Search results for "PAPER"
showing 10 items of 2166 documents
Domestic violence and public participation in the media
2013
Recent research suggests that as a social public problem, domestic violence is sustained in a number of social contexts that naturalize violence against women through gendered discourses and ideologies of male violence. This paper examines domestic violence vis-à-vis public participation in the media. In doing so, it seeks to explore the social public aspects of domestic violence and to investigate whether the gendered discourse of male violence is also sustained through the new electronic spaces of public participation. To this end, a corpus of unsolicited digital comments – a form of ‘citizen journalism’ – to a British online newspaper was compiled and analysed. This paper draws from rese…
Coercive metaphors in news headlines :a cognitive-pragmatic approach
2014
This article explores the application of metaphors in news headlines with a view to interrogating their potential for coercion. Coercion in news discourse is understood as a strategic deployment of pragma-linguistic devices, including metaphors, to foreground the representations of socio-political reality that are compatible with the interests of the news outlet rather than those that inform public debate. It is argued that coercion can be exposed through systematic discourse analysis. Methodologically, the study aims to integrate the cognitive and pragmatic approaches to metaphor in regarding it as both a conceptual building block of news representations and a strategic framing device in n…
Retórica periodística y controversias biopolíticas: El caso de las noticias sobre la polémica de las ‘hamburguesas gigantes’ (Esp…
2011
espanolEl objetivo de este articulo es analizar las estrategias retoricas de ‘nominacion’ o ‘referencia’ y de ‘predicacion’ (Reisigl & Wodak, 2001) como marcas linguisticas de la ‘actitud’ del redactor (Billig, 1991, 1996), utilizadas para describir a los dos principales actores sociales en una muestra de 29 noticias, publicadas en periodicos espanoles, sobre la polemica biopolitica de las ‘hamburguesas gigantes’ en 2006, que enfrento al Ministerio de Sanidad y Consumo espanol y a la empresa Burger King sobre la licitud de intervencion estatal en la regulacion de los habitos alimentarios. Se analizan las formas de nominacion empleadas para nombrar a los agentes enfrentados. La estrategia pr…
Mediatization of Politics: Theory and Data
2002
This article reports causes and consequences of the mediatization of politics about activities of the German parliament (Der Bundestag) and coverage of German politics in three national newspapers during 1951–1995. During this period, the number of decision-making activities remained fairly constant, the number of information activities significantly increased, and coverage of German politics changed: Although the number of reports triggered by events and issues remained fairly constant, the number of stories triggered by statements (about events or issues) significantly increased and those triggered by statements made by politicians increasingly overshadowed articles triggered by nonpoliti…
The malleability behind terms referring to common professional roles: the current meaning of “boss” in British newspapers
2018
L'objectiu de la present recerca és abordar la variació i ductilitat de conceptes aparentment clars i inequívocs relacionats amb els rols professionals habituals. L'estudi se centra en les estructures semàntiques, i subsegüents models cognitius, associats amb el terme 'boss', tal com són expressats i transmesos en l'actualitat a través dels grans mitjans de comunicació britànics. L'anàlisi lingüística, qualitatiu i quantitatiu, d'un corpus significatiu de textos en els quals apareix aquest terme mostra clares diferències en el seu significat, depenent de factors clau com l'orientació sociopolítica i ideològica de la plataforma de publicació.
Análisis contrastivo de la (des)cortesía en los comentarios digitales del periódico 20minutos.es y del Facebook de viajacontumascota.com: anonimato y…
2019
Esta investigación analiza las diferencias entre dos tipos de discursos digitales: las intervenciones reactivas a cinco posts por parte de los seguidores de una página de Facebook, ViajaconTuMascota.com, en la que existe cierta camaradería por la afición compartida; y los comentarios de lectores anónimos, entre los que no se establece esa solidaridad, a cinco noticias del periódico digital, 20minutos.es. Se pretende comprobar cómo inciden estas diferencias, la presencia o ausencia de solidaridad y el anonimato frente a la identidad real, cuando se producen desacuerdos: si se mantiene la cortesía social, a través de una cortesía mitigadora, o si se quiebra al activarse una estrategia de cibe…
Association between the rs6950982 polymorphism near the SERPINE1 gene and blood pressure and lipid parameters in a high-cardiovascular-risk populatio…
2012
The SERPINE1 (serpin peptidase inhibitor, clade E, member 1) gene, better known by its previous symbol PAI-1 (plasminogen activator inhibitor 1), has been associated with cardiovascular phenotypes with differing results. Our aim was to examine the association between the rs6950982 (G A) near the SERPINE1 gene, blood pressure (BP) and plasma lipid concentrations as well as the modulation of the polymorphism effects by adherence to Mediterranean diet (AMD). We studied 945 high-cardiovascular-risk subjects. Biochemical, clinical, dietary and genetic data (rs6950982) were obtained. We also determined the common rs1799768 (4G/5G), for checking independent effects. AMD was measured by a validate…
Pro-oxidant activity of indicaxanthin from Opuntia ficus indica modulates arachidonate metabolism and prostaglandin synthesis through lipid peroxide …
2014
Macrophages come across active prostaglandin (PG) metabolism during inflammation, shunting early production of pro-inflammatory towards anti-inflammatory mediators terminating the process. This work for the first time provides evidence that a phytochemical may modulate the arachidonate (AA) metabolism in lipopolysaccharide (LPS)-stimulated RAW 264.7 macrophages, promoting the ultimate formation of anti-inflammatory cyclopentenone 15deoxy-PGJ2. Added 1 h before LPS, indicaxanthin from Opuntia Ficus Indica prevented activation of nuclear factor-κB (NF-κB) and over-expression of PGE2 synthase-1 (mPGES-1), but up-regulated cyclo-oxygenase-2 (COX-2) and PGD2 synthase (H-PGDS), with final product…
Bcl-2 is a negative regulator of interleukin-1β secretion in murine macrophages in pharmacological-induced apoptosis
2010
BACKGROUND AND PURPOSE Cucurbitacin R, a natural anti-inflammatory product, has been shown to exhibit activity against both adjuvant-induced arthritis and delayed-type hypersensitivity reactions induced by various agents. Previous studies have demonstrated that the effects of cucurbitacin R stem from its inhibition of both cytokine production and lymphocyte proliferation. EXPERIMENTAL APPROACHES Effects of cucurbitacin R were investigated on lipopolysaccharide-stimulated RAW 264.7 cells. Cell cycle evolution was analysed by flow cytometry, detection of apoptosis by DNA ladder, Bcl-2, p21, p53, Bax, cleaved caspase-1 (p10), caspase-9, and caspase-3, cleaved caspase (p17) and interleukin-1β d…
Quaking and miR-155 interactions in inflammation and leukemogenesis.
2015
Quaking (QKI) is a tumor-suppressor gene encoding a conserved RNA-binding protein, whose expression is downregulated in several solid tumors. Here we report that QKI plays an important role in the immune response and suppression of leukemogenesis. We show that the expression of Qki is reduced in lipopolysaccharide (LPS)-challenged macrophages, suggesting that Qki is a key regulator of LPS signaling pathway. Furthermore, LPS-induced downregulation of Qki expression is miR-155-dependent. Qki overexpression impairs LPS-induced phosphorylation of JNK and particularly p38 MAPKs, in addition to increasing the production of anti-inflammatory cytokine IL-10. In contrast, Qki ablation decreases Fas …