Search results for "PCa"
showing 10 items of 130 documents
Comparison of canonical variate analysis and principal component analysis on 422 descriptive sensory studies
2015
International audience; Although Principal Component Analysis (PCA) of product mean scores is most often used to generate a product map from sensory profiling data, it does not take into account variance of product mean scores due to individual variability. Canonical Variate Analysis (CVA) of the product effect in the two-way (product and subject) multivariate ANOVA model is the natural extension of the classical univariate approach consisting of ANOVAs of every attribute. CVA generates successive components maximizing the ANOVA F-criterion. Thus, CVA is theoretically more adapted than PCA to represent sensory data. However, CVA requires a matrix inversion which can result in computing inst…
Prognostic value of nuclear matrix protein expression in localized prostate cancer.
2012
The aim of the study was to correlate nuclear matrix (NM) protein expression profiles with the risk of PSA progression or death in early prostate cancer (PCa).High-resolution two-dimensional gel electrophoresis (2D-PAGE) was used to identify tumor-associated NM proteins in the PCa specimens obtained from 94 patients. The association between the expression of each protein and the probability of PSA progression or death was studied through univariate analysis. Unsupervised hierarchical clustering analysis was then used to generate patient clusters showing comparable outcomes by including the proteins that were predictive at univariate analysis. PSA-free and overall survival curves relative to…
Liquid Biopsy in Prostate Cancer
2017
Chemotherapy is no longer the only therapeutic option for the treatment of advanced prostate cancer. The understanding of the pathophysiological mechanisms and its dynamic changes has divided neoplastic progression into different moments. Indeed prostate cancer changes over time from a state where cell proliferation is hormone-dependent to a stage where cell growth is hormone-independent (castration resistant disease, mCRPC). This knowledge has allowed the development of new generation hormonal agents that, along with the advent of new chemotherapeutic agents, have changed the long-term prognosis of this disease. As a result, the progression of prostate disease is dynamic over time and its …
Caratterizzazione chimico-morfologica di accessioni spontanee di origano siciliano (Origanum heracleoticum L.) del territorio dei monti Nebrodi
2009
Il genere Origano è estremamente diffuso nel bacino del Mediterraneo, con diverse specie presenti nel territorio siciliano. Il comprensorio dei Monti Nebrodi (Sicilia N-E), esteso per circa 200.000 ettari, è una delle aree siciliane in cui è presente la massima biodiversità vegetale; l'area è caratterizzato prevalentemente dalla presenza di Origanum heracleoticum, reperibile in ambienti ecologicamente anche assai diversificati. Con l'obiettivo di acquisire informazioni utili ai fini della caratterizzazione delle accessioni di Origanum heracleoticum spontanee nel comprensorio nebroideo, a partire dal 2007 è stato avviato su di esse un lavoro di ricognizione e collezione sistematica. Campioni…
Assessing Non-Photosynthetic Cropland Biomass from Spaceborne Hyperspectral Imagery
2021
Non-photosynthetic vegetation (NPV) biomass has been identified as a priority variable for upcoming spaceborne imaging spectroscopy missions, calling for a quantitative estimation of lignocellulosic plant material as opposed to the sole indication of surface coverage. Therefore, we propose a hybrid model for the retrieval of non-photosynthetic cropland biomass. The workflow included coupling the leaf optical model PROSPECT-PRO with the canopy reflectance model 4SAIL, which allowed us to simulate NPV biomass from carbon-based constituents (CBC) and leaf area index (LAI). PROSAIL-PRO provided a training database for a Gaussian process regression (GPR) algorithm, simulating a wide range of non…
Arginīna fosfāta ietekme uz elementu saturu egļu un priežu skujās
2021
Arginīna fosfāta ietekme uz elementu saturu egļu un priežu skujās. Pastors G., zinātniskais vadītājs Mg. ķīm. Bērtiņš M. Bakalaura darbs, 51 lappuses, 13 tabulas, 39 attēli, 31 literatūras avoti, 7 pielikumi. Latviešu valodā. Darbā veikts elementu salīdzinājums priežu un egļu skujās starp paraugiem, kuri tika apstrādāti ar arginīna fosfātu saturošu minerālmēslojumu sešu mēnešu ilgā augšanas periodā. Paraugu analīzēm izmantota induktīvi saistītās masspektometrijas un rezultāti apstrādāti ar galveno komponentu analīzes metodi. Paraugu priekšapstrāde veikta, izmantojot slapjās mineralizācijas metodi ar skābju maisījumu.
Drivers affecting the adoption and effectiveness of social media investments: The Italian wine industry case
2019
Purpose The purpose of this paper is twofold: first, to identify distinct organisational models in a sample of firms operating in the wine industry; and second, to identify the main internal resources that characterise those firms most motivated towards the adoption of social media (SM) tools and those that perceive SM investment as more effective. Design/methodology/approach The empirical investigation was carried out by administering an online questionnaire to a sample of 82 Sicilian wineries. The principal component analysis was used to identify latent factors that drive managers to invest in SM technologies and to measure the impact perceived by managers. Subsequently, a cluster analys…
Ķīmisko elementu satura sadalījums kviešos, atkarībā no augsnes mēslojuma un kviešu attīstības stadijas
2022
ĶĪMISKO ELEMENTU SATURA SADALĪJUMS KVIEŠOS, ATKARĪBĀ NO AUGSNES MĒSLOJUMA UN KVIEŠU ATTĪSTĪBAS STADIJAS. Dežurovs M., zinātniskā vadītāja Dr.chem. Rudoviča V., konsultante Mg. chem., pētniece Buša L. Maģistra darbs 41 lappuses, 15 attēli, 10 tabulas, 47 literatūras avoti. Latviešu valodā. Pētnieciskā darbā ir veikta bioloģiski un konvencionāli audzētu kviešu ķīmisko elementu satura analīze dažādās kviešu attīstības stadijās. Darbs veikts sadarbībā ar AREI Stendes institūta kolēģiem, kviešus audzējot parauglaukumos. Veikta kviešu paraugu ievākšana, mineralizācija un ķīmisko elementu analīze, izmantojot ICP-MS analīzes metodi. Izvērtēts metālisko elementu sadalījums kviešu lapās, stublājos un…
Analyzing and organizing the sonic space of vocal imitations
2015
The sonic space that can be spanned with the voice is vast and complex and, therefore, it is difficult to organize and explore. In order to devise tools that facilitate sound design by vocal sketching we attempt at organizing a database of short excerpts of vocal imitations. By clustering the sound samples on a space whose dimensionality has been reduced to the two principal components, it is experimentally checked how meaningful the resulting clusters are for humans. Eventually, a representative of each cluster, chosen to be close to its centroid, may serve as a landmark in the exploration of the sound space, and vocal imitations may serve as proxies for synthetic sounds.
Microanalytical method for studying paintings by use of fluorescence spectroscopy combined with principal component analysis
2013
Abstract The study of several different naturally aged films of organic painting materials, is described. Materials studied include drying oils (walnut, poppy seed and linseed oil) resin-based paint varnishes (the triterpenoid dammar and the diterpenoids sandarac and turpentine) and protein-based binding media (egg yolk and casein). A not expensive methodology for a rapid identification of binding media and varnishes, that applies principal component analysis (PCA) to Excitation Emission (EE) fluorescence spectra, is proposed. PCA was performed on a data matrix where the rows represent studied materials and columns the variables; the variables include the fluorescence intensities associated…