Search results for "PLIF"

showing 10 items of 835 documents

Loss of a novel tumor suppressor gene locus at chromosome 8p is associated with leukemic mantle cell lymphoma

2001

Abstract Patients with mantle cell lymphoma (MCL) may present with either nodal or leukemic disease. The molecular determinants underlying this different biologic behavior are not known. This study compared the pattern of genetic abnormalities in patients with nodal and leukemic phases of MCL using comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH) for specific gene loci. Although both leukemic and nodal MCL showed similar genomic patterns of losses (involving 6q, 11q22-q23, 13q14, and 17p13) and gains (affecting 3q and 8q), genomic loss of chromosome 8p occurred more frequently in patients with leukemic disease (79% versus 11%,P < .001). Subsequent…

medicine.medical_specialtyTumor suppressor geneImmunologyGenes mycLocus (genetics)Lymphoma Mantle-CellBiologyBiochemistryMYC Gene AmplificationGene duplicationmedicineHumansGenes Tumor SuppressorIn Situ Hybridizationmedicine.diagnostic_testGene AmplificationCytogeneticsNucleic Acid HybridizationCell BiologyHematologyPrognosismedicine.diseaseCancer researchMantle cell lymphomaGene DeletionChromosomes Human Pair 8Fluorescence in situ hybridizationComparative genomic hybridizationBlood
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Impacto del miRNA-200c sobre el mecanismo de migración celular en el glioblastoma.Relación con los patrones de amplificación de EGFR.

2016

El Glioblastoma Multiforme (GB), la neoplasia primaria del SNC más importante en adultos, por su frecuencia y agresividad, se muestra como paradigmática de los procesos de infiltración y angiogénesis en las neoplasias. Su localización en el sistema nerviosos central, su alta capacidad invasiva y las consecuencias de una angiogénesis displasica hacen del GB una enfermedad neoplásicas altamente invalidante y de evolución fatal, en la que las distintas acciones terapéuticas se muestran ineficaces. Este trabajo realiza un estudio clínico, morfológico ,genético y epigenético de 46 casos de GB primarios. Se describe un grupo de miRNAs no descritos anteriormente en el GB. Se estableció la correlac…

migraciónmirna-200cglioblastomaamplificación egfr
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"Table 39" of "Measurements of Higgs boson properties in the diphoton decay channel with 36 fb$^{-1}$ of $pp$ collision data at $\sqrt{s} = 13$ TeV w…

2019

Best-fit values and uncertainties of the simplified template cross sections times branching ratio.

minimal mergingP P --> HIGGS < GAMMA GAMMA > X13000.0diphotonssimplified template cross sectionSIGproduction modeHiggs
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Multiplex Ligation-dependent Probe Amplification (MLPA)

2011

The Multiplex Ligation-dependent Probe Amplification (MLPA) is a PCR-based method. The procedure relies on sequence-specific probe hybridization of genomic DNA, followed by multiplex-PCR amplification of the hybridized probe and a semiquantitative analysis of the resulting PCR products. MLPA allows the analysis of around 40 loci in the same reaction, and is a sensitive and relatively fast technique. Only a small amount of DNA is required and results are available within 2 days.The critical factors when performing MLPA analyses from formalin-fixed paraffin-embedded (FFPE) tissues are DNA integrity and purity; for this reason, a suitable DNA extraction method must be chosen.The MLPA protocol …

musculoskeletal diseasescongenital hereditary and neonatal diseases and abnormalitieschemistry.chemical_compoundgenomic DNAchemistryHybridization probeCritical factorsPcr cloningMultiplexComputational biologyMultiplex ligation-dependent probe amplificationDNA extractionDNA
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Optoelectronic devices based on caesium lead halide perovskite nanocrystals

2020

Tradicionalmente, la implementación de materiales activos en circuitos fotónicos integrados se ha basado en la utilización de semiconductores III-V y vidrios y materiales ferroeléctricos dopados con iones de tierras raras. Sin embargo, en la actualidad existe una alternativa basada en (nano) materiales sintetizados por técnicas de química coloidal. La posibilidad de procesar nanomateriales en solución permite fabricar semiconductores con propiedades ópticas (emisión, absorción, dispersión de luz) que pueden diseñarse durante la síntesis. Además, su naturaleza coloidal permite integrarlas en cualquier arquitectura óptica mediante sencillas técnicas de impresión en tinta. En este contexto, lo…

nanotechnologyperovskite nanocrystalsoptoelectronicsHollow-core fibersUNESCO::FÍSICAIntegrated opticsperovskite materialscharge transportamplified spontaneous emissionlead halide perovskitesphoton recycling:FÍSICA [UNESCO]optical gain
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Machine Learning Models for Measuring Syntax Complexity of English Text

