Search results for "PPRE"
showing 10 items of 2084 documents
Guillain-Barré syndrome after orthotopic liver transplantation: A clinical manifestation of immune reconstitution inflammatory syndrome?
2018
Guillain-Barrè Syndrome, as part of the spectrum of dysimmune neuropathies, is unexpected to occur in immunocompromised hosts. We describe a clinical case of Guillain-Barrè syndrome, occurred a few weeks after a liver transplant, and we postulate that our case would satisfy all requirements to explain this peripheral nervous system complication as a clinical manifestation of an Immune reconstitution inflammatory syndrome. In this setting of liver transplantation, complicated by potentially multiple infective triggers, reduction of immunosuppression and reversal of pathogen-induced immunosuppression, through antimicrobial therapy, may have led to pro-inflammatory response. The pro-inflammato…
T cell–mediated response to SARS‐CoV‐2 in liver transplant recipients with prior COVID‐19
2021
Abstract Whether immunosuppression impairs severe acute respiratory syndrome coronavirus 2‐specific T‐cell‐mediated immunity (SARS‐CoV‐2‐CMI) after liver transplantation (LT) remains unknown. We included 31 LT recipients in whom SARS‐CoV‐2‐CMI was assessed by intracellular cytokine staining (ICS) and interferon (IFN)‐γ FluoroSpot assay after a median of 103 days from COVID‐19 diagnosis. Serum SARS‐CoV‐2 IgG antibodies were measured by ELISA. A control group of non‐transplant immunocompetent patients were matched (1:1 ratio) by age and time from diagnosis. Post‐transplant SARS‐CoV‐2‐CMI was detected by ICS in 90.3% (28/31) of recipients, with higher proportions for IFN‐γ‐producing CD4+ than …
Is COVID‐19 infection more severe in kidney transplant recipients?
2021
International audience; There are no studies which have compared the risk of severe Covid-19 and related mortality between transplant recipients and non-transplant patients. We enrolled two groups of patients hospitalized for Covid-19, i.e., kidney transplant recipients from the French Registry of Solid Organ Transplant (n=306) and a single-center cohort of non-transplant patients (n=795). An analysis was performed among subgroups matched for age and risk factors for severe Covid-19 or mortality. Severe Covid-19 was defined as admission (or transfer) to an intensive care unit, need for mechanical ventilation, or death.Transplant recipients were younger and had more comorbidities compared to…
Per una storia della rappresentanza processuale. L'azione alieno nomine nella dottrina civilistica e canonistica fra XII e XIII secolo
2008
This essay analyzes the origin of judicial representation concept in medieval legal science. The start point is the Bulgarus's letter to Aymeric (1140), commonly considered the first work about trial. Here the representation is not allowed and the only external subject in trial is the advocatus and he gives only auxilium to her client. At the end of XIIth century, result of growth of ordines iudiciarii - specially dedicated to judicial practice - the concept of representation begins to be the object of specific reflection. The ordo 'Olim' by Otto papiensis (1170-80) may be considered the first work that gives solution to the main problem, in order to the consequences of the sentence on a su…
La batteria PML per la misurazione dei profili di memoria di lavoro nei bambini con disturbi di apprendimento.
2011
The Italian Society of Gastroenterology (SIGE) and the Italian Group for the study of Inflammatory Bowel Disease (IG-IBD) Clinical Practice Guideline…
2010
Biological therapies are an important step in the management of Inflammatory Bowel Diseases. In consideration of high cost and safety issues there is the need to have clear recommendations for their use. Despite the American Gastroenterological Association and the European Crohn's and Colitis Organisation have published exhaustive Inflammatory Bowel Disease guidelines, national guidelines may be necessary as cultural values, economical and legal issues may differ between countries. For these reasons the Italian Society of Gastroenterology and the Italian Group for the study of Inflammatory Bowel Disease have decided to elaborate the Italian guidelines on the use of biologics in Inflammatory…
Poly(I:C) and CpG-ODN combined aerosolization to treat lung metastases and counter the immunosuppressive microenvironment.
2015
The immunostimulatory ability of synthetic oligonucleotides containing CpG motifs (CpG-ODN), agonists of Toll-like receptor 9 (TLR9), can be harnessed to promote antitumor immunity by their application at the tumor site to stimulate local activation of innate immunity; however, particularly in the lung, tumor-associated immunosuppression can subvert such antitumor innate immune responses. To locally maintain continuous activation of innate subpopulations while inhibiting immunosuppressive cells, we evaluated aerosol delivery CpG-ODN combined with Poly(I:C), a TLR3 agonist able to convert tumor-supporting macrophages to tumoricidal effectors, in the treatment of B16 melanoma lung metastases …
Perinatalità e migrazione. il metodo narrativo.
2010
L’esperienza della tutorialità nei contesti educativi con adolescenti migranti soli.
2020
L’esperienza della tutorialità, nei processi educativi e formativi di presa in carico dei minori migranti soli o non accompagnati, si presenta come un terreno fertile e, per certi aspetti, nuovo da esplorare. Su questo terreno si trovano a confrontarsi gli educatori e le educatrici che operano nella vasta rete di accoglienza e protezione dei migranti. La recente attenzione verso figure come il tutor/case manager, l’educatore di riferimento o il tutore legale volontario, costituisce un oggetto di indagine privilegiato in cui convergono diversi ambiti del sapere: dalla pedagogia alle scienze dell’educazione, dalla psicologia alle scienze dell’organizzazione. Nella pratica educativa, la tutori…
Il padiglione siciliano all’esposizione di Roma del 1911: dai disegni di Ernesto Basile alla ricostruzione virtuale
2022
A partire dalla rilettura di disegni originali di progetto, rare foto e riproduzioni grafiche d’epoca, il contributo indaga il Padiglione Siciliano, progettato da Ernesto Basile per l’Esposizione di Roma del 1911, attraverso strumenti e metodi della rappresentazione, per giungere alla realizzazione di ricostruzioni tridimensionali digitali che descrivono l’architettura perduta in maniera filologica e quanto più fedele. La prima fase di studio è stata dedicata all’analisi critica delle testimonianze iconografiche rintracciate. La seconda fase ha riguardato il confronto geometrico-dimensionale con le architetture del XII secolo individuate quale riferimento per il progetto di Basile. La terza…