Search results for "PIPAC."

showing 6 items of 6 documents

Micromorfologia fogliare comparata ed anatomia generale di Epipactis microphylla (Ehrh.) SW. ed E. helleborine (L.) Crantz (Orchidaceae) in Sicilia

2009

Anatomy strutture Phytodermic SEMarchitettura Leaf.Orchidaceae Epipactis microphylla E. helleborine Flora of Sicily
researchProduct

Pressurized intraperitoneal aerosol chemotherapy with cisplatin and doxorubicin or oxaliplatin for peritoneal metastasis from pancreatic adenocarcino…

2020

Background: Systemic chemotherapy for pancreatic adenocarcinoma (PDAC) and cholangiocarcinoma (CC) with peritoneal metastases (PM) is affected by several pharmacological shortcomings and low clinical efficacy. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is expected to maximize exposure of peritoneal nodules to antiblastic agents. This study aims to evaluate safety and efficacy of PIPAC for PM of PDAC and CC origin. Methods: This is a retrospective analysis of consecutive PDAC and CC cases with PM treated with PIPAC at two European referral centers for peritoneal disease. We prospectively recorded from August 2016 to May 2019 demographic, clinical, surgical, and oncological data…

Peritoneal metastasismedicine.medical_treatmentSettore MED/18 - CHIRURGIA GENERALEpancreatic cancerPIPACcarcinomatosislcsh:RC254-282Pancreatic cancerMedicineDoxorubicincarcinomatosiOriginal ResearchCisplatinChemotherapybusiness.industrySystemic chemotherapyperitoneal metastaseaerosol chemotherapymedicine.diseaselcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensdigestive system diseasesOxaliplatinperitoneal metastasesOncologyCancer researchlocoregional chemotherapyAdenocarcinomaPIPAC.businesscholangiocarcinomamedicine.drugTherapeutic Advances in Medical Oncology
researchProduct

Systemic chemotherapy and pressurized intraperitoneal aerosol chemotherapy (PIPAC): A bidirectional approach for gastric cancer peritoneal metastasis

2019

Abstract Background Few patients affected by gastric cancer peritoneal metastasis (GCPM) are offered locoregional treatment, despite several proof-of-efficacy trials. Pressurized intraperitoneal aerosol chemotherapy (PIPAC) has emerged in recent years as a promising tool to control peritoneal carcinomatosis. The combination of PIPAC with systemic chemotherapy may offer a greater clinical benefit than standard treatment alone. Methods A single-center cohort of 28 consecutive patients affected by GCPM was scheduled for bidirectional treatment, comprising PIPAC and systemic chemotherapy, from September 2017 to September 2019. Data recorded included safety, efficacy and survival outcomes. Ascit…

AdultMalemedicine.medical_specialtyIntraoperative Complicationmedicine.medical_treatmentPopulation03 medical and health sciences0302 clinical medicineStomach NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsmedicinePressureHumansProspective StudieseducationPeritoneal NeoplasmsAgedRetrospective StudiesAerosolseducation.field_of_studyChemotherapyPressurized intraperitoneal aerosol chemotherapy (PIPAC)business.industryStandard treatmentCommon Terminology Criteria for Adverse EventsMiddle AgedPrognosisSurgerySurvival RateOncologyDoxorubicin030220 oncology & carcinogenesisCohortConventional PCIPeritoneal metastasisPeritoneal Cancer Index030211 gastroenterology & hepatologySurgeryFemaleCisplatinbusinessGastric cancerFollow-Up Studies
researchProduct

A new subspecies of Epipactis microphylla (Orchidaceae; Epidendroideae) from Pantelleria Island (Sicily)

2021

A new subspecies of Epipactis microphylla, proposed as subsp. cossyrensis is described and illustrated from Pantelleria, a volcanic island near Sicily. It differs from subsp. microphylla mainly in the shape and size of leaves and bracts and several floral traits. This taxon, previously attributed to E. pollinensis, a species currently treated as a synonym of E. purpurata, grows in the undergrowth of thermophilous woodlands occurring on the top of the island, where it numbers a few tens of individuals. The conservation status, phenology and taxonomic remarks are provided. Keys for the species belonging to the Epipactis atrorubens group (= subsect. Atrorubensae), including E. microphylla, are…

OrchidaceaeOrchid flora of SicilyOrchid taxonomybiologyEndemic orchidsLiliopsidaAsparagalesEpidendroideaeBiodiversityPlant ScienceSubspeciesbiology.organism_classificationNeottieaeTracheophytaNeottieaeTaxonSynonym (taxonomy)BotanyEpipactis atrorubensLimodorinaePlantaeOrchidaceaeEcology Evolution Behavior and SystematicsTaxonomyUndergrowthPhytotaxa
researchProduct

Kaļķaino zāļu purvu veģetācijas sukcesija Engures ezera dabas parkā

2015

Eiropā kaļķainu zāļu purvu platības pēdējā gadsimta laikā ir strauji sarukušas, jo tās netiek atbilstoši apsaimniekotas. Dabiskās sukcesijas gaitā šie biotopi aizaug ar kokiem, krūmiem un graudzālēm. Šī tendence vērojama arī Engures ezera dabas parka kaļķainos zāļu purvos. Viena no dabas parka zāļu purvu lielākajām vērtībām ir augstā orhideju sastopamība. Darba mērķis ir noskaidrot sukcesijas ietekmi uz augu sabiedrībām un orhideju cenopopulācijām. Pētījuma ietvaros aprakstīti 787 veģetācijas parauglaukumi. Biežāk sastopamajām orhideju sugām novērtēta vitalitāte un sastopamība. Dabas parka zāļu purva kvalitāte vērtējama kā vidēja, savukārt orhideju vitalitāte kā zema līdz vidēja, bet sastop…

Epipactis palustrisbiotopu apsaimniekošanakaļķaini zāļu purvidabiskā sukcesijaBioloģijaOphrys insectifera
researchProduct

Systemic chemotherapy and pressurized intraperitoneal aerosol chemotherapy (PIPAC): A case report of a multimodal treatment for peritoneal metastases…

2020

Highlights • Integration of PIPAC to systemic chemotherapy can have good tolerance profile. • Repeated biopsies performed during PIPAC allowed therapy-response monitoring. • Analysis of biopsies performed during PIPAC allowed tailoring of chemotherapy. • Integration of PIPAC to systemic chemotherapy can permit good quality of life.

Oncologymedicine.medical_specialtymedicine.medical_treatmentCase ReportPancreatic ductal adenocarcinoma03 medical and health sciences0302 clinical medicinePharmacokineticsQuality of lifeInternal medicinemedicineMultimodal treatmentAdverse effectChemotherapyPressurized intraperitoneal aerosol chemotherapy (PIPAC)CarcinomatosisSystemic chemotherapybusiness.industryStandard treatmentfungifood and beveragesPeritoneal metastases030220 oncology & carcinogenesisDrug delivery030211 gastroenterology & hepatologySurgerybusinessInternational Journal of Surgery Case Reports
researchProduct