Search results for "PMS"
showing 10 items of 64 documents
Rev protein suppression of complex formation between nuclear proteins and rev-responsive element-containing RNA of human immunodeficiency virus-1
1995
The Rev protein from human immunodeficiency virus type 1 (HIV-1) is known to bind Rev responsive element (RRE) sequence of HIV-1 mRNA. This interaction is thought to enhance expression of viral structural proteins but the mechanism for this effect is uncertain. The aim of this study was to investigate (i) whether other cellular proteins also bind to the RRE sequence and (ii) whether binding of cellular proteins to RRE RNA is influenced by Rev protein. Our results revealed that a variety of RNA-protein complexes are formed when in vitro transcribed RRE-containing RNA is incubated with proteins present in HeLa nuclear extracts. The molecular masses of the most prominent bands in RNase protect…
Digital demodulation for fast set-up of sensorless PMSM electrical drives based on magnetic anisotropy
2009
This paper presents a demodulation algorithm applied to the sensorless control of permanent magnet synchronous motors (PMSM). The sensorless control technique reported in this paper is based on the injection of high frequency voltages to the stator so that the motor currents contain information on the rotor position. This information is then extracted by an appropriate demodulation technique. The presented demodulation algorithm is based on spectral analysis of the signal produced by the sensorless control technique because this is fully characterized and presents not ambiguous correlation between current harmonic content and rotor position. The most important feature of the demodulation al…
Unmet needs and gaps in the identification of secondary progression in multiple sclerosis: a Southern Italy healthcare professionals' perspective
2022
Abstract Objective Multiple sclerosis (MS) is a chronic disease with different clinical courses and a tendency to worsening. The relapsing–remitting MS presents acute onset and relapses of neurological symptoms, followed by their remission. This form can convert to secondary progressive MS (SPMS) with irreversible neurological worsening and disability. The identification of signs, symptoms, markers of progression, and strategies to manage MS patients is mandatory to allow early identification of those at higher risk of conversion to SPMS, for prompt intervention to cope with the progression of the disease. Methods A panel of Italian experts from Southern Italy have reviewed the current know…
PPG/ECG Multisite Combo System Based on SiPM Technology
2019
Two versions of a PPG/ECG combined system have been realized and tested. In a first version a multisite system has been equipped by integrating 3 PPG optodes and 3 ECG leads, whereas in another setup a portable version has been carried out. Both versions have been realized by equipping the optical probes with SiPM detectors. SiPM technology is expected to bring relevant advantages in PPG systems and overcome the limitations of physiological information extracted by state of the art PPG, such as poor sensitivity of detectors used for backscattered light detection and motion artifacts seriously affecting the measurements repeatability and pulse waveform stability. This contribution presents t…
Design and Validation of a FPGA-Based HIL Simulator for Minimum Losses Control of a PMSM
2021
This work examines the FPGA programmable logic platforms applied to minimum losses control of a Permanent Magnet Synchronous Motor (PMSM), which represents a flexible solution for the implementation of an advanced digital control algorithm, given their intrinsic parallel structure and the capability to be directly reprogrammable in the field. In particular, design and validation of a FPGA-based Hardware-In-the-Loop (HIL) simulator is proposed, by investigating about data format, quantization and discretization effects and other issues arising during the experimental validation of a controller prototype, in order to reduce the embedded software development cycle and test control systems. The…
In-situ high spatial resolution LA-MC-ICPMS 230Th/U dating enables detection of small-scale age inversions in speleothems
2017
Abstract We present an in-situ method for Th and U isotope measurements by laser ablation multi-collector inductively coupled plasma mass spectrometry (LA-MC-ICPMS) to determine possible age inversions of stalagmites, using a 213 nm Nd:YAG laser connected to an MC-ICPMS. Due to the low ion beam intensity of 230 Th (20–120 counts per second, cps), we carefully optimized the operating parameters to get highest possible ion beam intensities, i.e., laser fluence (25 J cm −2 ), spot size (110 μm), pulse repetition rate (20 Hz), scan speed (4 μm s −1 ), integration time (1000 s), and He and Ar gas flow (∼0.9 L min −1 and ∼0.6 L min −1 respectively). A precision (2 relative standard error, 2RSE) o…
Development of a Fractional PI controller in an FPGA environment for a Robust High-Performance PMSM Electrical Drive
2021
This paper proposes the application of a Fractional Order PI (FOPI) in the speed loop of a high performance PMSM drive to obtain both speed tracking and load rejection performance with a 1-DOF Proportional Integral (PI) controller and 2-DOF Integral Proportional (IP) controller. Hardware validation was implemented in Field Programmable Gate Array on the LabVIEW environment, based on the National Instruments System-on-Module sbRIO-9651 with Xilinx Zynq-7020. Simulation and experimental results are presented to comparing the performance of a PI, IP and FOPI controllers in the speed loop of a Field Oriented Control (FOC) of a Permanent Magnet Synchronous Motor (PMSM).
Creatine kinase is the main target of reactive oxygen species in cardiac myofibrils.
1996
Abstract Reactive oxygen species (ROS) have been reported to alter cardiac myofibrillar function as well as myofibrillar enzymes such as myosin ATPase and creatine kinase (CK). To understand their precise mode and site of action in myofibrils, the effects of the xanthine/xanthine oxidase (X/XO) system or of hydrogen peroxide (H 2 O 2 ) have been studied in the presence and in the absence of phosphocreatine (PCr) in Triton X-100–treated cardiac fibers. We found that xanthine oxidase (XO), with or without xanthine, induced a decrease in maximal Ca 2+ -activated tension. We attributed this effect to the high contaminating proteolytic activity in commercial XO preparations, since it could be p…
Use of hospital and amubutory data in assessment of screnning, follow-up and complications of diabetes mellitus
2017
Diabetes is a priority health target worldwide. Access to conclusive data is equally a priority in order to establish clear objectives and to implement coordinated action. Medico-administrative databases are being used more and more frequently for this purpose. We set out to illustrate and assess the interest of using a French healthcare consumption database to evaluate screening, surveillance and the risk of acute or chronic complications of diabetes in certain at-risk populations. We concluded that early screening for type-2 diabetes in women with a history of gestational diabetes was inadequate. Although a slight improvement occurred following the recommendations published in 2010, one w…
Business model innovation for the SDGs: Towards a performance measurement system
2019
Business model innovation can be a key element for realizing the transformation needed to accomplish the Sustainable Development Goals. However, literature on Sustainable Business Models still lacks quantitative-oriented approaches and tools supporting the implementation and assessment of business model innovations for sustainability. This study proposes an eight-phase performance measurement system supporting organisations in implementing, assessing and managing business model innovations aiming at contributing to the Sustainable Development Goals. The performance measurement system builds upon literature on business model innovation for sustainability, performance measurement and manageme…