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showing 10 items of 5265 documents

Red Blood Cell Distribution Is a Significant Predictor of Severe Illness in Coronavirus Disease 2019

2020

<b><i>Introduction:</i></b> As red blood cell distribution width (RDW) significantly predicts clinical outcomes in patients with respiratory tract infections and in those with critical illnesses, we performed a critical analysis of the literature to explore the potential prognostic role of this laboratory parameter in coronavirus disease 2019 (COVID-19). <b><i>Methods:</i></b> An electronic search was conducted in Medline, Scopus and Web of Science, using the keywords “coronavirus disease 2019” OR “COVID-19” AND “red blood cell distribution width” OR “RDW” in all fields, up to the present time, with no language restriction. Studies reporting t…

medicine.medical_specialtyRespiratory tract infectionsCoronavirus disease 2019 (COVID-19)business.industryCOVID-19 Coronavirus Red blood cell distribution widthMEDLINECOVID-19Red blood cell distribution widthHematologyGeneral Medicinemedicine.disease_causeCoronavirusRed blood cellmedicine.anatomical_structureRed blood cell distribution widthInternal medicinemedicineDistribution (pharmacology)In patientSystematic ReviewbusinessCoronavirus
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Analysis of cardiac and pulmonary complication probabilities after radiation therapy for patients with early-stage breast cancer

2009

Objective. The purpose of this study was to evaluate the radiobiological implications of clinical use of respiratory-gated techniques for postoperative radiation therapy of early-stage left-sided breast cancer after breast-conserving surgery. Material and methods. Radiation therapy treatment plans of 80 patients with early-stage breast cancer (stage I–II), receiving whole breast irradiation after breast-conserving therapy, were analyzed. The control group consisting of 47 patients received standard radiation therapy, and the respiratory-gated group consisting of 33 patients received deep inspiration-gated radiation therapy. Normal tissue complication probabilities (NTCP) for cardiac mortali…

medicine.medical_specialtyRespiratory-Gated Imaging TechniquesHeart Diseasesearly-stage breast cancermedicine.medical_treatmentBreast NeoplasmsMastectomy SegmentalStatistics NonparametricCohort StudiesBreast cancerWhole Breast Irradiationnormal tissue complication probabilitymedicineHumansBreastStage (cooking)Radiation Injuriesrespiratory-gated radiotherapyPneumonitisNeoplasm StagingProbabilitybusiness.industryrespiratory-gated radiotherapy; early-stage breast cancer; breast-conserving therapy; normal tissue complication probabilityPatient SelectionRespirationPulmonary ComplicationRadiotherapy DosageGeneral Medicinemedicine.diseaseLatviaSurgeryRadiation therapyRadiation Pneumonitisbreast-conserving therapyFemaleRadiotherapy AdjuvantRadiotherapy ConformalComplicationbusinessTomography X-Ray ComputedMastectomyMedicina
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The European trauma course – trauma teaching goes European

2014

The World Health Organization (WHO) has identified trauma as the major health care challenge of our century, claiming more productive life years worldwide than any other disease [1]. In the European Union (EU), injury accounts for 15 % of all deaths before the age of 60 years and is the fourth most common cause of death, with more than 235,000 deaths each year from injuries, equating to 600 injury fatalities per day [2]. In children, adolescents and young adults, accident and injury rates are even higher, being the leading cause of death in these age groups. Mortality from trauma in the EU has fallen 20 % in the past 20 years, to a rate of 63.7 per 100,000 in 2010 [3]. This reduction is par…

medicine.medical_specialtyResuscitationSports medicinemedia_common.quotation_subjecteducationMEDLINETraumatologyEmergency NursingCritical Care and Intensive Care MedicineCourse (navigation)Injury preventionHealth caremedicineHumansmedia_common.cataloged_instanceOrthopedics and Sports MedicineEuropean unionmedia_commonCause of deathPatient Care TeamMedical educationTeamworkPatient care teambusiness.industryMajor traumaEmergency Respondersmedicine.diseaseEuropeAnesthesiology and Pain MedicineTraumatologyFamily medicineEmergency MedicineWounds and InjuriesEducation Medical ContinuingSurgeryCardiology and Cardiovascular MedicinebusinessResuscitation
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Safety and Efficacy of Ranibizumab in Macular Edema following Retinal Vein Occlusion.

2013

Macular edema is the leading cause of visual impairment in patients with retinal vein occlusion. Limited improvements may be obtained with laser photocoagulation or intravitreal triamcinolone. However, according to the data provided by randomized clinical trials, intravitreal injections of ranibizumab (Lucentis; Genentech, South San Francisco, CA) constitute a new effective and safe option for the management of these vision-threatening diseases. The aim of the present review is to summarize the clinical evidence of ranibizumab for macular edema due to retinal vein occlusions.

medicine.medical_specialtyRetinal Veingenetic structuresReviewlaw.inventionRandomized controlled triallcsh:OphthalmologylawOphthalmologyOcclusionMedicineIn patientranibizumabMacular edemaIntravitreal triamcinolonemacular edemabusiness.industrymedicine.diseaseVEGFeye diseasesantiangiogenic therapylcsh:RE1-994retinal vein occlusionRetinal vein occlusionsRanibizumabbusinessBiomedical engineeringmedicine.drugOphthalmology and eye diseases
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Principles of Rhythm Management in Patients with Atrial Fibrillation

