Search results for "PREDICTION"

showing 10 items of 511 documents

Weighted-average least squares estimation of generalized linear models

2018

The weighted-average least squares (WALS) approach, introduced by Magnus et al. (2010) in the context of Gaussian linear models, has been shown to enjoy important advantages over other strictly Bayesian and strictly frequentist model averaging estimators when accounting for problems of uncertainty in the choice of the regressors. In this paper we extend the WALS approach to deal with uncertainty about the specification of the linear predictor in the wider class of generalized linear models (GLMs). We study the large-sample properties of the WALS estimator for GLMs under a local misspecification framework that allows the development of asymptotic model averaging theory. We also investigate t…

Generalized linear modelEconomics and EconometricsGeneralized linear modelsBayesian probabilityGeneralized linear modelSettore SECS-P/05 - EconometriaLinear predictionContext (language use)01 natural sciencesLeast squares010104 statistics & probabilityWALS; Model averaging; Generalized linear models; Monte Carlo; AttritionFrequentist inference0502 economics and businessAttritionEconometricsApplied mathematicsStatistics::Methodology0101 mathematicsMonte Carlo050205 econometrics MathematicsWALSApplied Mathematics05 social sciencesLinear modelEstimatorModel averaging
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Genetic diversity and trait genomic prediction in a pea diversity panel

2014

Background Pea (Pisum sativum L.), a major pulse crop grown for its protein-rich seeds, is an important component of agroecological cropping systems in diverse regions of the world. New breeding challenges imposed by global climate change and new regulations urge pea breeders to undertake more efficient methods of selection and better take advantage of the large genetic diversity present in the Pisum sativum genepool. Diversity studies conducted so far in pea used Simple Sequence Repeat (SSR) and Retrotransposon Based Insertion Polymorphism (RBIP) markers. Recently, SNP marker panels have been developed that will be useful for genetic diversity assessment and marker-assisted selection. Resu…

Genetic Markers0106 biological sciencesGenotype[SDV]Life Sciences [q-bio]Best linear unbiased predictionBiologyPolymorphism Single Nucleotide01 natural sciences03 medical and health sciencesSativumGenetic variationGenetics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyLeast-Squares Analysis030304 developmental biology2. Zero hungerPrincipal Component Analysis0303 health sciencesGenetic diversitybusiness.industryPeasDiscriminant AnalysisGenetic Variationfood and beveragesBayes Theorem15. Life on landMarker-assisted selectionBiotechnologyPhenotype13. Climate actionEvolutionary biologyGenetic marker[SDE]Environmental SciencesLinear ModelsTraitRate of evolutionbusinessGenome PlantMicrosatellite RepeatsResearch Article010606 plant biology & botanyBiotechnology
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Impact of Safety-Related Dose Reductions or Discontinuations on Sustained Virologic Response in HCV-Infected Patients: Results from the GUARD-C Cohor…

2015

Background: Despite the introduction of direct-acting antiviral agents for chronic hepatitis C virus (HCV) infection, peginterferon alfa/ribavirin remains relevant in many resource-constrained settings. The non-randomized GUARD-C cohort investigated baseline predictors of safety-related dose reductions or discontinuations (sr-RD) and their impact on sustained virologic response (SVR) in patients receiving peginterferon alfa/ribavirin in routine practice. Methods: A total of 3181 HCV-mono-infected treatment-naive patients were assigned to 24 or 48 weeks of peginterferon alfa/ribavirin by their physician. Patients were categorized by time-to-first sr-RD (Week 4/12). Detailed analyses of the i…

