Search results for "POINT"
showing 10 items of 4385 documents
TERRESTRIAL LASER SCANNING FOR COASTAL GEOMORPHOLOGIC RESEARCH IN WESTERN GREECE
2012
We used terrestrial laser scanning (TLS) for (i) accurate volume estimations of dislocated boulders moved by high-energy impacts and for (ii) monitoring of annual coastal changes. In this contribution, we present three selected sites in Western Greece that were surveyed during a time span of four years (2008-2011). The Riegl LMS-Z420i laser scanner was used in combination with a precise DGPS system (Topcon HiPer Pro). Each scan position and a further target were recorded for georeferencing and merging of the point clouds. For the annual detection of changes, reference points for the base station of the DGPS system were marked. Our studies show that TLS is capable to accurately estimate volu…
3D RECONSTRUCTION OF THE ROMAN DOMUS IN THE ARCHAEOLOGICAL SITE OF LYLIBAEUM (MARSALA, ITALY)
2019
Abstract. Generally, terrestrial laser scanning surveys involve a rather large number of scans to ensure a high percentage of overlap required for the scan registration phase (target-based or point-based registration, cloud-to-cloud registration). These approaches result in data redundancy that could slow down both the acquisition and post-processing phases. In recent years, the technological evolution in the field of laser scanners has been directed to the development of devices that are able to perform an onsite pre-registration, to optimize the survey procedures and the reliability of the registration of the scan. The paper presents the results achieved during a terrestrial laser scannin…
DIGITAL PHOTOGRAMMETRY, TLS SURVEY and 3D MODELLING for VR and AR APPLICATIONS in CH
2020
Abstract. The world of valorization of Cultural Heritage is even more focused on the virtual representation and reconstructions of digital 3D models of monuments and archaeological sites. In this scenario the quality and the performances offered by the virtual reality (VR) and augmented reality (AR) navigation take primary importance, improving the accessibility of cultural sites where the real access is not allowed for natural conditions or human possibilities. The creation of a virtual environment useful for these purposes requires a specific workflow to follow, combining different strategies in the fields of survey, 3D modelling and virtual navigation. In this work a specific case of stu…
Autonomous hyperspectral UAS photogrammetry for environmental monitoring applications
2014
Abstract. The unmanned airborne system (UAS) remote sensing using lightweight multi- and hyperspectral imaging sensors offer new possibilities for the environmental monitoring applications. Based on the accurate measurements of the way in which the object reflect and emit energy, wide range of affecting variables can be monitored. Condition for reliable applications is reliable and accurate input data. In many applications, installation of geometric and radiometric reference targets in the object area is challenging, for instance, in forest or water areas. On the other hand, UASs are often operated in very poor conditions, under clouds or under variable cloud cover. Our objective is to deve…
Tree species recognition in species rich area using UAV-borne hyperspectral imagery and stereo-photogrammetric point cloud
2017
Abstract. Recognition of tree species and geospatial information of tree species composition is essential for forest management. In this study we test tree species recognition using hyperspectral imagery from VNIR and SWIR camera sensors in combination with 3D photogrammetric canopy surface model based on RGB camera stereo-imagery. An arboretum forest with a high number of tree species was used as a test area. The imagery was acquired from the test area using UAV-borne cameras. Hyperspectral imagery was calibrated for providing a radiometrically corrected reflectance mosaic, which was tested along with the original uncalibrated imagery. Alternative estimators were tested for predicting tree…
Parametric uncertainty or hydrological changes?
2014
Abstract. The model calibration is the way of hydrologists for searching also a physical interpretation of complex interactions acting within a basin. Actually, it can be frequently noticed how model calibration performed on a given time-window may converge to a point in the parameter space that could be distant from another obtainable calibration of the model in the same basin but considering a different time window. Is that again parametric uncertainty or does the trajectory in the parametric space relate about to a slow hydrological basin change? This paper depicts a possible path for detecting changes' signatures in a streamflow time series. In particular, the paper seeks to draw a way …
Tumor lymphocyte immune response to preoperative radiotherapy in locally advanced rectal cancer: The LYMPHOREC study
2017
IF 7.719; International audience; Introduction: Some studies have suggested that baseline tumor-infiltrating-lymphocytes (TILs), such as CD8+ and FoxP3+ T-cells, may be associated with a better prognosis in colorectal cancer. We sought to investigate modulation of the immune response by preoperative radiotherapy (preopRT) and its impact on survival in locally advanced rectal cancer (LARC). Materials & Methods: We analyzed data for 237 patients with LARC who received RT. Density of TILS (CD8+ and FoxP3+) in intraepithelial (iTILs) and stromal compartments (sTILs) were evaluated from surgery pathological specimens and biopsies performed at baseline. The primary endpoint was to assess the impa…
Trial Watch: Adoptively transferred cells for anticancer immunotherapy
2017
IF 7.719; International audience; Immunotherapies aimed at strengthening immune effector responses against malignant cells are growing at exponential rates. Alongside, the impressive benefits obtained by patients with advanced melanoma who received adoptively transferred tumor-infiltrating lymphocytes (TILs) have encouraged the scientific community to pursue adoptive cell transfer (ACT)-based immunotherapy. ACT involves autologous or allogenic effector lymphocytes that are generally obtained from the peripheral blood or resected tumors, expanded and activated ex vivo, and administered to lymphodepleted patients. ACT may be optionally associated with chemo- and/or immunotherapeutics, with th…
Responsiveness to anti-PD-1 and anti-CTLA-4 immune checkpoint blockade in SB28 and GL261 mouse glioma models.
2018
Immune checkpoint blockade (ICB) is currently evaluated in patients with glioblastoma (GBM), based on encouraging clinical data in other cancers, and results from studies with the methylcholanthrene-induced GL261 mouse glioma. In this paper, we describe a novel model faithfully recapitulating some key human GBM characteristics, including low mutational load, a factor reported as a prognostic indicator of ICB response. Consistent with this observation, SB28 is completely resistant to ICB, contrasting with treatment sensitivity of the more highly mutated GL261. Moreover, SB28 shows features of a poorly immunogenic tumor, with low MHC-I expression and modest CD8(+) T-cell infiltration, suggest…
Pathophysiology of ageing, longevity and age related diseases
2007
Abstract On April 18, 2007 an international meeting on Pathophysiology of Ageing, Longevity and Age-Related Diseases was held in Palermo, Italy. Several interesting topics on Cancer, Immunosenescence, Age-related inflammatory diseases and longevity were discussed. In this report we summarize the most important issues. However, ageing must be considered an unavoidable end point of the life history of each individual, nevertheless the increasing knowledge on ageing mechanisms, allows envisaging many different strategies to cope with, and delay it. So, a better understanding of pathophysiology of ageing and age-related disease is essential for giving everybody a reasonable chance for living a …