Search results for "Oxyhemoglobin"

showing 5 items of 25 documents

Impact of Various Thermal Doses on the Oxygenation and Blood Flow in Malignant Tumors Upon Localized Hyperthermia

1984

Hyperthermia exhibits various direct cytocidal effects (Dickson, 1977; Overgaard, 1977; Suit, 1977). During heat treatment in vivo, several indirect mechanisms enhance the direct cell-killing capacity of hyperthermia. Therefore, the effective use of hyperthermia can overcome some of the well-known problems involved in modern radiation therapy at least in some malignant tumors.

Tissue temperatureHyperthermiabusiness.industrymedicine.medical_treatmentOxygenationBlood flowTumor Oxygenationmedicine.diseaseRadiation therapyIn vivoAnesthesiamedicinebusinessOxyhemoglobin saturation
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Dynamic properties of some β-chain mutant hemoglobins

1995

The thermal behavior of the Soret band relative to the carbonmonoxy derivatives of some beta-chain mutant hemoglobins is studied in the temperature range 300-10 K and compared to that of wild-type carbonmonoxy hemoglobin. The band profile at various temperatures is modeled as a Voigt function that accounts for homogeneous broadening and for the coupling with high- and low-frequency vibrational modes, while inhomogeneous broadening is taken into account with a gaussian distribution of purely electronic transition frequencies. The various contributions to the over-all bandwidth are singled out with this analysis and their temperature dependence, in turn, gives information on structural and dy…

Voigt profileCoupling constantBase SequenceChemistryProtein dynamicsMolecular Sequence DataAnharmonicityHemoglobin AHemeBiochemistryRecombinant ProteinsMolecular electronic transitionCold TemperatureCrystallographyCarboxyhemoglobinModels ChemicalSpectrophotometryStructural BiologyMolecular vibrationMutationMutagenesis Site-DirectedHomogeneous broadeningRotational–vibrational couplingMolecular BiologyProteins: Structure, Function, and Genetics
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Structure-dynamics-function relationships in Asian elephant (Elephas maximus) myoglobin. An optical spectroscopy and flash photolysis study on functi…

1993

In this work we report the thermal behavior (10–300 K) of the Soret band lineshape of deoxy and carbonmonoxy derivatives of Asian elephant (Elephas maximus) and horse myoglobins together with their carbon monoxide recombination kinetics after flash photolysis; the results are compared to analogous data relative to sperm whale myoglobin. The Soret band profile is modeled as a Voigt function that accounts for the coupling with high and low frequency vibrational modes, while inhomogeneous broadening is taken into account with suitable distributions of purely electronic transition frequencies. This analysis makes it possible to isolate the various contributions to the overall lineshape that; in…

Voigt profilePhotolysisMyoglobinProtein ConformationPhotodissociationElephantsAnalytical chemistryElectron Spin Resonance SpectroscopyBiophysicsSoft modesMolecular electronic transitionchemistry.chemical_compoundStructure-Activity RelationshipMyoglobinchemistryCarboxyhemoglobinChemical physicsSpectrophotometryMolecular vibrationFlash photolysisAnimalsThermodynamicsHorsesSpectroscopyResearch ArticleBiophysical Journal
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The determination of haemoglobin as cyanhaemiglobin or as alkaline haematin D-575. Comparison of method-related errors.

1989

In order to compare the accuracy of haemoglobin (Hb) determination methods, the commonly used cyanhaemiglobin (HiCN) method and the recently developed alkaline haematin D-575 (AHD) method (R. Zander, W. Lang & H. U. Wolf (1984) Clin. Chim. Acta 136, 83-93; H. U. Wolf, W. Lang & R. Zander (1984) Clin. Chim. Acta 136, 95-104) were tested with respect to method-related errors such as plasma, cell, and Hb errors. Both methods yield a series of more or less significant errors which generally lead to an overestimation of the Hb concentration in the order of 1%. However, in all three cases of plasma errors, i.e. normal plasma error, plasma error in lipaemic blood, and plasma error in bilirubinaemi…

educationBiochemistry (medical)Clinical BiochemistryErythrocyte MembraneAnalytical chemistryHyperlipidemiasGeneral MedicineBiologyHaematinRed blood cellchemistry.chemical_compoundHemoglobinsmedicine.anatomical_structurechemistryCarboxyhemoglobinPredictive Value of TestsBlood plasmamedicineLeukocytesDetermination methodsHumansHemoglobinFetal HemoglobinHyperbilirubinemiaJournal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie
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Sleep Disturbances in COPD are Associated with Heterogeneity of Airway Obstruction

2018

Individuals with Chronic Obstructive Pulmonary Disease (COPD) experience sleep disturbances due to the impact of respiratory symptoms on sleep quality. We explored whether sleep disturbances in COPD are linked to heterogeneity of airway constriction.The impact of breathing problems on sleep quality was measured in consecutive COPD outpatients with the COPD and Asthma Sleep Impact Scale (CASIS) questionnaire. Impulse oscillometry technique (IOS) was employed to assess heterogeneity of airway constriction. Subjects with a previous or concomitant diagnosis of asthma or obstructive sleep apnea (OSA) were excluded.Fifty COPD subjects (M/F 40/10; age: 71 +/- 8 yrs, Body Mass Index (BMI): 26.2 +/-…

sleep abnormalitieMaleSleep Wake DisordersPulmonary and Respiratory Medicinemedicine.medical_specialtyPulmonary diseaseCASISSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary Disease Chronic Obstructive03 medical and health sciences0302 clinical medicineForced Expiratory VolumeOscillometrySurveys and QuestionnairesInternal medicinemedicineCOPDHumansSleep Wake DisorderOximetry030212 general & internal medicineRespiratory systemOxyhemoglobinAgedIOSCOPDSleep qualitybusiness.industryMiddle AgedAirway obstructionmedicine.diseaseSleep in non-human animalsSleep abnormalitiesResidual Volume030228 respiratory systemOxyhemoglobinsCardiologyFemalebusinessHumanCOPD: Journal of Chronic Obstructive Pulmonary Disease
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