Search results for "PIGMENT"

The Usher syndrome 1G protein SANS participates in the transport of ciliary cargo in photoreceptor cells

2012

Human Usher syndrome (USH) is the most common form of combined deaf-blindness, characterized by profound congenital deafness, constant vestibular dysfunction and pre-pubertal onset of retinitis pigmentosa. The USH1G protein SANS (scaffold protein containing ankyrin repeats and SAM domain) is associated with microtubules and mediates a transport related periciliary protein network in photoreceptor cells. Here we aim to enlighten the involvement of SANS in ciliary transport of photoreceptor cells by identifying proteins associated with SANS in transport complexes. In Y2H screen of retinal cDNA library we identified the direct binding of SANS to dynactin-1 (p150Glued), a subunit of the dynacti…

Lack of antiandrogenic effects of topical bifonazole on sebaceous glands and hairs in the hamster flank organ.

1993

The activity of topically applied bifonazole was evaluated in vivo in the three androgen-dependent structures of the hamster flank organ, i.e. the pigmented spot, sebaceous glands and hairs. Topical bifonazole in our experience did not demonstrate any morphological effect on sebaceous gland and hair even when applied in the dosage of 3 mg/cm<sup>2</sup>/day. On the basis of our morphometric results we can conclude that topically applied bifonazole does not interfere with cutaneous androgen metabolic transformations in the pilosebaceous unit of the flank organ.

A snapshot multi-wavelengths imaging device for in-vivo skin diagnostics

2020

A portable proof-of-concept prototype device for single snapshot capturing of four spectral line images has been designed, assembled and laboratory-tested. It comprises optical unit that ensures even illumination of the skin target area simultaneously at four laser wavelengths - 450 nm, 523 nm, 638 nm and 850 nm, double-camera image recording system, micro-computer managed operation system and a touch-screen display for image control and displaying the concentration distribution maps of four skin chromophores - melanin, oxy-hemoglobin, deoxy-hemoglobin and bilirubin. Besides, the device captures skin auto fluorescence image at 405 nm laser excitation to separate seborrheic keratosis from ot…

Differentiation of seborrheic keratosis from basal cell carcinoma, nevi and melanoma by RGB autofluorescence imaging

2018

A clinical trial on the autofluorescence imaging of skin lesions comprising 16 dermatologically confirmed pigmented nevi, 15 seborrheic keratosis, 2 dysplastic nevi, histologically confirmed 17 basal cell carcinomas and 1 melanoma was performed. The autofluorescence spatial properties of the skin lesions were acquired by smartphone RGB camera under 405 nm LED excitation. The diagnostic criterion is based on the calculation of the mean autofluorescence intensity of the examined lesion in the spectral range of 515 nm–700 nm. The proposed methodology is able to differentiate seborrheic keratosis from basal cell carcinoma, pigmented nevi and melanoma. The sensitivity and specificity of the prop…

Relationships between suspended and sediment organic matter in a semi- enclosed marine system: The Stagnone di Marsala sound (Western Sicily)

1997

To gather information on the interactions between the sediment and suspended organic matter pools in the Stagnone di Marsala, water and sediment samples were collected, on a monthly basis, at 11 stations. Water temperature and salinity showed a clear seasonality whilst particulate and sediment organic matter did not show any clear seasonal pattern. Relative abundances of suspended and sediment organic matter, on the other hand, appeared to be site-dependent and controlled mainly by the dynamic balance between resuspension and sedimentation. High quantities of both suspended and sediment total organic matter were present, while very low algal biomasses (in terms of chlorophyll-a concentratio…

Perpetuum mobile: Latvijas Universitātes fonda mecenātu atbalstīto pētnieku zinātnisko rakstu krājums

2019

Differential response of benthic microbes and meiofauna to fish-farm disturbance in coastal sediments

2001

Bacterial and meiofaunal abundance and biomass and their response to the disturbance induced by fish-farm biodeposition were investigated from March to October 1997 on a monthly basis at two stations of the Gaeta Gulf (Tyrrhenian Sea, Mediterranean Sea). The biopolymeric fraction of the organic matter was characterized by high concentrations which was similar at both fish-farming-impacted and control stations. Similarly, bacteria accounted for a small fraction of the biopolymeric organic carbon (<1%), while the contribution due to auto-fluorescent cell biomass (i.e. prokaryotic and eukaryotic cells displaying auto-fluorescence) to the total biopolymeric carbon was quantitatively negligible …

Seasonal and spatial changes in the sediment organic matter of a semi-enclosed marine system (W-Mediterranean Sea)

1999

The composition of sediment organic matter and the related role of microphytobenthic biomass have been investigated during one-year in a semi-enclosed marine system (Marsala lagoon, Mediterranean Sea). Monthly samples from June 1993 to May 1994 were analysed for carbohydrate, protein, lipid, photosynthetic pigment and total organic matter. The three main biochemical classes of organic compounds (i.e. carbohydrates, proteins and lipids) showed higher concentrations than reported in the literature. However, photosynthetic pigment was quite low, compared to other enclosed marine basins or Mediterranean coastal lagoons. As a result, the contribution of primary organic carbon to the sedimentary …

Ocular Drug Delivery Systems per la veicolazione di molecole bioattive al segmento posteriore dell'occhio

Materiali cementizi fotocatalitici per il rivestimento superficiale di edifici

2009

Innovative cement-based pre-mix products developing photocatalytic activity for surface coating of buildings is a particularly interesting way to improve environmental conditions in urban centres. These products are particularly suited to be used in the historical centres of cities, where, by necessity tied to the movement of people and goods, it is not possible to close the streets to vehicular traffic, so determining a substantially condition of air pollution. The study describes some pre-mix products, containing mineral pigments, the assessment of their photocatalytic activity, using a well-established testing method and shows how the results are influenced by different aging conditions …