Search results for "PIDE"
showing 10 items of 6055 documents
Epidemic spreading and aging in temporal networks with memory
2018
Time-varying network topologies can deeply influence dynamical processes mediated by them. Memory effects in the pattern of interactions among individuals are also known to affect how diffusive and spreading phenomena take place. In this paper we analyze the combined effect of these two ingredients on epidemic dynamics on networks. We study the susceptible-infected-susceptible (SIS) and the susceptible-infected-removed (SIR) models on the recently introduced activity-driven networks with memory. By means of an activity-based mean-field approach we derive, in the long time limit, analytical predictions for the epidemic threshold as a function of the parameters describing the distribution of …
Nowcasting COVID‐19 incidence indicators during the Italian first outbreak
2020
A novel parametric regression model is proposed to fit incidence data typically collected during epidemics. The proposal is motivated by real-time monitoring and short-term forecasting of the main epidemiological indicators within the first outbreak of COVID-19 in Italy. Accurate short-term predictions, including the potential effect of exogenous or external variables are provided. This ensures to accurately predict important characteristics of the epidemic (e.g., peak time and height), allowing for a better allocation of health resources over time. Parameter estimation is carried out in a maximum likelihood framework. All computational details required to reproduce the approach and replica…
Centrality measures for networks with community structure
2016
Understanding the network structure, and finding out the influential nodes is a challenging issue in the large networks. Identifying the most influential nodes in the network can be useful in many applications like immunization of nodes in case of epidemic spreading, during intentional attacks on complex networks. A lot of research is done to devise centrality measures which could efficiently identify the most influential nodes in the network. There are two major approaches to the problem: On one hand, deterministic strategies that exploit knowledge about the overall network topology in order to find the influential nodes, while on the other end, random strategies are completely agnostic ab…
Immunization Strategies Based on the Overlapping Nodes in Networks with Community Structure
2016
International audience; Understanding how the network topology affects the spread of an epidemic is a main concern in order to develop efficient immunization strategies. While there is a great deal of work dealing with the macroscopic topological properties of the networks, few studies have been devoted to the influence of the community structure. Furthermore, while in many real-world networks communities may overlap, in these studies non-overlapping community structures are considered. In order to gain insight about the influence of the overlapping nodes in the epidemic process we conduct an empirical evaluation of basic deterministic immunization strategies based on the overlapping nodes.…
Study design in causal models
2012
The causal assumptions, the study design and the data are the elements required for scientific inference in empirical research. The research is adequately communicated only if all of these elements and their relations are described precisely. Causal models with design describe the study design and the missing data mechanism together with the causal structure and allow the direct application of causal calculus in the estimation of the causal effects. The flow of the study is visualized by ordering the nodes of the causal diagram in two dimensions by their causal order and the time of the observation. Conclusions whether a causal or observational relationship can be estimated from the collect…
Configurable low-cost plotter device for fabrication of multi-color sub-cellular scale microarrays.
2014
We report on the construction and operation of a low-cost plotter for fabrication of microarrays for multiplexed single-cell analyses. The printing head consists of polymeric pyramidal pens mounted on a rotation stage installed on an aluminium frame. This construction enables printing of microarrays onto glass substrates mounted on a tilt stage, controlled by a Lab-View operated user interface. The plotter can be assembled by typical academic workshops from components of less than 15 000 Euro. The functionality of the instrument is demonstrated by printing DNA microarrays on the area of 0.5 squared centimeters using up to three different oligonucleotides. Typical feature sizes are 5 μm diam…
The comprehensive Open-Dialogue approach in Western Lapland: II. Long-term stability of acute psychosis outcomes in advanced community care
2011
An open dialogue need-adapted approach was applied in Finnish Western Lapland by organizing three-year family therapy training for the entire staff, and by following the outcomes. Three inclusion periods of first-episode psychotic patients were compared. In a two-year follow-up of two consecutive periods during the 1990s (1992–3 and 1994–7) it was found that 81% of patients did not have any residual psychotic symptoms, and that 84% had returned to full-time employment or studies. Only 33% had used neuroleptic medication. A third inclusion period, covering 2003–2005, was organized to determine whether the outcomes were consistent 10 years after the preliminary period. Fewer schizophrenia psy…
The comprehensive Open-Dialogue approach in Western Lapland: I. The incidence of non-affective psychosis and prodromal states
2011
Mental health services in a health district in Finland with a population of 72,000 were developed into a comprehensive family- and network-centered entity by giving all the psychiatric personnel training in family therapy or psychodynamic individual therapy, and by arranging a system in which all psychiatric crises were treated in a family- and network-centered manner by multidisciplinary crisis teams, mostly in the patient’s home. The system is a modification of the Need-Adapted Approach called the Open-Dialogue Approach (ODA). The changes in the incidence of first-contact non-affective psychoses and prodromal states were studied in two cities of the District, considering the five-year per…
Remote sensing and climate data as a key for understanding fasciolosis transmission in the Andes: review and update of an ongoing interdisciplinary p…
2006
Fasciolosis caused by Fasciola hepatica in various South American countries located on the slopes of the Andes has been recognized as an important public health problem. However, the importance of this zoonotic hepatic parasite was neglected until the last decade. Countries such as Peru and Bolivia are considered to be hyperendemic areas for human and animal fasciolosis, and other countries such as Chile, Ecuador, Colombia and Venezuela are also affected. At the beginning of the 1990s a multidisciplinary project was launched with the aim to shed light on the problems related to this parasitic disease in the Northern Bolivian Altiplano. A few years later, a geographic information system (GIS…
Human fascioliasis in Argentina: retrospective overview, critical analysis and baseline for future research
2010
Abstract In Argentina, human fascioliasis has never been adequately analysed, although having a physiography, climate, animal prevalences and lymnaeids similar to those of countries where the disease is endemic such as Bolivia, Peru and Chile. We performed a literature search identifying 58 reports accounting for 619 cases, involving 13 provinces, their majority (97.7%) from high altitudes, in central mountainous areas and Andean valleys, concentrated in Cordoba (430 cases), Catamarca (73), San Luis (29) and Mendoza (28), the remaining provinces being rarely affected. This distribution does not fit that of animal fascioliasis. Certain aspects (higher prevalence in females in a local survey,…