2019

In this paper we propose a methodology to assess the syntax complexity of a sentence representing it as sequence of parts-of-speech and comparing Recurrent Neural Networks and Support Vector Machine. We have carried out experiments in English language which are compared with previous results obtained for the Italian one.

naturallanguage-processingText simplificationComputer science02 engineering and technologyEnglish languagecomputer.software_genredeep-learningtext-simplification03 medical and health sciences0302 clinical medicinetext-evaluation0202 electrical engineering electronic engineering information engineeringText-simplification Deep-learning Machine-learningSequenceSyntax (programming languages)Settore INF/01 - Informaticabusiness.industryDeep learningSupport vector machineRecurrent neural network020201 artificial intelligence & image processingArtificial intelligencebusinesscomputer030217 neurology & neurosurgerySentenceNatural language processing
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Oltre i testi unici verso la neocodificazione

2008

Il saggio, partendo dall''analisi delle ragioni sottese alla semplificazione normativa, mette in luce i profili evolutivi che conducono dai testi unici alla neocodificazione.

neocodificazione.semplificazione normativa
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Noiseless Quantum Measurement and Squeezing of Microwave Fields Utilizing Mechanical Vibrations

2017

A process which strongly amplifies both quadrature amplitudes of an oscillatory signal necessarily adds noise. Alternatively, if the information in one quadrature is lost in phase-sensitive amplification, it is possible to completely reconstruct the other quadrature. Here we demonstrate such a nearly perfect phase-sensitive measurement using a cavity optomechanical scheme, characterized by an extremely small noise less than 0.2 quanta. We also observe microwave radiation strongly squeezed by 8 dB below vacuum. A source of bright squeezed microwaves opens up applications in manipulations of quantum systems, and noiseless amplification can be used even at modest cryogenic temperatures.

noiseFOS: Physical sciencesGeneral Physics and AstronomyQuantum measurement02 engineering and technology01 natural sciencesOpticsMesoscale and Nanoscale Physics (cond-mat.mes-hall)0103 physical sciences010306 general physicsQuantumPhysicsQuantum PhysicsCondensed Matter - Mesoscale and Nanoscale Physicsta114business.industrymittausnoiseless amplifications021001 nanoscience & nanotechnologymeluQuadrature (astronomy)VibrationAmplitudequantum systemsmeasurementQuantum Physics (quant-ph)0210 nano-technologybusinesscryogenic temperaturesMicrowave
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Modification of a commercial atomic force microscopy for low-noise, high-resolution frequency-modulation imaging in liquid environment.

2011

A key issue for high-resolution frequency-modulation atomic force microscopy imaging in liquids is minimizing the frequency noise, which requires a detailed analysis of the corresponding noise contributions. In this paper, we present a detailed description for modifying a commercial atomic force microscope (Bruker MultiMode V with Nanoscope V controller), aiming at atomic-resolution frequency-modulation imaging in ambient and in liquid environment. Care was taken to maintain the AFMs original stability and ease of operation. The new system builds upon an optimized light source, a new photodiode and an entirely new amplifier. Moreover, we introduce a home-built liquid cell and sample holder …

noiseMaterials scienceoptical sensorsAtomic force acoustic microscopy530Noise (electronics)law.inventionOpticsphotodiodeslawInstrumentationAtomic de Broglie microscopeatomic force microscopycalcium compoundsbusiness.industrysample holdersAmplifierNoise spectral densityPhotodiodefrequency modulationmodulationfrequencyamplifiersbusinessNon-contact atomic force microscopyFrequency modulationimage resolutionThe Review of scientific instruments
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Simultaneous polarization attraction and Raman amplification of a light beam in optical fibers

2012

International audience; In this paper, we demonstrate that it is possible to combine both Raman amplification and polarization attraction of a signal wave in a single optical fiber by means of a counterpropagating scheme. Experiments were performed near 1550 nm in a continuous wave regime and by means of a 10 Gbit ∕ s return-to-zero signal injected in a 20 kmlong low polarization mode dispersion optical fiber. Complete repolarization and 6.7 dB amplification of the signal wave was achieved by injecting a 850 mW, 1480 nm counterpropagating polarized pump wave.

optical fiberRaman amplificationMaterials sciencePhysics::OpticsFOS: Physical sciencesPolarization-maintaining optical fiber02 engineering and technology01 natural sciences010309 optics020210 optoelectronics & photonicsOptics0103 physical sciences0202 electrical engineering electronic engineering information engineeringDispersion-shifted fiberCircular polarizationpolarization[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics][ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]business.industrynonlinear opticsSingle-mode optical fiberStatistical and Nonlinear PhysicsAtomic and Molecular Physics and OpticsOCISCross-polarized wave generationPolarization mode dispersionOptoelectronicsbusinessPhysics - OpticsPhotonic-crystal fiberOptics (physics.optics)
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