Search results for "PC"

Consensus guidelines for the detection of immunogenic cell death

2014

Apoptotic cells have long been considered as intrinsically tolerogenic or unable to elicit immune responses specific for dead cell-associated antigens. However, multiple stimuli can trigger a functionally peculiar type of apoptotic demise that does not go unnoticed by the adaptive arm of the immune system, which we named "immunogenic cell death" (ICD). ICD is preceded or accompanied by the emission of a series of immunostimulatory damage-associated molecular patterns (DAMPs) in a precise spatiotemporal configuration. Several anticancer agents that have been successfully employed in the clinic for decades, including various chemotherapeutics and radiotherapy, can elicit ICD. Moreover, defect…

Catálogo de algunas antigüedades reunidas y conservadas por los Excmos. Señores Marqueses de Casa-Loring en su Hacienda de la Concepción.

Percepciones sobre «lo oriental» en el arte valenciano: el caso de los Baños del Almirante

2017

Resumen: El presente artículo trata la percepción de «lo oriental», algo muy actual en los tiempos que vivimos, sobre todo tras los altercados del 11 de septiembre del 2001, donde se reabrió la caja de Pandora en la visión negativa gestada de la sociedad musulmana. Abordaremos para ello la imagen del hammam, elemento patrimonial de la geografía española, centrando la investigación en el caso de los Baños del Almirante de Valencia, etiquetados erróneamente durante tiempo por la historiografía como islámicos, siendo en realidad cristianos. Abstract: The present article deals with the perception of «the oriental», a relevant topic nowadays, especially after the events of 11 September 2001, whe…

Spanish Nurses’ Knowledge about Palliative Care. A National Online Survey

2021

(1) Background: Nurses can find people with advanced diseases or in their last days of life during their professional careers and in many different care settings. For this reason, they need to have at least a basic level of palliative care education since they are the professional cohort treating these patients in a very close way. This research aims to determine the level of knowledge in palliative care of Spanish nurses and establish any possible difference based on their experience and training in palliative care. (2) Methods: A cross-sectional design using survey methods (distributed an online questionnaire) aimed at Spanish registered nurses. A validated questionnaire (PCQN-SV) was use…

BMC Public Health

2022

Background In the past decades, climate change has been impacting human lives and health via extreme weather and climate events and alterations in labour capacity, food security, and the prevalence and geographical distribution of infectious diseases across the globe. Climate change and health indicators (CCHIs) are workable tools designed to capture the complex set of interdependent interactions through which climate change is affecting human health. Since 2015, a novel sub-set of CCHIs, focusing on climate change impacts, exposures, and vulnerability indicators (CCIEVIs) has been developed, refined, and integrated by Working Group 1 of the “Lancet Countdown: Tracking Progress on Health an…

Bayesian correlated models for assessing the prevalence of viruses in organic and non-organic agroecosystems

2017

Cultivation of horticultural species under organic management has increased in importance in recent years. However, the sustainability of this new production method needs to be supported by scientific research, especially in the field of virology. We studied the prevalence of three important virus diseases in agroecosystems with regard to its management system: organic versus non-organic, with and without greenhouse. Prevalence was assessed by means of a Bayesian correlated binary model which connects the risk of infection of each virus within the same plot and was defined in terms of a logit generalized linear mixed model (GLMM). Model robustness was checked through a sensitivity analysis …

Gene expression specificity of the mussel antifungal mytimycin (MytM)

2011

Abstract We previously reported the nucleotide sequences and diversity of mytimycin (MytM) from the Mediterranean mussel, Mytilus galloprovincialis. Using real-time PCR (q-PCR), we observed that the MytM gene was mainly expressed in circulating hemocytes and to a less extent in the mantle. In vivo challenge with bacteria or with the yeast, Candida albicans, did not increase the expression as measured by q-PCR in hemocytes. By contrast, injection of the filamentous fungus, Fusarium oxysporum, induced a sudden and strong increase of expression at 9h p.i. (stimulation index of 25.7 ± 2.1). Optimum stimulating dose was 104 spores of F. oxysporum per mussel. In the same samples, AMP mytilin and …

Feria III. Die XXIV Maij Anno ... M.DCXXII. In Generali Congregatione Sanctae Romanae & Vniuersalis Inquisitionis, habita in Palatio Apostolico in Mo…

1622

Tres grav. amb símbols papals a la part superior de la f.

Del Estatut o Ordinatio per lo ... Rey en Marti, à refrenar los contraris qui ab color del Offici de la Inquisicio vexauen los Auengelizants, è Pre…

1616

Es tracta d'un trasllat, de l'Estatut donat pel Rei Martí I l'Humà, datat el 7 d'Abril de 1616 Totes les p. orlades i a dues col.

What is the meaning of ‘talent’ in the world of work?

2013

The ongoing confusion about the meaning of ‘talent’ within the world of work is hindering the establishment of widely accepted talent management theories and practices. The aim of this paper is to contribute to the literature on talent management by offering an indepth review of the talent concept within the specific context of the world of work, and proposing a framework for its conceptualization. We group different theoretical approaches to talent into ‘object’ (i.e., talent as natural ability; talent as mastery; talent as commitment; talent as fit) versus ‘subject’ approaches (i.e., talent as all people; talent as some people) and identify dynamics existing within and between them, as we…