Search results for "Osteon"
showing 10 items of 236 documents
Bisphosphonate treatment and dental implants: A systematic review
2015
Background To analyze articles that studied patients submitted to diphosphonates therapy and who received dental implants before, during or after bisphosphonate (BP) treatment, compared to healthy patients, analyzing the increase of failure and loss of implants or bisphosphonate related osteonecrosis of the jaw (BRONJ) incidence. Material and Methods The Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement was used in this study. The clinical question in “PICO” format was: In patients under bisphosphonate therapy, do dental implants placement, compared to healthy patients, increase the failure and loss of implants or bisphosphonate related osteonecrosis of t…
Dental implants in patients treated with oral bisphosphonates. A bibliographic review
2010
Bisphosphonates inhibit bone resorption and are used to treat a range of pathologies, including Paget disease, osteoporosis, multiple myeloma and metastases associated with breast or prostate cancer. At present, there is no effective treatment for bisphosphonate induced osteonecrosis, so prevention is extremely important. Since quality of life deteriorates for those suffering osteonecrosis, maximum precautions should be taken with patients at risk, and especially whenever oral surgery, including dental implant placement, is contemplated. Dentists and oral or maxillofacial surgeons must keep up to date with the latest approaches to prevention, particularly when treating patients who are pres…
Proposal for a preventive protocol for medication-related osteonecrosis of the jaw.
2021
Background Medication-related osteonecrosis of the jaw (MRONJ) is a severe adverse reaction experienced by some patients exposed to certain drugs (antiresorptives such as bisphosphonates or denosumab, and antiangiogenic drugs). From a review of the literature it appears that there is no uniform criterion when selecting preventive measures; these vary according to author. Likewise, the measures recommended are usually general, so that in few cases they result in specific actions to be applied depending on the different variables involved such as the type of drug used, the duration of its application, the underlying pathology, the presence or absence of risk factors, etc. The aim of this stud…
Application of Ozone Therapy in the Conservative Surgical Treatment of Osteonecrosis of the Jaw: Preliminary Results
2019
The main goals of the management of osteonecrosis of the jaw (ONJ) are to slow the progressionof the disease and, when it is achievable, to remove all the necrotic bone promoting the tissues’healing [...]
Estudio clínico, radiográfico y plasmático de la osteonecrosis de los maxilares por bisfosfonatos en un grupo de183 pacientes
2016
Osteonecrosis of the jaw is a particular form of chronic osteomyelitis caused by bisphosphonates (BF) or by other pharmacological or anti-angiogenic drugs. The BF are potent drugs inhibitors of osteoclasts by exerting a strong interaction with these cells, producing a sharp decrease of bone resorption. Objectives: To analyse clinical and radiologic characteristics as well as differences in the plasma levels of the Activation Nuclear Kappa receptor ligand (RANKL) and of osteoprotegerin (OPG) in a group of patients with osteonecrosis and compared to healthy controls. In addition, within the Group of patients with osteonecrosis maxillary study if there is relationship between plasma levels of …
Mucopolysaccharidoses and other lysosomal storage diseases.
2013
Mucopolysaccharidosis and other lysosomal storage diseases are rare, chronic, and progressive inherited diseases caused by a deficit of lysosomal enzymes. Patients are affected by a wide variety of symptoms. For some lysosomal storage diseases, effective treatments to arrest disease progression, or slow the pathologic process, and increase patient life expectancy are available or being developed. Timely diagnosis is crucial. Rheumatologists, orthopedics, and neurologists are commonly consulted due to unspecific musculoskeletal signs and symptoms. Pain, stiffness, contractures of joints in absence of clinical signs of inflammation, bone pain or abnormalities, osteopenia, osteonecrosis, secon…
Combined orthodontic-surgical management of an impacted maxillary canine in a pediatric patient at risk of osteonecrosis of the jaw: preliminary resu…
2019
Aspetti radiologici nell'osteonecrosi dei mascellari da bifosfonati e proposta di una classificazione radiologica in funzione dell'evoluzione clinica.
2011
CAPITOLO I. OSTEONECROSI DELLE OSSA MASCELLARI (ONJ) FARMACO-RELATA
2020
Si definisce osteonecrosi delle ossa mascellari associata a bisfo- sfonati e/o altri farmaci una “reazione avversa farmaco-correlata, caratterizzata dalla progressiva distruzione e necrosi dell’osso mandibolare e/o mascellare di soggetti esposti al trattamento con farmaci per cui sia accertato un aumentato rischio di malat- tia, in assenza di un pregresso trattamento radiante”. In Tabella. 1.1 sono riportati i relativi criteri di inclusione, di esclusione e di dubbio.
LA GESTIONE ODONTOIATRICA DEL PAZIENTE CHE ASSUMERÀ O ASSUME FARMACI ONJ-RELATI
2020
L’osteonecrosi delle ossa mascellari (ONJ) farmaco-relata è stata de- finita nel capitolo I come “una reazione avversa farmaco-correlata, caratterizzata dalla progressiva distruzione e necrosi dell’osso man- dibolare e/o mascellare di soggetti esposti al trattamento con farmaci per cui sia accertato un aumentato rischio di malattia, in assenza di un pregresso trattamento radiante”1. Tale definizione sottolinea la consapevolezza di uno stato di allerta e di vigilanza sui fattori di ri- schio associati alla patologia, con la possibile progressiva inclusione di nuove popolazioni di soggetti potenzialmente a rischio, e in linea con la continua evoluzione delle conoscenze scientifiche in materia…