Search results for "PEPTIDES"

showing 10 items of 2897 documents

Changes in lipid composition in tobacco cells treated with cryptogein , an elicitor from Phytophthora cryptogea

1995

Abstract Changes in lipid composition occurred when tobacco cells (Nicotiana tabacum var. Xanthi) were treated with cryptogein, a proteinaceous elicitor from Phytophthora cryptogea. The most striking change was an increase in acylated steryl glycosides and steryl esters levels, certainly resulting from the glycosylation and/or esterification of free sterols. Moreover, in vivo pulse-labelling experiments with [14C]acetate also showed that a progressive decline in the incorporation rate of [14C]acetate into free sterols started with the induction of sesquiterpenoid synthesis and lasted when sesquiterpenoid synthesis stops. This phenomenon was accompanied by a significant increase in the synth…

0106 biological sciencesGlycosylationNicotiana tabacumPlant Science01 natural sciences[SDV.GEN.GPL]Life Sciences [q-bio]/Genetics/Plants genetics03 medical and health scienceschemistry.chemical_compoundBiosynthesis[SDV.GEN.GPL] Life Sciences [q-bio]/Genetics/Plants geneticsGeneticsComputingMilieux_MISCELLANEOUS030304 developmental biologychemistry.chemical_classificationPhosphatidylethanolamine0303 health sciencesbiologyPhytophthora cryptogeaPhytoalexinGlycosideGeneral Medicinebiology.organism_classification3. Good healthElicitorchemistryBiochemistrylipids (amino acids peptides and proteins)Agronomy and Crop Science010606 plant biology & botany
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Type-2 histone deacetylases as new regulators of elicitor-induced cell death in plants

2011

 voir Addenda, notes additionnelles complétant l'article : "Dahan, J., Hammoudi, V., Wendehenne, D., Bourque, S. (2011). Type 2 histone deacetylases play a major role in the control of elicitor-induced cell death in tobacco. Plant signaling & behavior, 6 (11), 1865-1867. DOI : 10.4161/psb.6.11.17848".; International audience; Plant resistance to pathogen attack is often associated with a localized programmed cell death called hypersensitive response (HR). How this cell death is controlled remains largely unknown. Upon treatment with cryptogein, an elicitor of tobacco defence and cell death, we identified NtHD2a and NtHD2b, two redundant isoforms of type-2 nuclear histone deacetylases (HDACs…

0106 biological sciencesHypersensitive responseProgrammed cell deathPhysiologyplant defenceNicotiana tabacum[SDV]Life Sciences [q-bio]Molecular Sequence DataHistone Deacetylase 2Plant Science01 natural sciencesMass SpectrometrycryptogeinFungal Proteins03 medical and health sciences[ SDV.SA.AGRO ] Life Sciences [q-bio]/Agricultural sciences/AgronomyTobaccoAmino Acid SequencePhosphorylationNuclear proteinPhylogeny030304 developmental biology0303 health sciencesbiologyNicotiana tabacumAlgal ProteinsNuclear Proteinsfood and beveragesAcetylationbiology.organism_classificationElicitorCell biologyHistonecell deathhypersensitive response (HR)Acetylationhistone deacetylasebiology.proteinHistone deacetylasePeptidesSequence AlignmentChromatography Liquid010606 plant biology & botanynuclear signalling
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Plasma membrane sterol complexation, generated by filipin, triggers signaling responses in tobacco cells

2010

International audience; The effects of changes in plasma membrane (PM) sterol lateral organization and availability on the control of signaling pathways have been reported in various animal systems, but rarely assessed in plant cells. In the present study, the pentaene macrolide antibiotic filipin III, commonly used in animal systems as a sterol sequestrating agent, was applied to tobacco cells. We show that filipin can be used at a non-lethal concentration that still allows an homogeneous labeling of the plasma membrane and the formation of filipin-sterol complexes at the ultrastructural level. This filipin concentration triggers a rapid and transient NADPH oxidase-dependent production of …

0106 biological sciencesMembrane Fluidity[SDV]Life Sciences [q-bio]CellBiophysicsPLANTEBiology01 natural sciencesFilipinBiochemistry03 medical and health scienceschemistry.chemical_compoundTobaccomedicinepolycyclic compoundsMEMBRANE PLASMIQUEFilipinPhosphorylation030304 developmental biologySterolchemistry.chemical_classification0303 health sciencesReactive oxygen speciesCell DeathCell MembranePhytosterolsPlantCell BiologyPlant cellSterolCell biologymedicine.anatomical_structurechemistrySignalizationPotassiumSIGNALISATIONPhosphorylationlipids (amino acids peptides and proteins)sense organsSignal transductionReactive Oxygen SpeciesLaurdanSignal Transduction010606 plant biology & botanyPlasma membraneBiochimica et Biophysica Acta (BBA) - Biomembranes
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Phosphorylated intermediate of a transport ATPase and activity of protein kinase in membranes from corn roots