Genetics and Molecular Biology (all)MaleChronic HepatitisHepacivirusRibavirin/adverse effectsAsthenia/chemically inducedHepacivirusPolyethylene GlycolBiochemistryPolyethylene GlycolsBody Mass IndexChronic Liver Disease0302 clinical medicineNeutropenia/chemically inducedInterferon-alpha/adverse effectsMedicineChroniclcsh:ScienceLiver Diseasesvirus diseasesAntiviral Agents/adverse effectsCohortScience & Technology - Other Topics030211 gastroenterology & hepatologyDrug Therapy CombinationCohort studyHumanmedicine.medical_specialtyAlpha interferonGastroenterology and HepatologyAntiviral AgentsMicrobiologyDose-Response Relationship03 medical and health sciencesPharmacotherapyHepatitis C Chronic/drug therapyDose Prediction MethodsDrug TherapyAnemia/chemically inducedHumansHemoglobinAgedMedicine and health sciencesBiochemistry Genetics and Molecular Biology (all)HepaciviruScience & TechnologyDose-Response Relationship DrugFlaviviruseslcsh:ROrganismsBiology and Life SciencesProteinsmedicine.diseasedigestive system diseaseschemistryAgricultural and Biological Sciences (all)Withholding TreatmentAstheniaImmunologyProportional Hazards Modellcsh:QHuman medicineRNA virusesPhysiologylcsh:MedicinePeginterferon-alfaPolyethylene Glycols/adverse effectsAdult; Aged; Anemia; Antiviral Agents; Asthenia; Cohort Studies; Dose-Response Relationship Drug; Drug Therapy Combination; Female; Hepacivirus; Hepatitis C Chronic; Host-Pathogen Interactions; Humans; Interferon-alpha; Male; Middle Aged; Neutropenia; Outcome Assessment (Health Care); Polyethylene Glycols; Proportional Hazards Models; RNA Viral; Recombinant Proteins; Ribavirin; Withholding Treatment; Agricultural and Biological Sciences (all); Biochemistry Genetics and Molecular Biology (all); Medicine (all)Cohort Studieschemistry.chemical_compoundOutcome Assessment Health CareMedicine and Health Sciences030212 general & internal medicineViralPathology and laboratory medicineMultidisciplinarybiologyHepatitis C virusPharmaceuticsMedicine (all)AnemiaHepatitis CHematologyRecombinant ProteinOutcome Assessment (Health Care)/methodsMiddle AgedMedical microbiologyHepatitis CRecombinant ProteinsHost-Pathogen InteractionMultidisciplinary SciencesPhysiological ParametersResearch DesignCombinationHost-Pathogen InteractionsVirusesRNA ViralFemaleDrugPathogensHost-Pathogen Interactions/drug effectsResearch ArticleAdultNeutropeniaClinical Research DesignResearch and Analysis MethodsOutcome Assessment (Health Care)Internal medicineRibavirinRecombinant Proteins/adverse effectsRNA Viral/bloodAdult; Aged; Anemia; Antiviral Agents; Asthenia; Cohort Studies; Dose-Response Relationship Drug; Drug Therapy Combination; Female; Hepacivirus; Hepatitis C Chronic; Host-Pathogen Interactions; Humans; Interferon-alpha; Male; Middle Aged; Neutropenia; Outcome Assessment (Health Care); Polyethylene Glycols; Proportional Hazards Models; RNA Viral; Recombinant Proteins; Ribavirin; Withholding TreatmentAdult; Aged; Anemia; Antiviral Agents; Asthenia; Cohort Studies; Dose-Response Relationship Drug; Drug Therapy Combination; Female; Hepacivirus; Hepatitis C Chronic; Host-Pathogen Interactions; Humans; Interferon-alpha; Male; Middle Aged; Neutropenia; Outcome Assessment (Health Care); Polyethylene Glycols; Proportional Hazards Models; RNA Viral; Recombinant Proteins; Ribavirin; Withholding Treatment; Medicine (all); Biochemistry Genetics and Molecular Biology (all); Agricultural and Biological Sciences (all)Proportional Hazards ModelsAntiviral Agentbusiness.industryRibavirinBody WeightHepacivirus/drug effectsViral pathogensInterferon-alphaHepatitis C Chronicbiology.organism_classificationHepatitis virusesMicrobial pathogensRNAAdverse EventsCohort StudiebusinessPloS one
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Exploration of Evolutionary Relations between Protein Structures

2008

We describe a new method for the exploration of evolutionary relations between protein structures.

GeneticsProtein structureChemistryProtein domainProtein designProtein function predictionProtein engineeringSupersecondary structureComputational biologyProtein structure predictionProtein tertiary structure
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MAGEMin 1.0.0

2022

MAGEMin is a Gibbs energy minimization solver package, which computes the thermodynamically most stable assemblage for a given bulk rock composition and pressure/temperature condition. It also returns parameters such as melt fraction or density, which can be combined with geodynamic/petrological tools to simulate, for example, the evolving chemistry of a crystallising melt. MAGEMin is written as a parallel C library and uses a combination of linear programming, extended Partitioning Gibbs free Energy and gradient-based local minimization to compute the most stable mineral assemblage. In this, it differs from exisisting approaches which makes it particularly suitable to utilize modern multic…

Geodyanmics couplingGibbs energy minimizerIgneous stable phase prediction
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MAGEMin 1.0.0

2022

MAGEMin is a Gibbs energy minimization solver package, which computes the thermodynamically most stable assemblage for a given bulk rock composition and pressure/temperature condition. It also returns parameters such as melt fraction or density, which can be combined with geodynamic/petrological tools to simulate, for example, the evolving chemistry of a crystallising melt. MAGEMin is written as a parallel C library and uses a combination of linear programming, extended Partitioning Gibbs free Energy and gradient-based local minimization to compute the most stable mineral assemblage. In this, it differs from exisisting approaches which makes it particularly suitable to utilize modern multic…

Geodyanmics couplingGibbs energy minimizerPhysics::GeophysicsIgneous stable phase prediction
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A novel hardware accelerator for the HEVC intra prediction

