Search results for "PEM"
showing 10 items of 623 documents
Le bébé gastronome
2018
L’alimentation des très jeunes enfants suscite de nombreuses interrogations : pourquoi Lou dévore-t-elle son plat d’épinards alors que Diego refusera catégoriquement d’y goûter ? Comment se fait-il qu’hier encore, Lou raffolait du gratin de courgettes alors qu’elle fait aujourd’hui la grimace dès qu’elle sent son odeur ? Et que faire avec Diego, qui dit « non » à tous les nouveaux plats qu’on lui propose ?Faut-il forcer un enfant à finir son assiette ? Comment peut-on proposer l’alimentation variée et équilibrée recommandée par les nutritionnistes quand un enfant refuse de goûter ?Il faut l’avouer, nourrir nos chers petits peut parfois s’avérer être un vrai casse-tête !
Alimentation des petits : plaisir ou casse-tête ?
2021
Toward Sustainable PLA-Based Multilayer Complexes with Improved Barrier Properties
2019
Poly(lactic acid) or PLA is currently considered as one of the most promising substitutes of conventional plastics, with low environmental impact, especially for food packaging applications. Nevertheless, some drawbacks, such as high permeability to oxygen, are still limiting its industrial applications. The objective of this study was to highly increase the oxygen barrier performance of PLA without compromising its sustainable nature and following the principles of circular economy perspective. Coproducts coming from mill industries, such as wheat gluten proteins (WG), were used to produce PLA-WG-PLA multilayer complexes with improved barrier performance. Different technologies of industri…
Equipements ludiques et sportifs de proximité et responsabilité des collectivités territoriales
2009
National audience
Catalyse : Systèmes d'intelligence territoriale pour le développement local
2000
Le centre MTI@SHS a conçu et expérimenté une méthode originale d'évaluation participative des actions locales de lutte contre la pauvreté et d'insertion socio-économique dans le cadre du programme “Pauvreté 3” de 1989 à 1993, sur le département du Doubs (France). Depuis 1994, de nombreux transferts ont été réalisés dans des contextes différents en Europe, concernant des thématiques d'action diversifiées, qui ont permis d’inscrire l’évaluation participative dans une logique d’observation et d’élaborer les outils nécessaires au transfert de la méthode, en particulier ceux qui sont orientés vers les acteurs locaux et qui facilitent à la fois le suivi individualisé et une relation partenariale …
Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription fa…
2017
Background: Ectomycorrhizal (ECM) fungi develop a mutualistic symbiotic interaction with the roots of their host plants. During this process, they undergo a series of developmental transitions from the running hyphae in the rhizosphere to the coenocytic hyphae forming finger-like structures within the root apoplastic space. These transitions, which involve profound, symbiosis-associated metabolic changes, also entail a substantial transcriptome reprogramming with coordinated waves of differentially expressed genes. To date, little is known about the key transcriptional regulators driving these changes, and the aim of the present study was to delineate and functionally characterize the trans…
Role of hypoxia in pemetrexed-resistance of mesothelioma mediated by proton-coupled folate transporter, and preclinical activity of new anti-LDH comp…
2018
Introduction There are few effective therapies for malignant pleural mesothelioma (MPM), which remains one of the most lethal cancers. We previously demonstrated that low expression of the PCFT transporter, both at mRNA and protein levels, is associated with shorter survival of MPM patients treated with pemetrexed (Giovannetti et al., 2017). Since hypoxia has also been associated to antifolate-resistance (Raz et al, 2014), this study was aimed at elucidating key factors in pemetrexed resistance and hypoxia that may contribute to the rational development of novel therapeutic interventions against mesothelioma. Methods The levels of PCFT and of the hypoxia marker carbonic anhydrase-IX were de…
The territorial dimension in the EU programming and the New Framework for Public Policies: Territorial Tural Development, CAP Reform and new LEADER
2012
Lo que venimos denominando como perspectiva territorial del desarrollo es un fenómeno bastante reciente en el contexto de la Unión Europea, de apenas dos décadas. En esencia esta perspectiva territorial del desarrollo se ha centrado en un enfoque local de los procesos de desarrollo en las áreas rurales, de la mano, principalmente, de instrumentos como LEADER. La necesidad de incorporar la dimensión territorial a los procesos de desarrollo proviene no solo del éxito global de estos instrumentos, sino también por el convencimiento de que puede constituir un elemento fundamental de cara a la cohesión económica y social en el seno de la UE. Avances recientes, como el Libro Verde de la Cohesión …
Entre Etat et marché : une nouvelle régulation sanitaire pour les pays en développement
2004
Stéphane Tizio — Between State and market : A new sanitary regulation for developing countries ? This paper is positioned in a critical perspective of the most recent international recommendations in matters of health in developing countries and particularly in Sub- Saharan African countries. A brief history of health policies shows that the promotion of these new instruments is greatly owed to the limits of the State and market models of organising health systems. Proceeding from the neo-institutional models of such new health policies, we shall demonstrate the implications and limits consisting, among other things, of discarding the political and ethical dimensions of regulating health sy…
Le réseau de développement professionnel des managers. Quels déterminants?
2010
Explaining the professionnal development network of managers In spite of the interest for social networks, the determinants of these have not been explored. In this article we wonder what is the role of people in the building of their personal developmental network. A quantitative study test how behavior, personality and job design variables impact the pattern of network.