were prepared by the reaction of Ti(OR)4 and H2tbop {H2tbop = 2,2′-thiobis[4-(1,1,3,3-tetramethylbutyl)phenol]} in methanol. Treatment of 1a and 1b with AlMe3 led to the substitution of terminal alkoxy groups to create the organometallic compounds [Ti2(μ-OR)2(κ3-tbop)2(Me)2] (2a) for R = Me and (2b) for R = Et. Controlled hydrolysis of 2b causes the evolution of methane and the formation of the titanoxane compounds [{Ti2(μ-OEt)2(κ3-tbop)2}2(μ-O)2]·2CH2Cl2 (3). Structures of 1a, 1b, 2a, 2b, and 3 were confirmed by NMR spectroscopy; 1b and 3 were further investigated with X-ray crystallography. Compounds 1a…

TitaniumEthyleneLigandSONuclear magnetic resonance spectroscopyCatalysisPolymerizationInorganic Chemistrychemistry.chemical_compoundO ligandschemistryPolymerizationPolymer chemistryAlkoxy groupChelationX‐ray diffractionGroup 2 organometallic chemistryAluminumEuropean Journal of Inorganic Chemistry
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Sulfur Dioxide Oxidation Catalyzed by Photosensitized Ytterbium Diphthalocyanine

2008

Oxidation of SO2 into SO3 was found effectively catalyzed by photosensitized ytterbium diphthalocyanine, YbPc2 (Pc = phthalocyanine ligand, C32H16N8) when performed in air-saturated dimethylformamide (DMF) solution at 20 °C. The process follows according to a multi-step complex mechanism involving chemical induction as its driving force. Excitation energy of the sandwich molecular system in YbPc2 is used to promote the reaction by creating a reactive intermediate form of the ytterbium complex hosting up to eight SO2 molecules. The conversion of SO2 proved complete.

YtterbiumUV–Vis spectroscopyChemistryReactive intermediateExcited stateschemistry.chemical_elementHomogeneous catalysisGeneral ChemistryPhotochemistryHomogeneous catalysisCatalysisCatalysischemistry.chemical_compoundSulfur dioxidePhthalocyanineDimethylformamideMoleculeYtterbium diphthalocyaninePhotosensitizationOrganometallic chemistryCatalysis Letters
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Zirconium & Hafnium: Organometallic ChemistryBased in part on the article Zirconium & Hafnium: Organometallic Chemistry by Bernard Gautheron,…

2006

This review considers the main aspects of organometallic chemistry of zirconium and hafnium during the last 10 years. It is complementary to the first edition of Encyclopedia of Inorganic Chemistry. The material is presented in two major parts divided in five and three sections respectively. The first part is devoted to syntheses: the first section, by far the largest, covers in a systematic manner bis and mono cyclopentadienyl complexes with +4, +3, and +2 oxidation states and more especially constrained-geometry (CG) complexes, cationic complexes, and anionic or zwitterionic 18-electron complexes; unusual coordination geometries at carbon stabilized by group 4 metallocenes are presented i…

ZirconiumChemistryEnantioselective synthesisCationic polymerizationchemistry.chemical_elementHafniumCatalysischemistry.chemical_compoundCyclopentadienyl complexPolymerizationPolymer chemistryOrganic chemistryOrganic synthesisOrganometallic chemistry
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Fluorescent organometallic complexes : when the photovoltaic leads to theranostics

2013

The goal of my PhD thesis was to synthesize new molecules, which give access to fluorescentorganometallic complexes with interesting properties for photovoltaic and theranostic. In thisproject, several main points have been studied.The first part of this manuscript concerns the synthesis of new metallocene and metalloporphyrinsbasedorganometallic complexes to the design of solar cells. After a short introduction, wepresented the synthesis of titanium complexes and metalloporphyrins in the first chapter. Inparticular, we described the synthesis of model compounds and the difficulties encountered duringthe transition to porphyrin derivatives. However, in view of results obtained and opportuni…

[CHIM.INOR] Chemical Sciences/Inorganic chemistryPorphyrinsThéranostiqueAnticancéreuxChimie organométalliqueCytotoxicity studiesOptical imagingChimie de coordinationCoordination chemistryPhotophysicsOrganometallic chemistryBODIPYsTheranosticPorphyrinesImagerie optiquePhotophysiqueEtudes de cytotoxicitéThérapieTherapyCancer
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200 Years of Lithium and 100 Years of Organolithium Chemistry

2018

The element lithium has been discovered 200 years ago. Due to its unique properties it has emerged to play a vital role in industry, esp. for energy storage, and lithium-based products and processes support sustainable technological developments. In addition to the many uses of lithium in its inorganic forms, lithium has a rich organometallic chemistry. The development of organometallic chemistry has been hindered by synthetic problems from the start. When Wilhelm Schlenk developed the basic principles to handle and synthesize air- and moisture-sensitive compounds, the road was open to further developments. After more information was available about the stability and solubility of such comp…

chemistry.chemical_classification010405 organic chemistrychemistry.chemical_elementNanotechnology010402 general chemistryAlkali metal01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundchemistryLithiumOrganometallic chemistryAlkylGroup 2 organometallic chemistryZeitschrift für anorganische und allgemeine Chemie
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Compounds of molybdenum(VI) with aspartic acid: A spectrophotometric and potentiometric study of the formation and interconversion equilibria in aque…

1990

Addition of Na2MoO4 to an excess of aspartic acid (AspH2) can produce any of four different complexes depending on the pH, namely [MoO3(Asp)]2−, [Mo2O5(Asp)2]2−, [Mo2O4(OH)(Asp)2]− and [Mo2O4(Asp)2]. The ranges of formation of these species with pH, the number of equivalents of acid necessary for their formation, and their stoichiometries, condensation degrees and stability constants, have been calculated by potentiometric and spectrophotometric techniques. The aspartic acid acts as a tridentate ligand in all cases.

chemistry.chemical_classificationAqueous solutionChemistryInorganic chemistryPotentiometric titrationMetals and Alloyschemistry.chemical_elementMedicinal chemistryCatalysisInorganic Chemistrychemistry.chemical_compoundDicarboxylic acidMolybdenumAspartic acidMaterials ChemistryChemical equilibriumOrganometallic chemistryTransition Metal Chemistry
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