Search results for "PARTICLES"
showing 10 items of 8085 documents
Hydroxypropylmethylcellulose films for the ophthalmic delivery of diclofenac sodium
2012
Abstract Objectives The aim of this study was to prepare diclofenac/hydroxypropylmethylcellulose (HPMC) and diclofenac-loaded nanoparticles/HPMC films as potential systems for ocular delivery. Methods Two different concentration of the polymer were used: 1.5 and 2.0% w/v. Chitosan–hyaluronic acid nanoparticles were prepared by the ionotropic gelation technique. Nanoparticles were characterized by transmission electron microscopy, dynamic light scattering, drug encapsulation efficiency and rheological studies. In-vitro drug studies and corneal penetration release studies were carried out. Drug release mechanism was finally evaluated by fitting the Ritger and Peppas equation to data. In addit…
Inhibition of skin inflammation in mice by diclofenac in vesicular carriers: Liposomes, ethosomes and PEVs
2013
Diclofenac-loaded phospholipid vesicles, namely conventional liposomes, ethosomes and PEVs (penetration enhancer-containing vesicles) were developed and their efficacy in TPA (phorbol ester) induced skin inflammation was examined. Vesicles were made from a cheap and unpurified mixture of phospholipids and diclofenac sodium; Transcutol P and propylene glycol were added to obtain PEVs, and ethanol to produce ethosomes. The structure and lamellar organization of the vesicle bilayer were investigated by transmission electron microscopy and small and wide angle X-ray scattering, as well as the main physico-chemical features. The formulations, along with a diclofenac solution and commercial Volta…
Fabrication of silver nanoparticles by a diethylene triamine-hyaluronic acid derivative and use as antibacterial coating
2022
In this work a synthetic protocol for the functionalization of hyaluronic acid with diethylenetriamine (DETA) was standardized. HA-DETA derivatives were characterized by NMR and proton carbon correlation analysis HSQC and HMBC to confirm chemical structure. A selected derivative was used to set up a green fabrication procedure for HA-DETA capped silver nanoparticles with the aim to achieve a polymeric based coating with potential application in the treatment of medical devices associated infections. Data from UV-visible spectroscopy, electron scanning and transmission microscope (STEM), photoelectric spectroscopy (XPS) and rheological characterization were combined to characterize the HA-DE…
Measurement of the inelastic proton-proton cross-section at √s = 7 TeV with the ATLAS detector
2011
The dependence of the rate of proton–proton interactions on the centre-of-mass collision energy, √s, is of fundamental importance for both hadron collider physics and particle astrophysics. The dependence cannot yet be calculated from first principles; therefore, experimental measurements are needed. Here we present the first measurement of the inelastic proton–proton interaction cross-section at a centre-of-mass energy, √s, of 7 TeV using the ATLAS detector at the Large Hadron Collider. Events are selected by requiring hits on scintillation counters mounted in the forward region of the detector. An inelastic cross-section of 60.3±2.1 mb is measured for ξ>5×10[superscript −6], where ξ is ca…
Apoferritin-encapsulated Ni and Co superparamagnetic nanoparticles
2006
Ni and Co nanoparticles (average diameters 3 and 3.5 nm) have been prepared within the apoferritin cavity. The protein shell prevents bulk aggregation of the metal particles, rendering them water soluble. X-Ray diffraction, transmission electronic microscopy and magnetization measurements have been used for characterizing the nanoparticles. The magnetic study of both nanoparticles confirmed the expected superparamagnetic behavior.
New rotational levels in $^{186}$Re nucleus
2020
International audience; Excited levels of 186 Re have been studied using results of the single γ -ray spectra measurements following the thermal neutron capture reaction. Energies and intensities of more than 500 γ -transitions have been obtained with the high-resolution crystal diffraction spectrometer GAMS5 of ILL. Most of the obtained intense γ -transitions have been placed in the 186 Re level scheme. A number of new levels, as well as the depopulation for levels observed earlier in the 187 Re (p,d)186 Re reaction measurements have been proposed. Structure of 186 Re levels is interpreted in terms of two-quasiparticle plus rotor coupling model and compared with that of the neighbouring do…
Levels of 188Re nucleus populated in thermal neutron capture reaction
2016
Abstract Levels of 188 Re populated in thermal neutron capture reaction with enriched 187 Re targets have been studied. Single γ -ray spectrum of 188 Re, measured with the high-resolution crystal diffraction spectrometer GAMS5, as well as γγ -coincidence experiments performed with high efficiency Ge detectors, allowed to develop model-independent level scheme of the doubly-odd 188 Re nucleus up to ∼ 1.5 MeV excitation energy. Analysis of the established 188 Re level scheme in terms of the quasiparticle-plus-rotor model indicates coexistence of axially-deformed and triaxial structures in the energy range above 400 keV.
Small-x, Diffraction and Vector Mesons
2015
This talk discusses recent progress in some topics relevant for deep inelastic scattering at small x. We discuss first differences and similarities between conventional collinear factorization and the dipole picture of deep inelastic scattering. Many of the recent theoretical advances at small x are related to taking calculations in the nonlinear saturation regime to next-to-leading order accuracy in the QCD coupling. On the experimental side significant recent progress has been made in exclusive and diffractive processes, in particular in ultraperipheral nucleus-nucleus collisions.
Hard diffraction in photoproduction with Pythia 8
2019
We present a new framework for modeling hard diffractive events in photoproduction, implemented in the general purpose event generator Pythia 8. The model is an extension of the model for hard diffraction with dynamical gap survival in pp and ppbar collisions proposed in 2015, now also allowing for other beam types. It thus relies on several existing ideas: the Ingelman-Schlein approach, the framework for multiparton interactions and the recently developed framework for photoproduction in gamma p, gamma gamma, ep and $e^+e^-$ collisions. The model proposes an explanation for the observed factorization breaking in photoproduced diffractive dijet events at HERA, showing an overall good agreem…
Hard single diffraction in p̄p collisions at s=630 and 1800 GeV
2002
Using the D empty set detector, we have studied events produced in (p) over barp collisions that contain large forward regions with very little energy deposition ("rapidity gaps") and concurrent jet production at center-of-mass energies of roots = 630 and 1800 GeV. The fraction of events with forward or central jets associated with rapidity gaps is compared to predictions for hard diffraction. We also extract the momentum loss for scattered protons in such processes. (C) 2002 Elsevier Science B.V. All rights reserved.