Search results for "PLATE"

The impact of del Nido cardioplegia solution on blood morphology parameters

2021

Background: Crystalloid cardioplegic solutions are believed to reduce hemoglobin significantly and increase the transfusion rate. However, recent reports indicate that the del Nido cardioplegia may preserve blood morphology parameters. Methods: In “The del Nido versus cold blood cardioplegia in aortic valve Replacement” trial patients undergoing aortic valve replacement were randomized into the del Nido (DN) or cold blood cardioplegia (CB) group. For the subanalysis, patients who underwent blood transfusions were excluded from the study. Red blood cell (RBC) count, hemoglobin, white blood cell (WBC) count and platelet (PLT) count were measured before the surgery, 24-, 48-, and 96 hours post…

Abstract TMP17: Revacept, an Inhibitor of Platelet Adhesion in Patients With Symptomatic Carotid Artery Stenosis. Safety Data From the International …

2020

Introduction: Revacept is a novel vascular lesion-directed inhibitor of platelet adhesion and thrombus formation, exhibiting no effects on the homeostatic functions of circulating platelets. Objective: The effects of Revacept on plaque-mediated thrombosis were investigated in patients with symptomatic stenosis of the internal carotid artery (at least 50%, following ECST-criteria). Methods: Within an international, prospective, multicenter (n=16), randomized trial 158 patients could be randomized to receive placebo, or 40/120 mg Revacept by intravenous infusion over 20 minutes. Cerebrovascular events and cardiovascular complications were followed up to 3 months. Results: 158 patients were f…

On reliability of systems with moving material subjected to fracture and instability

2015

Abstract The reliability of systems with moving cracked elastic and isotropic material is considered. The material is modeled as a moving plate which continually has a crack on the edge. The plate is subjected to homogeneous tension acting in the traveling direction and the tension varies temporally around a constant value, the set tension. The tension and the length of the crack are modeled by an Ornstein–Uhlenbeck process and an exponential Ornstein–Uhlenbeck process, respectively. Failure is regarded as the state at which the plate becomes unstable or fractures (or both) and a lower bound for the reliability of the system is derived. Considering reliability of the system leads to first p…

Stochastic analysis of the critical velocity of an axially moving cracked elastic plate

2014

In this study, a probabilistic analysis of the critical velocity for an axially moving cracked elastic and isotropic plate is presented. Axially moving materials are commonly used in modelling of manufacturing processes, like paper making and plastic forming. In such systems, the most serious threats to runnability are instability and material fracture, and finding the critical value of velocity is essential for efficiency. In this paper, a formula for the critical velocity is derived under constraints for the probabilities of instability and fracture. The significance of randomness in different model parameters is investigated for parameter ranges typical of paper material and paper machin…

The Western Alps from the Jurassic to Oligocene: spatio-temporal constraints and evolutionary reconstructions

2005

Abstract Despite extensive research in the last 150 years, the regional tectonic reconstruction of the Western Alps has remained controversial. The curved orogenic belt consists of several ribbon-like continental terranes (Sesia/Austroalpine, Internal Crystalline Massifs, Brianconnais), which are separated by two or more ophiolitic sutures (Piemonte, Valais, Antrona?, Lanzo/Canavese?). High-pressure (HP) metamorphism of each terrane occurred during distinct orogenic episodes: at ∼65 Ma in the Sesia/Austroalpine, at ∼45 Ma in the Piemonte zone and at ∼35 Ma in the Internal Crystalline Massifs. It is suggested that these events reflect individual accretionary episodes, which together with kin…

Pan African plate tectonics and its repercussions on the crust of northeast Africa

1979

Pan African belts of the African mainland and the Arabian-Nubian Shield exhibit evolutionary features which are either compatible with intracontinental ensialic development or with plate margin and Wilson cycle tectonics during the time period ∼ 1100–500 Ma ago.

Tectonic control over large-scale diffuse degassing in eastern Sicily (Italy)

2002

Eastern Sicily (southern Italy) is characterised by the presence of many natural gas emissions (mofettes, mud volcanoes). These gases are mostly carbon dioxide and methane, with minor amounts of helium, hydrogen, carbon monoxide and hydrocarbons. In this study, the extent and orientation of soil gas anomalies (He and CO2) were investigated on a wide area (approximately 110 km2) located just SW of Mt. Etna. From a structural point of view, this area lays on a typical foredeep–foreland system that marks the boundary between the southern part of the Eurasian plate and the northern part of the African plate in the central Mediterranean. No tectonic structure was revealed in this area by surface…

A method for screening diacetyl and acetoin-producing bacteria on agar plates

1994

A simple method for screening bacteria for diacetyl and acetoin production was developed. This method is based on the ability of diacetyl and acetoin to form a red insoluble complex with α-naphthol in the presence of creatine. Addition of carboxymethyl-cellulose containing calcium citrate in the medium allowed discrimination between citrate utilizing and non-utilizing bacteria.

Platelets, eicosanoids and aging.

1992

Oxidative Stress and Mitochondrial Damage in Neurodegenerative Diseases: From Molecular Mechanisms to Targeted Therapies

2020

The progression of Alzheimer's dementia is associated with neurovasculature impairment, which includes inflammation, microthromboses, and reduced cerebral blood flow. Here, we investigate the effects of β amyloid peptides on the function of platelets, the cells driving haemostasis. Amyloid peptide β1-42 (Aβ1-42), Aβ1-40, and Aβ25-35 were tested in static adhesion experiments, and it was found that platelets preferentially adhere to Aβ1-42 compared to other Aβ peptides. In addition, significant platelet spreading was observed over Aβ1-42, while Aβ1-40, Aβ25-35, and the scAβ1-42 control did not seem to induce any platelet spreading, which suggested that only Aβ1-42 activates platelet signalli…