Search results for "PAM"
showing 10 items of 1768 documents
Reduced graphene oxide decorated with metals nanoparticles electrode as electrochemical sensor for dopamine
2019
Dopamine (DA) is one of the most important neurotransmitters that influences the processes that involve memory, sleep, mood, learning among others [1]. In fact, in the last years, dopamine concentration in human body fluids has been related to some neurodegenerative diseases, such as Parkinson and Alzheimer's diseases [2]. The possibility to have a bio-marker for these disease is of extreme importance because, disease related with dementia, are diagnosed when they are already developed and their management become almost impossible. The possibility to continuously monitor DA level in fluids, such as blood and urine, could accelerate the early diagnosis of these diseases. The principal analyt…
Pamatlīdzekļi un to grāmatvedības uzskaite un analīze pašvaldības SIA “VANGAŽU AVOTS”
2022
Maģistra darba temats ir “Pamatlīdzekļi un to grāmatvedības uzskaite un analīze Pašvaldības SIA “Vangažu avots””. Pamatlīdzekļu uzskaitei un analīzei ir būtiska nozīme uzņēmuma saimnieciskajā darbībā, jo no pareizas uzskaites un grāmatvedības politikas ir atkarīgs uzņēmuma finanšu rezultāts. PSIA “Vangažu avots” pastāv vairākas nepilnības pamatlīdzekļu uzskaitē. Maģistra darba mērķis ir pamatojoties uz pamatlīdzekļu uzskaites un analīzes teorētisko atziņu izpēti, izvērtēt PSIA “Vangažu avots” pamatlīdzekļu uzskaiti un izmantošanas efektivitāti un izstrādāt priekšlikumus pamatlīdzekļu uzskaites pilnveidošanai un nepilnību novēršanai. Maģistra darba izstrādes rezultātā autore konstatēja nepil…
Successive alkalinity producing system for the treatment of acid sulphate soil runoff: preliminary results of a field trial
2005
A successive alkalinity producing system (SAPS) has been investigated as a potential passive treatment option for acid, metal containing runoff from acid sulphate soil. A pilot-scale system was installed at an agricultural land site in Rintala embankment area in mid-western Finland. The experimental layout consists of three parallel treatment units: two different SAPS cells and one limestone-filled cell for comparison of performance. The SAPS cells are composed of a bottom layer of limestone and a top layer of compost supplemented with sand. One of the SAPS cells contains sulphate-rich, waste gypsum mixed with the compost layer in order to enhance the metal reduction by sulphate reducing-ba…
Tożsamość śląska. Rzeczywistość czy XX-wieczna kreacja?
2016
Tożsamość śląska jest przedmiotem szeroko zakrojonych badań politologów, socjologów i historyków. W większości skupiają się oni na poszukiwaniu jej genezy. W niniejszym artykule autor zamierza spojrzeć na tożsamość jako na zjawisko podlegające głębokiej ewolucji na przestrzeni lat. Odnosząc się do przytoczonej hipotezy „Śląska wymyślonego” spróbuje dokonać próby klarownego podziału pomiędzy tym co stanowi historyczny trzon tożsamości śląskiej, a tym co w XX wieku zostało wpisane w śląski kod kulturowy.
Campagnes, migrations internationales et nouvel ordre social ethnicisé. La zone viticole Utiel-Requena (Espagne)
2021
Utiel-Requena est une zone viticole traditionnelle de la province de Valence (Espagne), qui a connu une importante restructuration productive, l’arrivée de travailleurs immigrants et leur enracinement familial. Cet article aborde cette installation et les changements qu’elle a générés dans ces municipalités. Notre analyse des différentes sphères de la vie locale, telles que le travail, les espaces et services publics, la coexistence et les représentations symboliques, montre la constitution d’un ordre social ethnicisé qui consolide la position subalterne des immigrants et de leurs descendants. Utiel-Requena is a traditional wine-growing area in the province of Valencia (Spain), which has un…
Efectos conductuales y neuroquímicos del consumo de éxtasis y cocaína en ratones adolescentes.
2009
La 3,4-metilendioximetanfetamina (MDMA), una sustancia popularmente conocida como éxtasis, es una droga ilícita consumida habitualmente por adolescentes y adultos jóvenes. Además, el policonsumo es una práctica habitual entre los usuarios de la MDMA, siendo la cocaína una de las drogas más frecuentemente asociadas a esta sustancia. El objetivo del presente trabajo fue evaluar los efectos a corto y largo plazo que se producen tras la administración de la MDMA (5, 10, o 20 mg/kg) sola o en combinación con cocaína (25 mg/kg) en ratones adolescentes. En el estudio sobre el efecto agudo, observamos que ambas drogas administradas individual o simultáneamente incrementan la actividad motora. La do…
Neurochemical substrates of the rewarding effects of MDMA: implications for the development of pharmacotherapies to MDMA dependence.
2015
In recent years, studies with animal models of reward, such as the intracranial self-stimulation, self-administration, and conditioned place preference paradigms, have increased our knowledge on the neurochemical substrates of the rewarding effects of 3,4-methylenedioxymetamphetamine (MDMA) in rodents. However, pharmacological and neuroimaging studies with human participants are scarce. Serotonin [5-hydroxytryptamine (5-HT)], dopamine (DA), endocannabinoids, and endogenous opiates are the main neurotransmitter systems involved in the rewarding effects of MDMA in rodents, but other neurotransmitters such as glutamate, acetylcholine, adenosine, and neurotensin are also involved. The most impo…
ES Pamattiesību Hartas izmantošana Eiropas Savienības Tiesas judikatūrā un Hartas piemērojamības robežas
2015
Šī pētījuma mērķi ir noskaidrot Pamattiesību Hartas pielietojumu EST judikatūrā un noteikt Hartas piemērojamības robežas. Harta ir ES pamattiesību aizsardzības instruments, kurš galvenokārt attiecas uz Savienības iestādēm un struktūrām. Tomēr, piepildoties zināmiem priekšnosacījumiem, Harta var garantēt vis efektīvāko indivīda aizsardzības mehānismu arī dalībvalstu līmenī. Galvenais apstāklis, kas dalībvalstu līmenī liedz piemērot Hartu visās situācijās ir Hartas 51.pantā noteiktās piemērojamības robežas. Pētījuma rezultātā būs iespējams noteikt, kuras pamattiesības ir visbiežāk aizskartas ES līmenī un, kas ir šo pamattiesību šķietamais aizskārējs – Savienības institūcijas vai dalībvalsts. …
Effects of apomorphine on orienting reaction in the rat
2009
Aim of the research was to study the possible relationship between rapid apomorphine-induced modifications of midbrain dopaminergic neuron activity and rapid modifications of a motor response triggered by sensory stimuli (sensory-motor integration. Following apomorphine administration, ANOVA test revealed significant decrease of head turning latency and duration. A change on dopamine release, leading to an inhibition or facilitation of dopamine-mediated responses to environmental stimuli, may be hypothesized.
BMC Public Health
2022
Background In the past decades, climate change has been impacting human lives and health via extreme weather and climate events and alterations in labour capacity, food security, and the prevalence and geographical distribution of infectious diseases across the globe. Climate change and health indicators (CCHIs) are workable tools designed to capture the complex set of interdependent interactions through which climate change is affecting human health. Since 2015, a novel sub-set of CCHIs, focusing on climate change impacts, exposures, and vulnerability indicators (CCIEVIs) has been developed, refined, and integrated by Working Group 1 of the “Lancet Countdown: Tracking Progress on Health an…