Search results for "Oxide"

Oleuropein protects against dextran sodium sulfate-induced chronic colitis in mice.

2013

The anti-inflammatory effect of oleuropein (1), the major phenolic secoiridoid in Olea europaea, was evaluated in an experimental model of chronic colitis in mice. Animals were exposed to four repeated cycles of dextran sodium sulfate in drinking water followed by a 7-day rest period. Animals receiving a standard diet supplemented with 0.25% of 1 (equivalent to 500 mg/kg/day) for 56 days exhibited a decrease of inflammatory symptoms, as reflected by improvement of disease activity index and histopathological changes. It was found that 1 decreased inflammatory cell recruitment and the release of inflammatory cytokines interleukin (IL)-1β and IL-6 with increased IL-10 levels in colon tissue. …

Host immune response to Cryptosporidium parvum infection

2010

Species of the genus Cryptosporidium are protozoan parasites (Apicomplexa) that cause gastroenteritis in animals and humans. Of these Cryptosporidium parvum and Cryptosporidium hominis are the major causative agents of human cryptosporidiosis. Whereas infection is self-limiting in the immunocompetent hosts, immunocompromised individuals develop a chronic, life-threatening disease. As specific therapeutic or preventive interventions are not yet available, better understanding of the immune response to the parasite is required. This minireview briefly summarizes the factors involved in the innate and acquired immune response in this pathogen-host interaction with an emphasis on more recent da…

Toxicological assessment of mesoporous silica particles in the nematode Caenorhabditis elegans

2018

[EN] Here we report the toxicological evaluation of mesoporous silica particles (MSPs) in the nematode C. elegans. Specifically, we have investigated the effect of bare micro- (M0) and nano-sized (N0) MSPs, and their corresponding functionalized particles with a starch derivative (Glu-N) (M1 and N1, respectively) on C. elegans ageing parameters. The toxicity of MSPs, their impact on C. elegans lifespan, movement capacity, progeny and ability to survive upon exposure to acute oxidative stress were assessed. This study demonstrated that both size particles assayed (M0 and N0), labeled with rhodamine and monitored through fluorescence microscopy, are ingested by the nematode. Moreover, toxicit…

Azobenzene Polyesters Used as Gate-Like Scaffolds in Nanoscopic Hybrid Systems

2012

The synthesis and characterisation of new capped silica mesoporous nanoparticles for on-command delivery applications is reported. Functional capped hybrid systems consist of MCM-41 nanoparticles functionalised on the external surface with polyesters bearing azobenzene derivatives and rhodamine¿B inside the mesopores. Two solid materials, Rh-PAzo8-S and Rh-PAzo6-S, containing two closely related polymers, PAzo8 and PAzo6, in the pore outlets have been prepared. Materials Rh-PAzo8-S and Rh-PAzo6-S showed an almost zero release in water due to steric hindrance imposed by the presence of anchored bulky polyesters, whereas a large delivery of the cargo was observed in the presence of an esteras…

Characterization of V-doped SnO2 nanoparticles at ambient and high pressures

2018

Nanoparticles of V-doped SnO2 with stoichiometry Sn1-xO2Vx (x = 0.05, 0.075, 0.125) have been synthesized by a co-precipitation method. Their structural, vibrational, and nuclear properties have been characterized by x-ray Diffraction, Transmission Electron Microscopy, Energy Dispersive x-ray Spectroscopy, Raman Spectroscopy, and Mössbauer Spectroscopy (with 119Sn probe) at ambient pressure. We also performed high-pressure synchrotron x-ray diffraction experiments. The structural behaviour was studied up to ∼10 GPa under quasi-hydrostatic conditions. It has been found that tin dioxide nanoparticles with V are more compressible than un-doped tin dioxide nanoparticles. Fil: Ferrari, S. Consej…

Metals Recovery from Waste Pickling Solutions by Reactive Precipitation

2021

Pickling is one of the most important steps in steel manufacturing industry. During the process, an acid reacts with the surface oxides causing metal ions accumulation in the pickling solution. Disposal of the waste acid represents a critical issue for the hot-dip galvanizing industry in terms of environmental damage and high costs. Recovering of the main products by using an integrated process, with the perspective of a circular approach, could minimize the wastewater production, leading to reinvigorate this industrial sector economy. In this context, recovery of the metal ions mainly present in the pickling solution, such as Fe and Zn, becomes a critical issue. In this work, the reactive …

FLEXIBLE ELECTRODE BASED ON GOLD NANOPARTICLES AND REDUCED GRAPHENE OXIDE FOR URIC ACID DETECTION USING LINEAR SWEEP VOLTAMMETRY

2021

In this work, an electrochemical sensor for uric acid determination is shown with a preliminary study for its validation in real samples (milk and urine). Uric acid can be electrochemically oxidized in aqueous solutions and thus it is possible to obtain electrochemical sensors for this chemical by means of this electrooxidation reaction. Indium tin oxide coated on flexible polyethylene terephthalate substrate, modified with reduced graphene oxide and gold nanoparticles by co-electrodeposition, was used. Electrodeposition was performed at -0.8V vs SCE for 200 s. All samples were characterized by electron scan microscopy and electron diffraction spectroscopy. A careful investigation on the ef…

ROLE OF NITRIC OXIDE/cGMP PATHWAY IN CANNABINOID MODULATION OF PAROXYSMAL PHENOMENA

Initial Preparation and Characterization of Single Step Fabricated Intermediate Temperature Solid Oxide Fuel Cells (IT-SOFC)

2013

In this study, facile tape casting process has been successfully carried out to fabricate an unit anode supported intermediate temperature solid oxide fuel cell (IT-SOFC) with four different layers: a composite cathode which is a mix of La0.6Sr0.4Co0.2Fe0.8O3 (LSCF48) and Gd0.1Ce0.9O1.9 (GDC10), GDC10 as thin electrolyte layer, NiO-GDC10 without pore former as thin anode functional layer (AFL), and anode support layer of NiO-GDC10 with carbon pore former. The multi-layer was sintered once to produce an unit planar cell. An OCV of 1.002 V at 500 °C, and maximum power density of 466 mW cm–2 at 648 °C are obtained. These results indicate negligible leakage of fuel through electrolyte. Furtherm…

The Innervation of Taste Buds in the Soft Palate and Circumvallate Papilla of the Rat as Revealed by the Zinc Iodide-Osmium Tetroxide Technique.

1998

The taste buds in the soft palate and the circumvallate papillae of the rat were investigated by the zinc iodide-osmium tetroxide technique. In addition, electron micrographs of taste buds stained with this method were presented for the first time. Differences in taste bud structures were found between the examined regions. The taste buds of the soft palate showed a complicated plexus of intragemmal nerve fibers. Some fibers exhibited terminal polymorphic swellings. Single branches could be traced close to the space of the taste pore. In the soft palate, the taste bud cells remained unstained, whereas in the circumvallate papillae of the tongue, a subpopulation of taste bud cells could be s…