2020

Abstract Atrial fibrillation is a multilateral arrhythmia, which causes the clinician to encounter difficulties in its therapeutic approach for each new patient. The purpose of this paper aims in particular at evaluating the management of atrial fibrillation, namely its cardioversion and rhythm control. The population study consisted of 50 patients diagnosed with atrial fibrillation, who underwent transesophageal echocardiographic investigation before cardioversion. All of these patients had transesophageal echocardiography. Certain echocardiographic parameters, such as the size of the left atrium, the presence of intracavitary thrombi, the left atrial appendage flow velocity, and the prese…

medicine.medical_specialtyRhythmbusiness.industryInternal medicinecardiovascular systemCardiologymedicineIn patientAtrial fibrillationcardiovascular diseasesGeneral Medicinemedicine.diseasebusinessActa Medica Transilvanica
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Consortium for the lifespan examination of ADHD registry (Clear): An update on methodology and recruitment

2011

IntroductionADHD is often unrecognised and untreated, particularly in Europe. There is a need for improved understanding of ADHD in adults and its impact on patients across the lifespan. Registries allow for multiple real-world comparisons based on assessment of patients that are typically excluded from clinical studies. Data describing the cost, burden and consequences of ADHD are essential to inform clinicians, regulatory agencies, payers and patients about the condition.ObjectivesTo address the gaps in our current understanding of the care and cost of treating adult patients with ADHD by documenting real-life experiences.MethodsA prospective, longitudinal, observational study of adults &…

medicine.medical_specialtyRisk behaviourAdult patientsbusiness.industrymedicine.diseaseSubstance abusePsychiatry and Mental healthDisease severityHealth caremedicineObservational studyYoung adultbusinessPsychiatryEuropean Psychiatry
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Response to ‘Detecting right ventricular dysfunction in patients diagnosed with low-risk pulmonary embolism: is routine computed tomographic pulmonar…

2019

medicine.medical_specialtyRivaroxabanmedicine.diagnostic_testmedicine.drug_mechanism_of_actionbusiness.industryFactor Xa Inhibitormedicine.diseaseRight ventricular dysfunctionPulmonary embolismComputed tomographicAngiographyPulmonary angiographyMedicineIn patientRadiologyCardiology and Cardiovascular Medicinebusinessmedicine.drugEuropean Heart Journal
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Stauffer’s Syndrome in Patient with Metastatic Prostate Cancer

2019

Cholestasis is a symptom that can be present in many conditions, such as bile duct obstruction by malignant mases, obstruction by gallstone, acute and chronic viral hepatitis, and autoimmune disorders, such as primary biliary and sclerosing cholangitis. Stauffer syndrome is a rare type of paraneoplastic syndrome that presents as cholestasis with absence of underlying disease. Classically Stauffer syndrome has been described in renal cell cancer patients. In literature cholestasis as manifestation of paraneoplastic syndrome has also been described in patients with prostate adenocarcinoma and pancreatic and bronchogenic carcinoma. Conclusions. Stauffer syndrome should be kept in mind in patie…

medicine.medical_specialtyS syndromebusiness.industryBile duct030232 urology & nephrologyCase ReportGeneral Medicinemedicine.diseaseStauffer syndromelcsh:Diseases of the genitourinary system. Urologylcsh:RC870-923GastroenterologyBronchogenic carcinoma03 medical and health sciencesProstate cancer0302 clinical medicinemedicine.anatomical_structureCholestasis030220 oncology & carcinogenesisInternal medicinemedicineIn patientbusinessViral hepatitisCase Reports in Urology
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G.P.232

2014

Spinal muscular atrophy (SMA) and Pompe disease (PD) are common neuromuscular disorders during childhood causing progressive weakness of proximal muscles with gait disturbances, loss of ambulation and breathing difficulties. Whereas SMA is the result of a neurogenic atrophy caused by mutations in the SMN1 gene, PD is a lysosomal glycogen storage disease (type II) due to mutations of the GAA gene responsible for the enzyme activity of acid alpha-1,4-glucosidase. PD is treatable by enzyme replacement therapy, but in SMA there is no established curable therapy. We report on a child with genetically proven SMA type III and PD caused by mutations in the SMN1 and GAA genes. A 3 years old girl pre…

medicine.medical_specialtySMN1BiologyFasciculation03 medical and health sciences0302 clinical medicine030225 pediatricsInternal medicinemedicineOutpatient clinicGlycogen storage diseaseGenetics (clinical)Muscle biopsymedicine.diagnostic_testEnzyme replacement therapyAnatomySpinal muscular atrophymedicine.diseaseSMA*3. Good healthEndocrinologyNeurologyPediatrics Perinatology and Child HealthNeurology (clinical)medicine.symptom030217 neurology & neurosurgeryNeuromuscular Disorders
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Efficacy and acceptance of the sacral neuromodulation in the treatment of female lower urinary tract dysfunctions.

2017

medicine.medical_specialtySacrum030232 urology & nephrologyUrologyMEDLINEElectric Stimulation Therapylower urinary tract dysfunctionsacral neuromodulationFemale lower urinary tract03 medical and health sciences0302 clinical medicineMedicineHumansElectric stimulation therapyProspective StudiesProspective cohort study030219 obstetrics & reproductive medicineUrinary bladderbusiness.industryUrinary retentionUrinary Bladder OveractiveObstetrics and GynecologyMiddle AgedPatient Acceptance of Health CareUrinary RetentionSacrummedicine.anatomical_structureTreatment OutcomeSacral nerve stimulationFemalemedicine.symptombusinessMinerva ginecologica
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