Search results for "PAM"
showing 10 items of 1768 documents
Modelo Barcelona y política cultural: usos y abusos de la cultura por parte de un modelo emprendedor de desarrollo local
2015
El Modelo Barcelona de desarrollo local ha sido intensamente debatido· Desde su inicio en los años ochenta hasta la actualidad, diversos autores han analizado sus características como modelo, destacado sus éxitos y también sus puntos débiles. No obstante, menos atención ha recibido la relación que existe entre el modelo de desarrollo local y el modelo de política cultural, a pesar de que Barcelona también es internacionalmente conocida por su dinamismo cultural. De manera habitual, este modelo de política cultural ha sido interpretado como un instrumento en la agenda de desarrollo local. El presente artículo mostrará, a partir de análisis de diversos casos ejemplares, que la política cultur…
Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothal…
2015
Endocannabinoids participate in the control of neurogenesis, neural cell death and gliosis. The pharmacological effect of the fatty acid amide hydrolase (FAAH) inhibitor URB597, which limits the endocannabinoid degradation, was investigated in the present study. Cell proliferation (phospho-H3(+) or BrdU(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (GFAP(+)), and microglia (Iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with URB597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). Repeated URB597 treatment increased the plasma levels of the N-acylethanolamine…
Measurement of the atmospheric ?µ energy spectrum from 100 GeV to 200 TeV with the ANTARES telescope
2013
Atmospheric neutrinos are produced during cascades initiated by the interaction of primary cosmic rays with air nuclei. In this paper, a measurement of the atmospheric energy spectrum in the energy range 0.1-200 TeV is presented, using data collected by the ANTARES underwater neutrino telescope from 2008 to 2011. Overall, the measured flux is similar to 25 % higher than predicted by the conventional neutrino flux, and compatible with the measurements reported in ice. The flux is compatible with a single power-law dependence with spectral index gamma (meas)=3.58 +/- 0.12. With the present statistics the contribution of prompt neutrinos cannot be established.
Search for muon neutrinos from gamma-ray bursts with the ANTARES neutrino telescope using 2008 to 2011 data
2013
Aims. We search for muon neutrinos in coincidence with GRBs with the ANTARES neutrino detector using data from the end of 2007 to 2011. Methods. Expected neutrino fluxes were calculated for each burst individually. The most recent numerical calculations of the spectra using the NeuCosmA code were employed, which include Monte Carlo simulations of the full underlying photohadronic interaction processes. The discovery probability for a selection of 296 GRBs in the given period was optimised using an extended maximum-likelihood strategy. Results. No significant excess over background is found in the data, and 90% confidence level upper limits are placed on the total expected flux according to …
Aerosol closure study by lidar, sun photometry, and airborne optical counters during DAMOCLES field campaign at El Arenosillo sounding station, Spain
2011
We present a comparison of aerosol properties derived from in situ and remote sensing instruments during DAMOCLES campaign, aimed at investigating the equivalence between the instrumentation and methodologies employed by several Spanish groups to study atmospheric aerosols at a regional background site. The complete set of instruments available during this closure experiment allowed collecting a valuable high-resolution aerosol measurement data set. The data set was augmented with airborne in situ measurements carried out in order to characterize aerosol particles during the midday of 29 June 2006. This work is focused on aerosol measurements using different techniques of high-quality instr…
Current and emerging developments in subseasonal to decadal prediction
2020
Weather and climate variations on subseasonal to decadal time scales can have enormous social, economic, and environmental impacts, making skillful predictions on these time scales a valuable tool for decision-makers. As such, there is a growing interest in the scientific, operational, and applications communities in developing forecasts to improve our foreknowledge of extreme events. On subseasonal to seasonal (S2S) time scales, these include high-impact meteorological events such as tropical cyclones, extratropical storms, floods, droughts, and heat and cold waves. On seasonal to decadal (S2D) time scales, while the focus broadly remains similar (e.g., on precipitation, surface and upper-…
The Influence of Land Surface Temperature in Evapotranspiration Estimated by the S-SEBI Model
2020
Evapotranspiration (ET) is one of the least understood components of the hydrological cycle. Its applications are varied, from agricultural, ecological and hydrological monitoring, to control of the evolution of climate change. The goal of this work was to analyze the influence that uncertainties in the estimate of land surface temperature (Ts) can cause on ET estimates by S-SEBI model in the Pampa biome area. Also, the specificities of native grassland of Pampa biome related to energy balance were analyzed. The results indicate that the daily evapotranspiration is higher when the pixel Ts is lower, which also shows the influence of land use on the variability of ET. The results demonstrate…
Involvement of purinergic nerves in the NANC inhibitory junction potentials in pigeon oesophageal smooth muscle.
2004
1. Electrical field stimulation (EFS) (0.5 ms in train of 2-32 Hz for 300 ms) in smooth muscle of pigeon oesophagus, in the presence of atropine (1 microm) and guanethidine (1 microm), elicited an inhibitory response consisting of a transient hyperpolarization (inhibitory junction potential, IJP) associated with muscle relaxation. 2. Sodium nitroprusside (SNP, 100 microm) induced hyperpolarization correlated to mechanical relaxation. 3. The nitric oxide (NO) synthase inhibitor N(omega)-nitro-l-arginine (from 0.1 to 100 microm) caused a concentration-dependent reduction of electromechanical response to EFS indicating a role for NO in this response. 4. Apamin (1 microm) reduced both IJP and r…
Non-adrenergic non-cholinergic nerve-mediated inhibitory control of pigeon oesophageal muscle.
1996
Pigeon oesophageal smooth muscle in vitro has spontaneous electromechanical activity. In the presence of atropine and guanethidine, electrical field stimulation evokes a transient TTX-sensitive response comprising inhibition of electric bursting activity and muscular relaxation. This NANC inhibitory response was analysed using the K+ channel blockers TEA and apamin, TEA perfusion (0.1-5 mM) induced a concentration-dependent reduction in amplitude of EFS-evoked relaxation. Responses to higher stimulation frequencies were more sensitive to TEA than those to lower ones. The maximum reduction in amplitude (29% of control) was obtained on 30 Hz EFS evoked responses during 5 mM TEA perfusion. In …
Cannabinoid CB1 receptor activation modulates spontaneous contractile activity in mouse ileal longitudinal muscle.
2007
The purpose of the present study was to examine whether cannabinoid receptor agonists influence spontaneous contractile activity of longitudinal muscle in mouse ileum in vitro. Isolated segments of mouse ileum displayed spontaneous contractions with an amplitude and frequency of about 300 mg and 30 cpm, respectively. The endocannabinoid anandamide (1-100 microM), the selective cannabinoid CB(1) receptor agonist, ACEA (0.1 microM-10 microM), but not the selective cannabinoid CB(2) receptor agonist, JWH 133 (0.1 microM-10 microM), reduced in a concentration-dependent manner the spontaneous mechanical activity. The inhibitory effect consisted in a decrease of the mean amplitude of longitudinal…