Search results for "PEOPLE"
showing 10 items of 1330 documents
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness…
2011
Carotid intima media thickness (cIMT) and plaque determined by ultrasonography are established measures of subclinical atherosclerosis that each predicts future cardiovascular disease events. We conducted a meta-analysis of genome-wide association data in 31,211 participants of European ancestry from nine large studies in the setting of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. We then sought additional evidence to support our findings among 11,273 individuals using data from seven additional studies. In the combined meta-analysis, we identified three genomic regions associated with common carotid intima media thickness and two different regions a…
Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.
2017
The Strategic Implementation Plan of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) proposed six Action Groups. After almost three years of activity, many achievements have been obtained through commitments or collaborative work of the Action Groups. However, they have often worked in silos and, consequently, synergies between Action Groups have been proposed to strengthen the triple win of the EIP on AHA. The paper presents the methodology and current status of the Task Force on EIP on AHA synergies. Synergies are in line with the Action Groups' new Renovated Action Plan (2016-2018) to ensure that their future objectives are coherent and fully connected. The …
Cortisol and the aging brain: Hypothalamic-pituitary-adrenal axis and cognitive performance in older people.
2015
One of the greatest achievements in modern society is the increase in life expectancy. This increment is so great that children born after 2011 have a one in three chance of reaching their 100th birthday, and specifically in Europe, a quarter of the population will be over 60 years of age by 2020 (European Commission, 2014). This is an important change in society that is occurring for the first time in human history and producing new challenges that need to be addressed, especially those concerning age-related health problems. In this regard, one of the main aims of new research programs, such as Horizon 2020 in Europe, is to increase the possibilities of keeping older people healthy and in…
Contribution of the physical, social, psychological and environmental domains to overall quality of life of the elderly
2006
Este estudo investigou a contribuição de cada domínio da qualidade de vida (físico, social, psicológico e ambiental) na qualidade de vida global e em que extensão esses domínios explicam a qualidade de vida global de idosos residentes no município de Teixeiras, na Região Sudeste do Brasil. Trata-se de um estudo observacional de corte transversal, sendo a amostragem aleatória estratificada por sexo, uso do Programa Saúde da Família e microárea de saúde (n = 211, indivíduos com idade igual ou superior a 60 anos), representando 14,28% do total de idosos do município em estudo. O instrumento utilizado foi o Word Health Organization Quality of Life Instrument Bref (WHOQOL-Bref), proposto pela Or…
Résidents et personnel en établissement d'hébergement pour personnes agées dépendantes (EHPAD) : création ou recréation de liens spécifiques en milie…
2019
This thesis studies the specific relationship that develops between the staff, the residents and their family and friends in retirement homes for dependents elderly in a rural environment.The aim is to analyse the creation process by the actors to go from an acquaintanceship network to an interdependence network and how each adapts, reorganise, more or less, among facilities where the legislator codified strongly the relational framework.The arrival to a retirement home marks, in all cases, a strong biographical break. For a little of people, it means having to accept abandoning a significant part of their past life. It forces the residents to (re)build themselves a new identity, a new stat…
Phenomenological perspectives on self-care in aging.
2013
Olle SöderhamnCenter for Caring Research- Southern Norway, Faculty of Health and Sport Sciences, University of Agder, Grimstad, NorwayAbstract: Self-care is a central concept in health care and may be considered as a means to maintain, restore, and improve one's health and well-being. When performed effectively, self-care contributes not only to human functioning but also to human structural integrity and human development (ie, to a dynamic and holistic state of health). Self-care as a clinical concept is relevant for health care professionals, and it should be meaningful to investigate it at a philosophical level and to further elaborate upon this concept. The aim of this …
Caring for People With Dementia Under COVID-19 Restrictions: A Pilot Study on Family Caregivers
2021
IntroductionThe present pilot study examined to what extent the COVID-19 lockdown affected the behavioral and psychological symptoms of dementia (BPSD) in people with dementia and worsened their family caregivers’ distress. The associations between changes in the BPSD of relatives with dementia (RwD) and in their caregivers’ distress, and sense of social and emotional loneliness, and resilience were also investigated.Materials and MethodsThirty-five caregivers of RwD attending formal healthcare services before the COVID-19 lockdown volunteered for the study, and were interviewed by phone during the lockdown. Caregivers completed the NeuroPsychiatric Inventory (NPI) to assess their care reci…
Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology
2015
Primary open-angle glaucoma is the most common optic neuropathy and an important cause of irreversible blindness worldwide. The optic nerve head or optic disc is divided in two parts: a central cup (without nerve fibers) surrounded by the neuroretinal rim (containing axons of the retinal ganglion cells). The International Glaucoma Genetics Consortium conducted a meta-analysis of genome-wide association studies consisting of 17,248 individuals of European ancestry and 6,841 individuals of Asian ancestry. The outcomes of the genome-wide association studies were disc area and cup area. These specific measurements describe optic nerve morphology in another way than the vertical cup-disc ratio, …
Effect of Foreperiod Duration and Handedness on Simple and Choice Auditory Reaction Time Among the Older People
2017
Objectives Cognitive functions such as reaction time undergo change with aging. Given the importance of preparation in response to reaction time in various life situations, this study aimed to examine the effect of various foreperiods (0.5, 1.5, 2.5, and 3.5 s), and handedness at the time of simple and choice auditory reaction time. Methods & Materials The current research followed a quasi-experimental methodology and was carried out using a self-made software. The study population comprised all old people living in Ahvaz City. Of them, 30 people were selected through purposive sampling method and allocated into two groups of right- and left-handed people. Each individual was randomly teste…
Subjective Memory Complaints and Decision Making in Young and Older Adults: An Event-Related Potential Study
2021
Subjective memory complaints (SMCs) may affect decision-making processes. This study aimed to investigate the neuronal correlates of feedback processing during a decision-making task in young and older adults with and without SMCs. Event-related potentials and behavioral performance during the Iowa gambling task were recorded in a total of 136 participants (65 young adults, 71 older adults). The participants were divided into two groups according to their SMCs (with SMCs: n = 60, without SMCs: n = 76). Feedback-related negativity (FRN) and P3 were analyzed in the feedback stage of the decision-making process. Older adults with SMCs scored worse in the ambiguity phase than older adults witho…