Search results for "Oxime"

showing 10 items of 148 documents

Capillary column gas chromatographic identification of sugars in honey as trimethylsilyl derivatives.

1987

A method for identifying carbohydrates (mono-, di- and trisaccharides) in honey is presented. It is based on the separate preparation of both trimethylsilyl ethers and oxime trimethylsilyl ethers of the sugars followed by their gas chromatographic separation on a fused-silica capillary column coated with OV-101 using temperature programming. From the two chromatograms, the number of peaks given by each derivatized sugar, their relative retention times and peak-area ratios are used for identification. The identities of two unidentified trisaccharide peaks are considered. Quantitative applications to honey sugar analysis are discussed.

chemistry.chemical_classificationTrimethylsilyl CompoundsChromatographyChromatography GasTrimethylsilylOrganic ChemistryCarbohydratesTemperatureGeneral MedicineHoneyCarbohydrateOximeBiochemistryAnalytical Chemistrychemistry.chemical_compoundChromatographic separationchemistryCapillary columnOximesOrganic chemistryIndicators and ReagentsTrisaccharideGas chromatographySugarJournal of chromatography
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Synthesis, characterization and magnetic properties of mixed-valence iron complexes with 2-pyridyl oximes

2018

Two new mixed-valence iron complexes with 2-pyridyl oximes, [Fe(mpko)3Fe(H2O)2(NO3)](NO3)·2H2O (1) (mpko− = methyl(2-pyridyl)ketone oximate) and [{Fe(dpko)3}2Fe](ClO4)·4H2O (2) (dpko− = bis(2-pyridyl)ketone oximate), have been prepared by reaction of FeIII with mpkoH in methanol (1) and FeII with dpkoH in methanol/water (2). Dinuclear FeII(low-spin)FeIII(high-spin) and trinuclear FeII(low-spin)FeIII(high-spin)FeII(low-spin) cations are present in the crystal structure of 1 and 2, respectively. Intermolecular hydrogen bonds in 1 lead to weak antiferromagnetic interactions between pairs of neighboring FeIII centers, which allows observation of single-ion zero-field splitting effects.

chemistry.chemical_classificationValence (chemistry)Ketone010405 organic chemistryChemistryHydrogen bondIntermolecular forceCrystal structure010402 general chemistry01 natural sciences0104 chemical sciencesMethyl 2-pyridyl ketone oximechemistry.chemical_compoundCrystallographyMaterials ChemistryAntiferromagnetismMethanolPhysical and Theoretical Chemistry
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Über umsetzungen an poly-p-lithiumstyrol. 4. Mitt. Darstellung carbonylgruppenhaltiger derivate des polystyrols

1961

In Fortsetzung fruherer Arbeiten wird die Reaktivitat von Poly-p-lithiumstyrol gegenuber solchen Agenzien gepruft, die zur Bildung von carbonylgruppenhaltigen Verbindungen fuhren. Wahrend bei der Umsetzung mit Orthoameisensaureester nur vernetzte Polymere entstechen, last sich mit Dimethylformamid ein losliches Derivat des Polystyrols herstellen das p-standige Formylgruppen tragt. Die Reaktion mit Nitrilen liefert polymere Ketone; mit Acetophenon entsteht Poly-p-vinylacetophenon, das mit dem aus dem Monomeren durch Polymerisation erhaltenen Produkt verglichen wird. Mit Benzonitril erhalt man Poly-p-vinylbenzophenon. Die polymeren Ketone konnen in die Oxime ubergefuhrt werden, deren Sticksto…

chemistry.chemical_classificationchemistry.chemical_compoundBenzonitrileMonomerKetonechemistryPolymer chemistryBenzophenoneDimethylformamideReactivity (chemistry)OximeAcetophenoneDie Makromolekulare Chemie
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Cu(II), Ni(II) and Zn(II) mononuclear building blocks based on new polynucleating azomethine ligand : Synthesis and characterization

2017

Five new mononuclear complexes formed by the polynucleating ligand 2-[1-(3,5-dimethyl)pyrazolyl]-2-hydroxyimino-N′-[1-(2-pyridyl)ethylidene]acetohydrazide (HL): [Ni(L)(HL)]ClO4·2CH3OH (1), [Ni(L)2]·CH3OH (2), [Zn(L)(HL)]ClO4·2CH3OH (3), [Zn(L)2]·CH3OH (4) and [Cu(L)2]·CH3OH (5) were synthesized and characterized by elemental analysis, mass-spectrometry, IR-spectroscopy and X-ray analysis. The complexes reveal distorted octahedral N4O2 coordination arrangement formed by both protonated and deprotonated (1, 3) or two deprotonated ligand molecules (2, 4, 5). The presence of non-coordinated oxime and pyrazole groups resulted in the formation of extensive systems of hydrogen bonds in the crystal…

chemistry.chemical_classificationkemia010405 organic chemistryStereochemistryLigandHydrogen bondligandsProtonationliganditPyrazole010402 general chemistryOximechemistry01 natural sciencesMedicinal chemistry0104 chemical sciencesCoordination complexInorganic Chemistrychemistry.chemical_compoundDeprotonationchemistryMaterials ChemistryMoleculePhysical and Theoretical Chemistryta116
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Co(II)-mediated synthesis of 2-carbamimidoylbenzoates and isoindole-1,3-diaminates

