Search results for "Other"

Tracas quotidiens des étudiants de première année de grandes écoles : liens avec la santé mentale perçue et la qualité de vie

2014

Resume L’entree dans une grande ecole, avec les nombreux changements occasionnes, peut etre consideree comme une situation potentiellement stressante. Nous avons donc souhaite identifier les difficultes rencontrees par les etudiants inscrits en premiere annee et leurs eventuelles repercussions sur leur sante et leur qualite de vie. Les resultats obtenus montrent que les tracas les plus frequents et les plus genants sont lies a la reussite dans les etudes (examens), a la gestion du temps (ne pas avoir le temps de faire ce que l’on voudrait faire), aux relations interpersonnelles (eloignement d’un etre cher) et a la sante (sommeil et reveil) avec des repercussions non negligeables sur leur sa…

Evaluación de la adaptación de los ítems de consumo del AUDIT para mejor el cribado de Binge Drinking en universitarios

2019

The strong presence of Binge Drinking (BD) amongst university students, as well as the consequences associated with the same and the changes taking place over recent years regarding its conceptualization make it necessary to examine the usefulness of screening instruments used to detect this drinking pattern. This study examines the usefulness of a briefer adaptation of the AUDIT proposed by Cortes, Gimenez, Motos, and Sancerni (2017a). College students self-administered the AUDIT, the revised items 2 and 3 (A2r and A3r), and completed a weekly self-report of their alcohol intake. BD was classified according to the amount consumed and the frequency of that consumption over the past six mont…

Estrés y drogadicción: una perspectiva actualizada para 2020

2020

The role of stress in addiction is complex. In this editorial we highlight the main issues of interest in the ongoing research in relation to drug addiction and stress from an up-to-date perspective. Thus, taking into account that several bibliographic reviews have been published recently on the subject, the aim of this editorial has been to  gather  updated information in order to point out future directions of research that could make a valuable contribution to the knowledge about addictions and the role that stress plays in them. Finally, we stress the need for interdisciplinary research that addresses stress and addictions by incorporating and integrating physical and psychosocial facto…

Patient Care Approach Using Nursing Theories - Comparative Analysis of Orem’s Self-Care Deficit Theory and Henderson’s Model

2020

Abstract Nursing theories have been developed to provide guidance in clinical practice, so their knowledge by nurses is mandatory in order to provide advanced nursing care. This paper presents the relationships between the concepts and major assumptions of Henderson’s model and Orem’s theory and then their comparative analysis. Both, Henderson’s model and Orem’s theory of self-care deficit have a major impact, internationally, in education and research, but also in nursing practice, as a result of which their knowledge can open a new perspective on care, especially in countries where they are not well enough known.

Occupational physical heaviness and sitting as predictors of mortality: a 26-year follow-up

2018

Two-qubit entanglement dynamics for two different non-Markovian environments

2009

We study the time behavior of entanglement between two noninteracting qubits each immersed in its own environment for two different non-Markovian conditions: a high-$Q$ cavity slightly off-resonant with the qubit transition frequency and a nonperfect photonic band-gap, respectively. We find that revivals and retardation of entanglement loss may occur by adjusting the cavity-qubit detuning, in the first case, while partial entanglement trapping occurs in non-ideal photonic-band gap.

'Palaeoshellomics' reveals the use of freshwater mother-of-pearl in prehistory

2019

The extensive use of mollusc shell as a versatile raw material is testament to its importance in prehistoric times. The consistent choice of certain species for different purposes, including the making of ornaments, is a direct representation of how humans viewed and exploited their environment. The necessary taxonomic information, however, is often impossible to obtain from objects that are small, heavily worked or degraded. Here we propose a novel biogeochemical approach to track the biological origin of prehistoric mollusc shell. We conducted an in-depth study of archaeological ornaments using microstructural, geochemical and biomolecular analyses, including ‘palaeoshellomics’, the first…

Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR).

2018

Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants. Here, we studied betulinic acid's cytotoxic activity against drug-resistant tumor cell lines. P-glycoprotein (MDR1/ABCB1) and BCRP (ABCG2) are known ATP-binding cassette (ABC) drug transporters that mediating MDR. ABCB5 is a close relative to ABCB1, which also mediates MDR. Constitutive activation of the EGF receptor is tightly linked to the development of chemotherapeutic resistance. BetA inhibited P-gp, BCRP, ABCB5 and mutation activated EGFR overexpressing cells with similar efficacy as their drug-sensitive parental counterparts. …

Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment

2018

Standard of care for cancer is commonly a combination of surgery with radiotherapy or chemoradiotherapy. However, in some advanced cancer patients this approach might still remaininefficient and may cause many side effects, including severe complications and even death. Oncolytic viruses exhibit different anti-cancer mechanisms compared with conventional therapies, allowing the possibility for improved effect in cancer therapy. Chemotherapeutics combined with oncolytic viruses exhibit stronger cytotoxic responses and oncolysis. Here, we have investigated the systemic delivery of the oncolytic adenovirus and paclitaxel encapsulated in extracellular vesicles (EV) formulation that, in vitro, s…

Hybrid Biopolymer and Lipid Nanoparticles with Improved Transfection Efficacy for mRNA

2020

Cells 9(9), 2034 (1-19) (2020). doi:10.3390/cells9092034