2015

International audience; A novel hardware accelerator for the High Efficiency Video Coding (HEVC) intra prediction is presented in this paper in order to reduce the computation complexity within this standard and to accelerate the concerned calculations. We propose a new pipelined structure that we called Processing Element (PE) to execute all angular modes, and we repeat it in five paths that our architecture composed of. We present also another structure to carry out the Planar mode. This architecture supports all intra prediction modes for all prediction unit sizes. The synthesis results show that our design can run at 213 MHz for Xilinx Virtex 6 and is capable to process real time 120 10…

HEVC0209 industrial biotechnologyAdderVirtexComputer scienceProcessing element020208 electrical & electronic engineering1080pFPGAs02 engineering and technologyParallel computingIntra prediction[SPI]Engineering Sciences [physics]020901 industrial engineering & automationPlanar0202 electrical engineering electronic engineering information engineering[ SPI ] Engineering Sciences [physics]Hardware accelerationField-programmable gate arrayCoding (social sciences)
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Fully pipelined real time hardware solution for High Efficiency Video Coding (HEVC) intra prediction

2016

International audience; A fully pipelined hardware accelerator for the High Efficiency Video Coding (HEVC) intra prediction is presented in this paper in order to reduce the computation complexity coming with this module and to accelerate the concerned calculations. Two reconfigurable structures are developed in this paper, the first one concerns angular modes and is identified as Processing Element for Angular (PEA) modes, the other is made in order to handle with the Planar mode and is identified as Processing Element for the Planar (PEP) mode. Each structure is repeated in five paths, that our architecture composed of, working in parallel way. This architecture supports all intra predict…

HEVC[ INFO ] Computer Science [cs]Image compressionComputer scienceReal-time processing1080pFPGAs02 engineering and technologyIntra prediction0202 electrical engineering electronic engineering information engineering[INFO]Computer Science [cs]Field-programmable gate arrayVirtexbusiness.industryReconfigurable computing020206 networking & telecommunicationsFrame rateReconfigurable computingHardware and ArchitectureHardware acceleration020201 artificial intelligence & image processingbusinessSoftwareComputer hardwareImage compressionCoding (social sciences)
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A HARDWARE SOLUTION FOR HEVC INTRA PREDICTION LOSSLESS CODING

2015

International audience; The lossless coding mode of the High Efficiency Video Coding (HEVC) main profile that bypasses transform, quantization, and in-loop filters is described. Compared to the HEVC non-lossless coding mode, the HEVC lossless coding mode provides perfect fidelity and an average bit-rate reduction of 3.2%–13.2%. It also significantly outperforms the existing lossless compression solutions, such as JPEG2000 and JPEG-LS for images as well as WinRAR for data archiving. A fully parallel-based solution is presented in this paper in order to reduce processing time and computation complexity resulting from intra prediction. Two higher performance structures are designed to perform …

HEVC[INFO.INFO-TI] Computer Science [cs]/Image Processing [eess.IV][ INFO.INFO-IM ] Computer Science [cs]/Medical Imaginglossless coding[INFO.INFO-TI]Computer Science [cs]/Image Processing [eess.IV][ INFO.INFO-TI ] Computer Science [cs]/Image Processing[INFO.INFO-IM] Computer Science [cs]/Medical Imaging[INFO.INFO-IM]Computer Science [cs]/Medical Imagingparallel computing 1intra predictionFPGA
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Atmospheric and astrophysical neutrinos above 1 TeV interacting in IceCube

2015

The IceCube Neutrino Observatory was designed primarily to search for high-energy (TeV--PeV) neutrinos produced in distant astrophysical objects. A search for $\gtrsim 100$~TeV neutrinos interacting inside the instrumented volume has recently provided evidence for an isotropic flux of such neutrinos. At lower energies, IceCube collects large numbers of neutrinos from the weak decays of mesons in cosmic-ray air showers. Here we present the results of a search for neutrino interactions inside IceCube's instrumented volume between 1~TeV and 1~PeV in 641 days of data taken from 2010--2012, lowering the energy threshold for neutrinos from the southern sky below 10 TeV for the first time, far bel…

HIGH-ENERGY NEUTRINOSNuclear and High Energy PhysicsParticle physicsAMANDAMesonSolar neutrinoAstrophysics::High Energy Astrophysical PhenomenaINDUCED CASCADESFOS: Physical sciencesCosmic rayAstrophysicsFLUX PREDICTIONS01 natural sciencesIceCube Neutrino ObservatoryIceCubeObservatorySEARCH0103 physical sciencesddc:530Blazar010303 astronomy & astrophysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)Physics010308 nuclear & particles physicsHigh Energy Physics::PhenomenologyAstrophysics::Instrumentation and Methods for AstrophysicsASTRONOMYPERFORMANCEBLAZARSPROMPT LEPTONSGAMMA-RAYPhysics and AstronomyHigh Energy Physics::ExperimentNeutrino astronomyNeutrinoAstrophysics - High Energy Astrophysical PhenomenaphysicsPhysical Review D
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