Search results for "PIM"
showing 10 items of 3280 documents
Identifying musical pieces from fMRI data using encoding and decoding models.
2018
AbstractEncoding models can reveal and decode neural representations in the visual and semantic domains. However, a thorough understanding of how distributed information in auditory cortices and temporal evolution of music contribute to model performance is still lacking in the musical domain. We measured fMRI responses during naturalistic music listening and constructed a two-stage approach that first mapped musical features in auditory cortices and then decoded novel musical pieces. We then probed the influence of stimuli duration (number of time points) and spatial extent (number of voxels) on decoding accuracy. Our approach revealed a linear increase in accuracy with duration and a poin…
Inhibition of nitric oxide activity by arginine analogs in human renal arteries
2001
Abstract Background: Plasma levels of endogenous guanidine compounds are increased in various pathologic conditions, including chronic renal failure. In the present study we tested the effects of some of these compounds on basal and stimulated nitric oxide activity in human renal arteries. Methods: Rings from human renal arteries were obtained from 22 patients undergoing nephrectomy. The rings were suspended in organ baths for isometric recording of tension. We then studied the effects of N G -monomethyl- l -arginine (L-NMMA), N G , N G -dimethyl- l -arginine (asymmetrical dimethylarginine [ADMA]), aminoguanidine (AG), and methylguanidine (MG) on artery rings under basal and stimulated cond…
Decoding attentional states for neurofeedback Mindfulness vs. wandering thoughts
2018
Abstract Neurofeedback requires a direct translation of neuronal brain activity to sensory input given to the user or subject. However, decoding certain states, e.g., mindfulness or wandering thoughts, from ongoing brain activity remains an unresolved problem. In this study, we used magnetoencephalography (MEG) to acquire brain activity during mindfulness meditation and thought-inducing tasks mimicking wandering thoughts. We used a novel real-time feature extraction to decode the mindfulness, i.e., to discriminate it from the thought-inducing tasks. The key methodological novelty of our approach is usage of MEG power spectra and functional connectivity of independent components as features …
The emergence and adaptive use of prestige in an online social learning task
2020
AbstractPrestige-biased social learning occurs when individuals preferentially learn from others who are highly respected, admired, copied, or attended to in their group. This form of social learning is argued to reflect novel forms of social hierarchy in human societies, and, by providing an efficient short-cut to acquiring adaptive information, underpin the cumulative cultural evolution that has contributed to our species’ ecological success. Despite these potentially important consequences, little empirical work to date has tested the basic predictions of prestige-biased social learning. Here we provide evidence supporting the key predictions that prestige-biased social learning is used …
Tiotropium Respimat® in asthma: a double-blind, randomised, dose-ranging study in adult patients with moderate asthma
2013
Tiotropium, a once-daily long-acting anticholinergic bronchodilator, when administered via Respimat® SoftMist™ inhaler (tiotropium Respimat®) significantly reduces the risk of severe exacerbations and improves lung function in patients with severe persistent asthma that is not fully controlled despite using inhaled corticosteroids (ICS) and long-acting β2-agonists. To further explore the dose–response curve in asthma, we investigated the efficacy and safety of three different doses of tiotropium Respimat® as add-on to ICS in symptomatic patients with moderate persistent asthma. In this randomised, double-blind, placebo-controlled, four-way crossover study, patients were randomised to tiotro…
The Codevelopment of Group Relationships: The Role of Individual Group Member's and Other Group Members' Mutual Influence and Shared Group Environment
2019
Although recent research has provided empirical support for the codevelopment of group interaction (defined as development in a common direction of perceptions of group relationships), no studies have yet investigated the "causes" of codevelopment among group members in the long term. The aim of the current study is to examine how the perceptions of an individual group member, and other group members, regarding group relationships influence each other over the course of treatment. We analyzed group data from 168 adult obese patients who participated in (1 of 20) 12-session therapy groups for weight management. Group relationships were measured by the Group Questionnaire (Krogel et al., 2013…
A hierarchical cluster analysis to determine whether injured runners exhibit similar kinematic gait patterns
2020
Previous studies have suggested that runners can be subgrouped based on homogeneous gait patterns, however, no previous study has assessed the presence of such subgroups in a population of individuals across a wide variety of injuries. Therefore, the purpose of this study was to assess whether distinct subgroups with homogeneous running patterns can be identified among a large group of injured and healthy runners and whether identified subgroups are associated with specific injury location. Three‐dimensional kinematic data from 291 injured and healthy runners, representing both sexes and a wide range of ages (10‐66 years) was clustered using hierarchical cluster analysis. Cluster analysis r…
Passive exposure to speech sounds modifies change detection brain responses in adults
2019
In early life auditory discrimination ability can be enhanced by passive sound exposure. In contrast, in adulthood passive exposure seems to be insufficient to promote discrimination ability, but this has been tested only with a single short exposure session in humans. We tested whether passive exposure to unfamiliar auditory stimuli can result in enhanced cortical discrimination ability and change detection in adult humans, and whether the possible learning effect generalizes to different stimuli. To address these issues, we exposed adult Finnish participants to Chinese lexical tones passively for 2 h per day on 4 consecutive days. Behavioral responses and the brain's event-related potenti…
Decoding Musical Training from Dynamic Processing of Musical Features in the Brain
2018
AbstractPattern recognition on neural activations from naturalistic music listening has been successful at predicting neural responses of listeners from musical features, and vice versa. Inter-subject differences in the decoding accuracies have arisen partly from musical training that has widely recognized structural and functional effects on the brain. We propose and evaluate a decoding approach aimed at predicting the musicianship class of an individual listener from dynamic neural processing of musical features. Whole brain functional magnetic resonance imaging (fMRI) data was acquired from musicians and nonmusicians during listening of three musical pieces from different genres. Six mus…
Instructions for External Focus of Attention Improved Taekwondo Kicking Performance Only Among Less Skilled Youth
2022
External focus of attention (EFA) studies among children have yielded more equivocal results than have those among adults. Some investigators have found an internal focus of attention (IFA) advantage in children and have explained their results by children’s generally lower skill levels, compared to adults. According to the constrained action hypothesis, children’s lower skill levels are not yet associated with over-learned automatic movement patterns, so their motor performance is not disrupted by IFA instructions. In this study, our objective was to examine a possible interaction effect between children’s skill levels and their exposure to either IFA or EFA instructions on motor performa…