Search results for "PPD"

DIAGSOL : development of a new functional marker of exposure to herbicides B-triketones in an agricultural soil

2020

Numerous herbicides target an enzyme found not only in weeds but also in « non-target organisms » such as microorganisms. This proof-of-concept study aims to use microbial gene encoding the targeted enzyme or the targeted enzyme itself as a marker for herbicide exposure in soils. The hppd gene and the encoded enzyme (HPPD; 4-hydroxyphenylpyruvate dioxygenase), targeted by B-triketone herbicides, are the subject of this study. In silico analyses reveal that the hppd gene is spread out in all bacterial phyla. Primers specific to this gene were designed. This primer pair is used to measure the abundance, the composition and the diversity of the hppd bacterial community in soil microcosms expos…

Utilisation de la technique du FRAP pour évaluer la fluidité de la membrane plasmique de cellules végétales en suspension

2014

Modulació de l'artritis gotosa per dues molècules inhibidores de la caspasa-1

2020

L’artritis gotosa es una de les malalties articulars més freqüents d’artritis inflamatòria. Es produeix per la deposició d’urat monosòdic (MSU) en les articulacions, donant lloc a episodis aguts d’inflamació, que poden ser persistents i arribar a cronificar-se. La fagocitosi dels cristalls d’MSU pels neutròfils i macròfags genera la producció de ROS i l’activació de l’NFkappaB, alliberant citocines i activant l’NLRP3. Aquest inflamasoma indueix l’activació de la caspasa1 i la consegüent producció de les formes actives IL1beta i IL18. Les calcones són un grup de la família dels flavonoides, que han demostrat propietats antiinflamatòries i antiartrítiques, actuant sobre diverses dianes terapè…

Transportan 10 Induces Perturbation and Pores Formation in Giant Plasma Membrane Vesicles Derived from Cancer Liver Cells

2023

Continuous progress has been made in the development of new molecules for therapeutic purposes. This is driven by the need to address several challenges such as molecular instability and biocompatibility, difficulties in crossing the plasma membrane, and the development of host resistance. In this context, cell-penetrating peptides (CPPs) constitute a promising tool for the development of new therapies due to their intrinsic ability to deliver therapeutic molecules to cells and tissues. These short peptides have gained increasing attention for applications in drug delivery as well as for their antimicrobial and anticancer activity but the general rules regulating the events involved in cell…

DIAGSOL : Développement d’un outil microbien pour évaluer l’exposition des sols agricoles aux herbicides β-tricétones

2018

International audience; En 2011, en France, plus de 2 millions d’hectares de champs de maïs ont été traités avec desherbicides β-tricétones. Qualifiés de « respectueux de l’environnement » en raison d’une efficacité àfaible dose, de récentes études ont démontré un effet transitoire des β-tricétones sur la diversitébactérienne des sols (Romdhane et al., 2016). L’utilisation récurrente des β-tricétones pourrait, àterme, perturber la diversité bactérienne et les fonctions écosystémiques des sols qu’elle soutient.Il est essentiel d’évaluer l’exposition des microorganismes des sols aux β-tricétones.L’enzyme 4-hydroxyphénylpyruvate dioxygénase (4-HPPD), cible de ces herbicides chez les plantesadv…

«Men dere øver på det hjemme?» : realiseringen av det delte oppdragermandat: en fortolkende studie av kommunikativ praksis i barnehagens foreldresamt…

2016

Masteroppgave pedagogikk - Universitetet i Agder 2016 Det primære pedagogiske mandat, hovedansvaret for barnas oppdragelse, ligger hos foreldrene (Evenshaug & Hallen, 1997). Samtidig skal barnehagen i samarbeid med hjemmet «fremme læring og danning som grunnlag for allsidig utvikling» (barnehageloven, 2006, § 1). Denne kvalitative studien belyser hvordan hjem og barnehage i foreldresamtalen kommuniserer angående oppdragelse. Det empiriske materialet består av åtte foreldresamtaler og etterfølgende intervjuer med foreldre. Med utgangspunkt i Habermas’ (1984) teori om kommunikativ handling, fortolker jeg pedagogers og foreldres bruk av strategisk og kommunikativ handling. Videre drøfter jeg h…

Évaluation de la fluidité de la membrane plasmique avec la sonde fluorescente di-4-ANEPPDHQ: Adaptation de la technique de recouvrement de fluorescen…

2011

National audience; Au cours de l’interaction entre plantes et microorganismes, la membrane plasmique joue un rôle essentiel dans l’organisation précoce des mécanismes de réactions de défense mises en place par la plante. L’équipe Dynamique membranaire et réponse aux stress biotiques, de l’UMR Plante-Microbe-Environnement, s’intéresse aux modifications des propriétés du plasmalemme des cellules végétales dans ce type d’interactions. La fluidité membranaire est une de ces propriétés. La technique de retour de fluorescence après photoblanchiment (FRAP), réalisée à l’aide d’un microscope confocal à balayage laser, a été adaptée à l’étude des variations de la fluidité de la membrane plasmique de…

Common mechanisms underlying membrane modifications induced by protein interactions

2022

Toppdommerrollen i fotball : sammenhengen mellom angst og mental tøffhet og toppdommeres subjektive opplevelse av press i norsk fotball

2016

Masteroppgave i idrettsvitenskap - Universitetet i Agder 2016 Mental toughness, anxiety and pressure are well-used terms within sports, even though it can be difficult to understand the meaning of them. The purpose of this study was to examine the relationship between anxiety (cognitive- and somatic anxiety and self-confidence) and mental toughness, and top-class referees’ subjective experience on pressure as a soccer official. 183 top-class referees answered an online questionnaire. Mental toughness was measured by using the SMTQ and anxiety by using the CSAI-2. Of all the referees included in this study, 97.2% had been active footballers themselves, 44.3% had played on a high level. There…

Oppdragelsessyn i endring? : En komparativ studie av populære oppdragelsesbøker utgitt i Norge i perioden 1950-2000

2017

Masteroppgave pedagogikk PED511 - Universitetet i Agder 2017 The topic of this assignment is to study if the view of parenting has changed in Norway. There have been many discussions about parenting and what it entails. This study is limited to popular books that have been released in Norway between 1950 and 2000. The parenting books emphasise different aspects in the children’s upbringing and how that positively affects their development. The primary research question is to examine the views of parenting and its development from four books from the selected period: “Barneoppdragelse” by Lise Østlyngen (1950), “Barn og foreldre: barneoppdragelse i praksis” by Hambro & Moa (1966), “Elsker du…