Search results for "PD"
showing 10 items of 1971 documents
Mesure de la section efficace de l'électroproduction de photons à JLAB dans le but d'effectuer une Séparation Rosenbluth de la contribution DVCS
2014
The study of the inner structure of hadrons allows us to understand the nature of the interactions between partons, quarks and gluons, described by Quantum Chromodynamics. The elastic scattering reactions, which have been studied in order to measure the nucleon form factors, are included in this frame. The inelastic scattering reactions are also included in this frame, they allow us to obtain information about the nucleon structure thanks to the development of the parton distribution functions (PDFs). While through elastic scattering we can obtain information about the charge distribution of the nucleon, and hence, about the spatial distribution of the partons, through inelastic scattering …
Response spectrum analysis of frame structures: reliability-based comparison between complete quadratic combination and damping-adjusted combination
2019
In the framework of seismic design of structures, response spectrum analysis (RSA) is the most commonly used approach in practice. The most popular combination rule is the complete quadratic combination (CQC) which is also prescribed by the most of seismic design codes and is based on the assumptions that the seismic acceleration is a white noise process and the peak factor ratios associated to the total and modal responses are unitary. Recently, the damping adjusted combination (DAC) rule has been developed for base-isolated structures to overcome the aforementioned simplified assumptions. Although it has been proved that the simplifications about peak factors lead to noticeable errors in …
Cigarette smoke affects the onco-suppressor DAB2IP expression in bronchial epithelial cells of COPD patients
2019
AbstractCigarette smoke is a risk factor for COPD and lung cancer. In cancer, epigenetic modifications affect the expression of Enhancer of Zester Homolog 2 (EZH2), and silenced disabled homolog 2 interacting protein gene (DAB2IP) (onco-suppressor gene) by Histone H3 tri-methylation in lysine 27 (H3K27me3). In“ex vivo”studies, we assessed EZH2, H3K27me3 and DAB2IP immunoreactivity in bronchial epithelial cells from COPD patients (smokers, ex-smokers), Smoker and control subjects. In“in vitro” experiments we studied the effect of cigarette smoke extract (CSE) on EZH2/H3K27me3/DAB2IP expression, apoptosis, invasiveness, and vimentin expression in 16HBE, primary cells, and lung cancer cell lin…
Sauszemes transportlīdzekļu apdrošināšana Latvijā
2015
Sauszemes transportlīdzekļu apdrošināšanas bizness ir ļoti savdabīgs, jo automobiļu apdrošināšana Latvijā ir obligāta prasība, kas garantē, ka pieprasījums nemazinās, bet gan tieši otrādi- tas ik gadu pieaug. Noslēguma darba tēma ir „Sauszemes transportlīdzekļu apdrošināšana.” Šī bakalaura darba mērķis ir izprast šīs apdrošināšanas apakšnozares vājās un stiprās puses, un izsecināt, kādas perspektīvas attīstāmas apdrošināšanas nozarē. Izstrādājot šo noslēguma darbu autors secina, ka sauszemes transportlīdzekļu apdrošināšanas tirgū vairāk uzmanības būtu jāpiesaista tieši obligātajai civiltiesiskajai transportlīdzekļu apdrošināšanai, jeb OCTA, kas jau pēdējos 10 gadus, ar viena gada pārtraukum…
Sauszemes transportlīdzekļu brīvprātīgā apdrošināšana Latvijā (KASKO) Latvijā un tās analīze
2020
Bakalaura darba nosaukums ir „Sauszemes transportlīdzekļu brīvprātīgā apdrošināšana (KASKO) Latvijā un tās analīze”. Darba mērķis ir uz sauszemes transportlīdzekļu brīvprātīgās apdrošināšanas (KASKO) Latvijā izpētes pamata izstrādāt priekšlikumus AAS “Baltijas Apdrošināšanas Nams”, turpmāk BAN, darbības veicināšanai. Bakalaura darbs sastāv no trīs nodaļām un vienpadsmit apakšnodaļām. Bakalaura darbam ir 67 lapaspuses. Pirmā nodaļa sastāv no teorētiskām zināšanām par apdrošināšanas tirgus būtību, definīciju apskatu, KASKO apdrošināšanas produkta, turpmāk KASKO, būtību. Darba autors konstatēja, ka par KASKO būtību un definīciju teorētiskajā literatūrā nav pieejams plašs informācijas klāsts. O…
An extended Darboux transformation to get families of solutions to the KPI equation
2023
By means of a Darboux transform with particular generating function solutions to the Kadomtsev-Petviashvili equation (KPI) are constructed. We give a method that provides different types of solutions in terms of particular determinants of order N. For any order, these solutions depend of the degree of summation and the degree of derivation of the generating functions. We study the patterns of their modulus in the plane (x, y) and their evolution according time and parameters.
Activation of metabotropic glutamate receptors induces propagating network oscillations in the intact cerebral cortex of the newborn mouse.
2006
Activation of metabotropic glutamate receptors (mGluRs) with (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid (ACPD) elicited in the frontal or occipital pole of the intact cerebral cortex preparation of the newborn mouse (P0-P3) a transient oscillatory field potential activity in the frequency range of 11-14Hz. These oscillations propagated over the whole cortical hemisphere and were blocked by tetrodotoxin, indicating that action potentials are required for the generation of this activity. Blockade of GABA-A receptors with gabazine did not influence the ACPD-induced network activity, but the glycine antagonist strychnine caused a significant decrease in the frequency, amplitude and durat…
Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin
2020
Human skin pigmentation results from the enzymatically controlled synthesis of melanin pigments in specialized organelles (melano‐somes) produced within epidermal melanocytes, followed by their transfer to neighboring keratinocytes and their distribution through‐out the epidermis.1 Constitutive skin pigmentation seems to be mostly genetically determined,2 being altered by numerous intrinsic and extrinsic factors affecting the epidermal melanin unit
Heat-stable antigen is expressed by murine keratinocytes and delivers costimulatory signals in T-cell activation.
1995
Heat-stable antigen (HSA), expressed by various antigen-presenting cells (APC), has been described as a costimulatory molecule for CD4+ T cells. Recently, we observed that HSA also serves as an important costimulatory molecule on epidermal Langerhans cells (LC). During these studies, low levels of HSA staining were also detected on normal murine keratinocytes (KC). To investigate whether HSA also is involved in T-cell activation by KC, normal murine KC or the spontaneously transformed KC cell-line PAM 212 were treated with PDB or PMA to induce HSA-expression. FACS analyses showed induction of HSA expression on normal murine KC, as well as PAM 212 cells. In functional assays PDB or PMA-treat…
Koherentās apdzīvotības oscilācijas atomos bez supersīkstruktūras
2015
Darbā tiek pētīta atomāra ansambļa uzvedība, ja tas atrodas divu lāzeru ar mazliet atšķirīgām frekvencēm laukā. Šādā situācijā tiek ierosinātas koherentās apdzīvotības oscilācijas - ansamblī notiek periodiskas, nerimstošas svārstības, kuru periods sakrīt ar lāzeru frekvenču starpībai atbilstošo periodu. Apskatot divu līmeņu sistēmu, skaitliski tiek iegūta ansambļa apdzīvotību un koherences atkarība no laika un tad, izmantojot Bloha sfēru, tiek analizēta šo atrisinājumu atkarība no abu lāzeru amplitūdu attiecības un abu lāzeru frekvenču nobīdes no atomārās pārejas rezonanses frekvences. J1=0→J2=1 pārejas gadījumā skaitliski tiek iegūta fluorescences signālu ar 3 ortogonālām polarizācijām atk…