1983

A maize-root microsomal fraction was enriched in ATPase by treatment with Triton X-100. This activity, which reached 1.2-2.0/mumol Pi x min-1 x mg protein-1, was specific for ATP, very slightly stimulated by K+, inhibited by orthovanadate and diethylstilbestrol, resistant to oligomycin and azide, and had a Km of 1.2 mM MgATP. Incubation of the microsomal fraction with [gamma 32-P]ATP followed by electrophoresis in acid conditions revealed the presence of several phosphoproteins. The phosphorylation of a 110000-Mr polypeptide reached the steady-state level in less than 5 s and rapidly turned over the phosphate group. The phosphorylation level was an hyperbolic function of the [ATP] with a Km…

0106 biological sciencesOligomycinATPaseHydroxylamineHydroxylaminesZea mays01 natural sciencesBiochemistry03 medical and health scienceschemistry.chemical_compoundHydroxylamineCationsMicrosomes[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyVanadate[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyPhosphorylationProtein kinase ADiethylstilbestrol030304 developmental biologyAdenosine Triphosphatases2. Zero hunger0303 health sciencesbiologyCell MembraneBiological TransportVanadiumMolecular biologyMembranechemistryBiochemistryPhosphoproteinbiology.proteinPhosphorylationVanadatesPeptidesProtein Kinases010606 plant biology & botany
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Membrane glycerolipid remodeling triggered by nitrogen and phosphorus starvation in Phaeodactylum tricornutum.

2014

International audience; Diatoms constitute a major phylum of phytoplankton biodiversity in ocean water and freshwater ecosystems. They are known to respond to some chemical variations of the environment by the accumulation of triacylglycerol, but the relative changes occurring in membrane glycerolipids have not yet been studied. Our goal was first to define a reference for the glycerolipidome of the marine model diatom Phaeodactylum tricornutum, a necessary prerequisite to characterize and dissect the lipid metabolic routes that are orchestrated and regulated to build up each subcellular membrane compartment. By combining multiple analytical techniques, we determined the glycerolipid profil…

0106 biological sciencesPhysiologyPlant ScienceThylakoids01 natural sciencesPhaeodactylum tricornutumTranscriptomeMGDGNutrientnutrient starvationLipids metabolismSettore BIO/04 - Fisiologia VegetaleDigalactosyldiacylglycerolPhospholipids0303 health sciencesbiologyNitrogen starvationmicroalgaeMonogalactosyldiacyglycerolPhosphorusArticlesAdaptation PhysiologicalBiochemistryThylakoidSulfoquinovosyldiacylglycerollipids (amino acids peptides and proteins)DGDGNitrogenchemistry.chemical_elementlipidsMembrane Lipids03 medical and health sciencesSQDG[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyGenetics[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular Biology14. Life underwaterPhaeodactylum tricornutumTriglycerides030304 developmental biologyDiatomsMembranesGene Expression ProfilingPhosphorusfungiPhosphorus starvationGlycerolipidsLipid metabolismmetabolic pathwaybiology.organism_classificationMetabolic pathwayPhosphatidylcholineDiatomchemistryPhytoplanktonLipidomics010606 plant biology & botany
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Immune response affects ant trophallactic behaviour.

2008

5 pages; International audience; Sociality is associated with many benefits that have favoured its evolution in social insects. However, sociability also presents disadvantages like crowding of large numbers of individuals, which may favour the spread of infections within colonies. Adaptations allowing social insects to prevent and/or control pathogen infections range from behavioural responses to physiological ones including their immune systems. In a state of infection, social interactions with nestmates should be altered in a way which might prevent its spreading. We simulated a microbial infection in workers of the ant Camponotus fellah by the administration of peptidoglycan (PGN) and t…

0106 biological sciencesPhysiology[ SDV.BA.ZI ] Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyAdaptation BiologicalPeptidoglycanBiologySocial interactions010603 evolutionary biology01 natural sciencesAntibacterial peptidesLife history theory03 medical and health sciencesImmune system[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimals[ SDV.IMM ] Life Sciences [q-bio]/ImmunologyIsraelImmune responseSocial BehaviorFormicidaeSociality030304 developmental biology0303 health sciencesAnalysis of Variance[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyAntsFeeding BehaviorANTAntibacterial peptide[SDV.BA.ZI]Life Sciences [q-bio]/Animal biology/Invertebrate ZoologyInsect ScienceImmunology[SDV.IMM]Life Sciences [q-bio]/ImmunologyEncapsulation[SDE.BE]Environmental Sciences/Biodiversity and EcologyTrophallaxisTrophallaxisCamponotus fellah[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/Symbiosis
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Elicitins trap and transfer sterols from micelles, liposomes and plant plasma membranes

1999

Using elicitins, proteins secreted by some phytopathogenic Oomycetes (Phytophthora) known to be able to transfer sterols between phospholipid vesicles, the transfer of sterols between micelles, liposomes and biological membranes was studied. Firstly, a simple fluorometric method to screen the sterol-carrier capacity of proteins, avoiding the preparation of sterolcontaining phospholipidic vesicles, is proposed. The transfer of sterols between DHE micelles (donor) and stigmasterol or cholesterol micelles (acceptor) was directly measured, as the increase in DHE fluorescence signal. The results obtained with this rapid and easy method lead to the same conclusions as those previously reported, u…

