Search results for "PPAR"

Monitoring biomarkers during preseason preparation period in professional soccer players

2011

Aim. The present study aimed at investigating the effect of a 3-week experimental intervention on biomarkers in professional soccer players during the preseason preparation-period. Methods. Eight participants (age 22.5±2.2 yrs) were enrolled in the study. During the physical preparation period players have attended a training program (51,9 hours) planned by coaches of “Equipe-Sicilia-2009”. Results. At rest, the lipid profile, the creatine kinase (CK), the lactic-acid dehydrogenase (LDH) and the expression of nuclear receptors peroxisome-proliferator-activated receptors (PPAR α/γ) were analyzed before starting and after 3 weeks of training sessions. The plasma level of CK in our samples sho…

Oculista e cefalee

2009

A role for peroxisome proliferator-activated receptor gamma in resveratrol-induced colon cancer cell apoptosis.

2014

Scope Resveratrol may function as a chemopreventive agent. A recent clinical study demonstrates a reduction in tumor cell proliferation in colorectal patients receiving repeated oral ingestion of resveratrol. However, gaps remain in our knowledge of the molecular mechanisms by which resveratrol exerts its chemopreventive effect. We have previously demonstrated that resveratrol induces apoptosis in colon cancer cells and that resveratrol can sensitize chemoresistant colon cancer cells to various drugs. Based on its ability to activate peroxisome proliferator-activated receptor gamma (PPARγ) in colon cancer cells, we sought to determine the implication of this nuclear transcription factor in …

Daidzein has neuroprotective effects through ligand-binding-independent PPARγ activation.

2011

Phytoestrogens are a group of plant-derived compounds that include mainly isoflavones like daidzein. Phytoestrogens prevent neuronal damage and improve outcome in experimental stroke; however, the mechanisms of this neuroprotective action have not been fully elucidated. In this context, it has been postulated that phytoestrogens might activate the peroxisome proliferator-activated receptor-γ (PPARγ), which exerts neuroprotective effects in several settings. The aim of this study was to determine whether the phytoestrogen daidzein elicits beneficial actions in neuronal cells by mechanisms involving activation of PPARγ. Our results show that daidzein (0.05-5 μM) decreases cell death induced b…

AIRWAYS CELLS IN SWIMMERS: A CASE REPORT AND A REVIEW OF THE LITERATURE.

2007

Comparative environmental analysis of soil sampling methods in precision agriculture for lime application in Paraná State, Brazil

2020

Precision agriculture (PA) provides techniques that favour the localized application of inputs allowing their rational use. This makes the PA a potential indicator of reduced operational costs, input volume, and environmental impacts. The objective of this study was to evaluate and compare the environmental effects of three different sampling methods used in PA for the lime application. The first sampling method evaluated was the grid sampling (GS). It was performed at a density of one sample per hectare in a 100×100 m georeferenced grid. The second method was the directed sampling, that was performed after defining the management zones by soil apparent electrical conductivity (ECa) using a…

La malattia glaucomatosa - GDx.

2008

Valutazione della performance fisica e del livello di autonomia personale nel soggetto anziano.

2008

Con l’invecchiamento della popolazione e l’aumento delle patologie croniche, sono necessari interventi mirati a mantenere la salute e contenere i costi sanitari. La performance fisica dell’anziano si riduce con l’età per la normale riduzione della massa e della potenza muscolare, ma l’allenamento di intensità moderata è utile e migliora anche la performance cognitiva. Negli anziani, programmi di riabilitazione e di home care possono essere utili a prevenire le cadute, l’ospedalizzazione ed i ricoveri in casa di riposo. Il test da sforzo è il metodo classico per valutare la performance fisica, ma informazioni complementari e clinicamente importanti sono fornite dal test del cammino dei 6 min…

Anti-inflammatory effects of pre-seasonal Th1-adjuvant vaccine to Parietaria judaica in asthmatics

2011

Nicola Scichilone, Chiara Minaldi, Roberta Santagata, Salvatore Battaglia, Gaetana Camarda, Vincenzo Bellia Dipartimento Biomedico di Medicina Interna e Specialistica (Di.Bi.M.I.S.), Sezione di Pneumologia, University of Palermo, Palermo, ItalyBackground: The ultra-short course pre-seasonal allergy vaccine, containing appropriate allergoids with the adjuvant monophosphoryl lipid A (MPL), may be effective in treating allergic symptoms. Objective: To explore the timing of the immunological responses to the pre-seasonal allergy vaccine.Methods: Four subcutaneous injections of the active product (Pollinex Quattro) were administered to 20 Parietaria-sensitive intermittent asthmatics (M/F: 12/8; …

Exhaled metabolite patterns to identify recent asthma exacerbations

2021

Asthma is a chronic respiratory disease that can lead to exacerbations, defined as acute episodes of worsening respiratory symptoms and lung function. Predicting the occurrence of these exacerbations is an important goal in asthma management. The measurement of exhaled breath by electronic nose (eNose) may allow for the monitoring of clinically unstable asthma and exacerbations. However, data on its ability to perform this is lacking. We aimed to evaluate whether eNose could identify patients that recently had asthma exacerbations. We performed a cross-sectional study, measuring exhaled breath using the SpiroNose in adults with a physician-reported diagnosis of asthma. Patients were randoml…