Search results for "PIP"
showing 10 items of 1156 documents
CCDC 666841: Experimental Crystal Structure Determination
2008
Related Article: K.Raatikainen, J.Huuskonen, E.Kolehmainen, K.Rissanen|2008|Chem.-Eur.J.|14|3297|doi:10.1002/chem.200701862
CCDC 2068114: Experimental Crystal Structure Determination
2021
Related Article: Shilin Yu, Jas S. Ward, Khai-Nghi Truong, Kari Rissanen|2021|Angew.Chem.,Int.Ed.|60|20739|doi:10.1002/anie.202108126
Marine Indole Alkaloids.
2015
Marine indole alkaloids comprise a large and steadily growing group of secondary metabolites. Their diverse biological activities make many compounds of this class attractive starting points for pharmaceutical development. Several marine-derived indoles were found to possess cytotoxic, antineoplastic, antibacterial and antimicrobial activities, in addition to the action on human enzymes and receptors. The newly isolated indole alkaloids of marine origin since the last comprehensive review in 2003 are reported, and biological aspects will be discussed.
Diversidad liquénica asociada a fenómenos post-incendio en los alcornocales valenciano-castellonenses.
2001
FOS, S., CALATAYUD, A. & BARRENO, E. 2001. Lichen diversity associated with post-fire colonization in the Valenciano-castellonense cork-oak forests. Bot. Complutensis 25: 103113. 103 Simón Fos et al. Diversidad liquénica asociada a fenómenos post-incendio... The post-fire colonization of the burned barks of cork-oaks (Quercus suber L.) by epiphytic lichens affected by fire episodes has been studied in different areas of the Valenciano-castellonense cork-oak forests (Asplenio onopteridis-Querco suberis sigmetum). These forests, which have been affected by fires of different intensity, are located in Espadán and Calderona mountains and in the Desierto de Las Palmas and differ with respect…
Client Applications and Server-Side Docker for Management of RNASeq and/or VariantSeq Workflows and Pipelines of the GPRO Suite
2023
The GPRO suite is an in-progress bioinformatic project for -omics data analysis. As part of the continued growth of this project, we introduce a client- and server-side solution for comparative transcriptomics and analysis of variants. The client-side consists of two Java applications called “RNASeq” and “VariantSeq” to manage pipelines and workflows based on the most common command line interface tools for RNA-seq and Variant-seq analysis, respectively. As such, “RNASeq” and “VariantSeq” are coupled with a Linux server infrastructure (named GPRO Server-Side) that hosts all dependencies of each application (scripts, databases, and command line interface software). Implementation of the Serv…
Central functional response to the novel peptide cannabinoid, hemopressin.
2013
Hemopressin is the first peptide ligand to be described for the CB₁ cannabinoid receptor. Hemopressin acts as an inverse agonist in vivo and can cross the blood-brain barrier to both inhibit appetite and induce antinociception. Despite being highly effective, synthetic CB₁ inverse agonists are limited therapeutically due to unwanted, over dampening of central reward pathways. However, hemopressin appears to have its effect on appetite by affecting satiety rather than reward, suggesting an alternative mode of action which might avoid adverse side effects. Here, to resolve the neuronal circuitry mediating hemopressin's actions, we have combined blood-oxygen-level-dependent, pharmacological-ch…
Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristal…
2007
Cannabinoid-1 (CB1) receptor activation affects gastrointestinal propulsion in vivo. It was our aim to further characterize the involved myenteric mechanisms in vivo and in vitro. In CB1(-/-) mice and wild-type littermates we performed in vivo transit experiments by charcoal feeding and in vitro electrophysiological recordings in mouse small intestinal smooth muscle. Ascending neuronal contraction (ANC) following electrical field stimulation was studied in rat ileum in a partitioned organ bath separating the aboral stimulation site from the oral recording site. The knockout animals displayed an accelerated upper gastrointestinal transit compared to control animals. The CB1 receptor antagoni…
The “central dot sign” in acute epiploic appendagitis
2018
Epiploic appendagitis is the acute inflammation and infarction of epiploic appendages, commonly secondary to torsion. It is a great mimicker as its clinical manifestation may be similar to appendicitis, diverticulitis, or colitis. Focal abdominal pain, tenderness, and mild pyrexia are clinical features of the condition [1]. Epiploic appendages are pedunculated adipose structures which extend from the serosal surface of the colon, along the free taenia and taenia omentalis. They are abundant in the caecum and sigmoid colon and absent in the rectum
Epiphytes and associated fauna on the brown alga Fucus vesiculosus in the Baltic and the North Seas in relation to different abiotic and biotic varia…
2011
Fucus vesiculosus L. is an important habitat-forming macroalga both in the saline and high diverse North Sea and the diluted and low diversity Baltic Sea. Despite its importance, comparisons of the spatial patterns of its epiphytes have rarely been reported. In this study we examined the species composition and density of macro-epiphytes and mobile fauna on the canopy-forming macroalga F. vesiculosus inhabiting different regimes of wave exposure in the North and Baltic Seas. The North and Baltic Seas had distinct epiphyte and mobile faunal communities. Wave exposure and segments of host fronds significantly contributed to the variability in species composition and dominance structure of epi…
gNOMO: a multi-omics pipeline for integrated host and microbiome analysis of non-model organisms
2020
The study of bacterial symbioses has grown exponentially in the recent past. However, existing bioinformatic workflows of microbiome data analysis do commonly not integrate multiple meta-omics levels and are mainly geared toward human microbiomes. Microbiota are better understood when analyzed in their biological context; that is together with their host or environment. Nevertheless, this is a limitation when studying non-model organisms mainly due to the lack of well-annotated sequence references. Here, we present gNOMO, a bioinformatic pipeline that is specifically designed to process and analyze non-model organism samples of up to three meta-omics levels: metagenomics, metatranscriptomic…