0106 biological sciencesPhytophthoraTime FactorsStigmasterolBiophysics01 natural sciencesMicelleBiochemistryFluorescenceFungal Proteins03 medical and health scienceschemistry.chemical_compoundErgosterolpolycyclic compoundsMicellesPlant Proteins030304 developmental biology0303 health sciencesLiposomeStigmasterolChemistryVesicleAlgal ProteinsCell MembraneProteinsElicitinBiological membraneLipid–protein interactionCell BiologyPlantsElicitinSterolsCholesterolMembraneBiochemistryDehydroergosterolLiposomeslipids (amino acids peptides and proteins)CryptogeinCarrier ProteinsFluorescence anisotropy010606 plant biology & botanyBiochimica et Biophysica Acta (BBA) - Biomembranes
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An overview of natural antimicrobials role in food

2017

The present paper aims to review the natural food preservatives with antimicrobial properties emphasizing their importance for the future of food manufacturing and consumers' health. The extraction procedures applied to natural antimicrobials will be considered, followed by the description of some natural preservatives' antimicrobial mechanism of action, including (i) membrane rupture with ATP-ase activity inhibition, (ii) leakage of essential biomolecules from the cell, (iii) disruption of the proton motive force and (iiii) enzyme inactivation. Moreover, a provenance-based classification of natural antimicrobials is discussed by considering the sources of origin for the major natural prese…

0106 biological sciencesPreservativeFood industryAntimicrobial peptidesMicrobial Sensitivity Tests01 natural sciences0404 agricultural biotechnologyMicrobial resistanceAnti-Infective AgentsParasitic Sensitivity Tests010608 biotechnologyDrug DiscoveryAgrártudományokAnimalsHumansParasitesPharmacologyBiological ProductsBacteriaÉlelmiszertudományokChemistrybusiness.industryActivity inhibitionOrganic ChemistryFungi04 agricultural and veterinary sciencesGeneral MedicineAntimicrobialFood safetyBiopreservation040401 food scienceBiotechnologyFood PreservativesbusinessEuropean Journal of Medicinal Chemistry
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Quantitative proteomics reveals a dynamic association of proteins to detergent-resistant membranes upon elicitor signaling in tobacco.

2009

International audience; A large body of evidence from the past decade supports the existence, in membrane from animal and yeast cells, of functional microdomains playing important roles in protein sorting, signal transduction, or infection by pathogens. In plants, as previously observed for animal microdomains, detergent-resistant fractions, enriched in sphingolipids and sterols, were isolated from plasma membrane. A characterization of their proteic content revealed their enrichment in proteins involved in signaling and response to biotic and abiotic stress and cell trafficking suggesting that these domains were likely to be involved in such physiological processes. In the present study, w…

0106 biological sciencesProteomicsGTPase-activating proteinQuantitative proteomicsDetergentsPlasma protein bindingBiologymedicine.disease_causeProteomics01 natural sciencesBiochemistryMass SpectrometryAnalytical ChemistryCell membraneFungal Proteins03 medical and health sciencesProtein targetingTobaccomedicine[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMolecular Biology030304 developmental biologyPlant Proteins0303 health sciencesFungal proteinStaining and LabelingResearchAlgal ProteinsCell MembraneCell biologymedicine.anatomical_structureBiochemistryLuminescent MeasurementsSignal transductionPeptidesReactive Oxygen Species010606 plant biology & botanyProtein BindingSignal TransductionMolecularcellular proteomics : MCP
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Reducing the effect of beauvericin on neuroblastoma SH-SY5Y cell line by natural products

2020

Abstract In the present work, different natural compounds from coffee by-product extracts (coffee silverskin and spent coffee) rich in polyphenols, was investigated against beauvericin (BEA) induced-cytotoxicity on SH-SY5Y cells. Spent coffee arise as waste products through the production of instant coffee and coffee brewing; while the silverskin is a tegument which is removed and eliminated with toasting coffee grains. First of all, polyphenol extraction methods, measurement of total polyphenols content and its identification were carried out. Afterwards evaluating in vitro effects with MTT assay on SH-SY5Y cells of coffee by-product extracts and mycotoxins at different concentrations and …

0106 biological sciencesSH-SY5YToxicologyCoffee01 natural sciencesAntioxidantsNeuroblastoma03 medical and health scienceschemistry.chemical_compoundChlorogenic acidCell Line TumorDepsipeptidesHumansMTT assayFood scienceMycotoxinBiological Products0303 health sciencesPlant ExtractsChemistrybusiness.industry010604 marine biology & hydrobiology030302 biochemistry & molecular biologyfood and beveragesMycotoxinsBeauvericinCell culturePolyphenolBrewingbusinessToxicon
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