Search results for "PASI"
showing 10 items of 162 documents
A multicenter, randomized, blinded, phase III study of pasireotide LAR versus octreotide LAR in patients with metastatic neuroendocrine tumors (NET) …
2013
4031 Background: The novel somatostatin analog (SSA) pasireotide has a broader binding profile than currently available SSA (octreotide and lanreotide). Results from a phase III study (NCT00690430) of pasireotide LAR (P) vs octreotide LAR (O) in patients (pts) with NET and disease-related symptoms uncontrolled by the maximum approved dose of available SSA are shown. Methods: Pts (N=110) were randomized and stratified by predominant symptom at baseline (diarrhea [D], flushing [F], or D+F) 1:1 to P (60 mg IM) or O (40 mg IM) q28d. Primary objective was symptom response at month (M) 6. Secondary objectives included tumor response and safety. Progression-free survival (PFS) was an exploratory …
Bomberos pirómanos (1)
2008
Endringskapasitet – en nøkkel for å lykkes med gevinstrealisering i spesialisthelsetjenesten? : En studie av hvordan mellomledere opplever at endring…
2018
Masteroppgave i helse- og sosialinformatikk HSI500 - Universitetet i Agder 2018 Background: If an organisation is to reap the potential benefits of new technology, it must modify its work processes. However, the specialist health service appears to be experiencing significant challenges because it is constantly under pressure to change and improve its efficiency. This can weaken its capacity for change and, at worst, lead to long-term reductions in productivity and efficiency. Purpose: The purpose of this study is to examine how middle managers in the specialist health service feel they can influence developments in change capacity. The aim is to contribute to an awareness of the importance…
Effects of pasireotide treatment on coagulative profile: a prospective study in patients with Cushing's disease.
2018
Introduction: Cushing’s disease (CD) is characterized by procoagulative profile. Treatment with cortisol-reducing medications might normalize the coagulation impairment potentially eliminating the risk of thromboembolic complications. Aim: The aim of this prospective study is to evaluate the effectiveness of 6–12 months of treatment with pasireotide (Signifor®, Novartis) 600 µg twice daily on coagulative factors in 21 patients (16 females, mean age 46 ± 12.2 years) with CD. Biochemical, hormonal (urinary free cortisol, UFC; late night salivary cortisol, LNSC; ACTH) and coagulative parameters as Protrombin time (PT), aPTT, factors VIII, IX and XI, antithrombin III, protein C, protein S, fibr…
Muere Vidal-Beneyto, un conspirador contra el franquismo
2010
Modificazioni di insulino-secrezione, insulino-sensibilità e funzione adiposa durante terapia con pasireotide in un gruppo di pazienti con malattia d…
2016
Background: La terapia con pasireotide (PAS) è efficace nel miglioramento del quadro clinico e biochimico dei soggetti con Malattia di Cushing (MC) da adenoma ipofisario ACTH-secernente, ma una della principali cause di interruzione della stessa è l’insorgenza di eventi avversi, tra i quali l’iperglicemia è il più frequente. Obiettivi: Valutare l’effetto della terapia con PAS su metabolismo glucidico, insulino-secrezione e sensibilità. Metodi: Abbiamo valutato in 8 pazienti con MC recidivata post-chirurgia durante un follow-up terapeutico di 12 mesi, oltre ai parametri clinici ed ormonali, l’insulino-secrezione tramite HOMAβ e area sotto la curva del C-peptide (AUC2hc-peptide) durante MMTT,…
Brukertilfredshet i et elektronisk pasientjournalsystem – hva påvirker brukertilfredsheten? : Hva påvirker ansatte på et sykehus i Sør–Norges brukert…
2019
Masteroppgave helse- og sosialinformatikk HSI500 - Universitetet i Agder 2019 InnledningEtter hvert som befolkningen i Norge blir eldre og sykere er det et behov for informasjon om den enkelte pasient i helsevesenet. I Norge per i dag er det ingen felles journalløsninger som dekker alle nivåer i helsevesenet. Dette fører til at de som trenger informasjon ikke alltid har den nødvendige tilgangen. Det brukes forskjellige systemer avhengig av helseforetak, sykehus, kommune og lignende. På et sykehus i Sør –Norge brukes den elektroniske pasientjournalen (EPJ) DIPS, hvor alle nyansatte får opplæring før de gis tilgang til å dokumentere i DIPS. Denne studien forsøker å belyse opplæringens betydni…
Inventando el crimen pasional: del lenguaje de gacetilla a la prensa de sucesos (España, 1892-1920)
2021
El terme «crim passional» va sorgir a la premsa espanyola el 1892. L’objectiu d’aquest treball és desvelar el perquè i entendre’n la relació amb la premsa sensacionalista i, en especial, amb la premsa especialitzada en successos. La nostra metodologia considera que la premsa és un motor cultural en la construcció de conceptes amb incidència social. Així, doncs, explorem la presència del terme «crim passional» en un bon nombre de diaris i setmanaris per observar com es va construir un marc mental de naturalesa emocional. Es revela la incidència del concepte en l’opinió pública i en el llenguatge jurídic, així com la seva rellevància en la justificació de la violència contra les dones.
Romanzo giallo e aporia della verità: Spasimo di Federico De Roberto
2010
Il saggio analizza la struttura del giallo e i suoi rovesciamenti in Spasimo di Federico De Roberto.
The Besov capacity in metric spaces
2016
We study a capacity theory based on a definition of Haj{\l} asz-Besov functions. We prove several properties of this capacity in the general setting of a metric space equipped with a doubling measure. The main results of the paper are lower bound and upper bound estimates for the capacity in terms of a modified Netrusov-Hausdorff content. Important tools are $\gamma$-medians, for which we also prove a new version of a Poincar\'e type inequality.