Search results for "Osteon"

Interventions for treating osteonecrosis of the jaw stage III: may conservative surgical management be a viable option?

2018

Bisphosphonates and Oral Pathology II. Osteonecrosis of the jaws : Review of the literature before 2005

2006

Bisphosphonates are bone-turnover modulating drugs which are used in the management of a number of bone diseases ranging from osteoporosis to neoplasic pathology-associated osteolysis. In the last years a number of cases of osteonecrosis of the jaws associated with these drugs have been reported. In this review we analyze the cases published in the literature indexed from 2003 to December 2005. During this period 246 cases were reported, being more frequently associated with women in the sixth decade of life. More frequently associated bisphosphonates were the nitrogenated bisphosphonates (pamidronate, zolendronic acid) and the most common oral antecedent was a dental extraction. Neverthele…

Analisi morfometrica computerizzata delle variazioni strutturali della diafisi di ossa lunghe umane in rapporto all'età.

1992

The authors studied the micro - structural changes of aging long bones. The results show: an increase in the number of the osteons; a sensible decrease in their sectional area; a disappearance of the outer fundamental system until the sixth decade, which undergoes no significant changes afterwards. Whereas the area of the haversian canals and the percentage of the haversian system undergo no significant changes. The data suggest that the skeletal remodeling tends to keep constant, during the lfetime, the quota of the haversian system and the relation between the latter and the interstital system, through an increase in numebr of the osteons which involves a decrease in their size. On the ot…

Estrés oxidativo y su valor pronóstico en osteonecrosis idiopática de cabeza femoral

2015

La osteonecrosis no traumática y aséptica de cabeza femoral es una patología que se desarrolla como consecuencia de la disminución de aporte sanguíneo a la cabeza femoral, cuya causa no está relacionada con un proceso traumático o infeccioso: resulta en una alteración de la microcirculación, el subsecuente colapso de la cabeza femoral y la rápida destrucción de la articulación de la cadera. Es una patología que afecta a una población de entre 30-50 años suponiendo una afectación de la vida laboral y social y una de las principales causas de artroplastia total de cadera y de revisiones de esta cirugía y suele ser bilateral hasta en un 75-80% de las ocasiones; razones todas que suponen un ele…

Challenges and Controversies in the Diagnosis of MRONJ

2019

Medication-related osteonecrosis of the jaw (MRONJ) is a relatively rare but potentially seriousand debilitating complication [...]

Osteonecrosis of the jaw as an adverse bisphosphonate event: Three cases of bone metastatic prostate cancer patients treated with zoledronic acid

2007

Bisphosphonates offer a significant improvement in the quality of life for cancer patients; these potent inhibitors of bone resorption have been shown to markedly reduce the morbidity frequently resulting from bone metastases. Despite the success of bisphosphonates as therapeutic agents, however, toxicity in the form of osteonecrosis of the jaw (ONJ) is a rare complication whose incidence rate has climbed in recent years. ONJ is defined as an unexpected development of necrotic bone in the oral cavity, and is commonly associated with administration of the bisphosphonates Pamidronate and Zoledronate. Clinical features include local pain, soft-tissue swelling, and/or loose teeth; ONJ is also o…