2015

Abstract Phthalonitrile, acetoxime and cobalt(II) nitrate hexahydrate are combined in acetone with formation of stable and easy to handle Co(II) complex [Co{C6H4C(NH2)NC(ONCMe2)2}2](NO3)2 (1). Interaction of 1 with excess alcohols ROH (also used as solvents) and 2 equiv of (NH4)2S leads, in one-step, to alkyl 2-carbamimidoylbenzoate nitrates [C6H4COOR{2-C(NH2)2}]NO3 [R=CH3, C2H5, C3H7, CH(CH3)2]. Similarly, N1,N3-dialkyl-1H-isoindole-1,3-diaminate nitrates [C6H4C(NR′)NC(NR′)]NO3 [R=C3H7, C4H9, C(CH3)3, CH2CH2OH, CH2CH2SC2H5) can be directly produced from 1 by its reaction with 4 equiv of amines and 2 equiv of (NH4)2S in alcoholic media.

chemistry.chemical_classificationphthalonitrilesChemistryStereochemistrymetal assisted (mediated) synthesisOrganic Chemistrychemistry.chemical_elementN1oximesBiochemistryMedicinal chemistryPhthalonitrilechemistry.chemical_compoundNitrateDrug DiscoveryAcetone3-diaminatesIsoindoleCobaltta116alkyl 2-carbamimidoylbenzoatesN3-dialkyl-isoindole-1AlkylTetrahedron
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ChemInform Abstract: Palladium-Catalyzed Suzuki Carbonylative Reaction of α-Halomethyl Oxime Ethers: A Regioselective Route to Unsymmetrical 1,3-Oxyi…

2015

chemistry.chemical_compoundChemistryRegioselectivitychemistry.chemical_elementGeneral MedicineOximeMedicinal chemistryPalladiumCatalysisChemInform
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ChemInform Abstract: Aza-Henry Reaction of Isatin Ketimines with Methyl 4-Nitrobutyrate en Route to Spiro[piperidine-3,3′-oxindoles].

2016

A new enantioselective route to spiro[piperidine-3,3′-oxindoles] from isatin ketimines is described. The aza-Henry reaction of N-Boc-isatin ketimines with methyl 4-nitrobutyrate in the presence of a Ph2BOX-CuBr2 complex provided the corresponding nitro amino esters with good diastereoselectivity and excellent enantioselectivity (up to >99% ee). The aza-Henry adducts were transformed into spiro[piperidine-3,3′-oxindoles] after reduction of the nitro group to oxime, and cleavage of the N-Boc group and lactamisation.

chemistry.chemical_compoundNitroaldol reactionchemistryAmino estersIsatinNitroEnantioselective synthesisGeneral MedicinePiperidineOximeMedicinal chemistryAdductChemInform
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Aza-Henry Reaction of Isatin Ketimines with Methyl 4-Nitrobutyrate en Route to Spiro[piperidine-3,3′-oxindoles]

2015

A new enantioselective route to spiro[piperidine-3,3′-oxindoles] from isatin ketimines is described. The aza-Henry reaction of N-Boc-isatin ketimines with methyl 4-nitrobutyrate in the presence of a Ph2BOX-CuBr2 complex provided the corresponding nitro amino esters with good diastereoselectivity and excellent enantioselectivity (up to >99% ee). The aza-Henry adducts were transformed into spiro[piperidine-3,3′-oxindoles] after reduction of the nitro group to oxime, and cleavage of the N-Boc group and lactamisation.

chemistry.chemical_compoundNucleophilic additionNitroaldol reactionchemistryAmino estersStereochemistryIsatinNitroEnantioselective synthesisGeneral ChemistryPiperidineOximeAdvanced Synthesis & Catalysis
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Reaction Mechanism of an Intramolecular Oxime Transfer Reaction: A Computational Study

2014

Density functional theory (PBE0/def2-TZVPP) calculations in conjunction with a polarizable continuum model were used to assess the mechanism of the intramolecular oxime transfer reaction that leads to the formation of isoxazolines. Different diastereomers of the intermediates as well as different oximes (formaldehyde and acetone oxime) were considered. The computed reaction profile predicts the water-addition and -expulsion steps as the highest barriers along the pathway, a conclusion that is in line with the experimental evidence obtained previously for these reactions.

chemistry.chemical_compoundReaction mechanismchemistryIntramolecular forceOrganic ChemistryDiastereomerFormaldehydeDensity functional theoryPhotochemistryOximeta116Polarizable continuum modelAcetone oximeThe Journal of Organic Chemistry
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Palladium-Catalyzed Suzuki Carbonylative Reaction of α-Halomethyl Oxime Ethers: A Regioselective Route to Unsymmetrical 1,3-Oxyiminoketones

2014

chemistry.chemical_compoundReaction mechanismchemistryRegioselectivitychemistry.chemical_elementOrganic chemistryGeneral ChemistryOximeCarbonylationPalladiumCatalysisAdvanced Synthesis & Catalysis
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