Search results for "PRESSURE"

Pressure-Stabilized Solvates of Xylazine Hydrochloride

2016

High pressure strongly favors the highest-density polymorph Z of active pharmaceutical ingredient 2-(2,6-xylidino)-5,6-dihydro-4H-1,3-thiazine hydrochloride (xylazine hydrochloride, XylHCl) up to about 0.1 GPa only, but still higher pressure destabilizes this structure. Above 0.1 GPa, XylHCl preferentially crystallizes as solvates with CH2Cl2, CHCl3, or (CH3)2CHOH depending on the solvent used. However, when XylHCl·H2O is dissolved in any of these solvents, the high-pressure crystallizations yield the hydrate XylHCl·H2O only. The single crystals of the CH2Cl2, CHCl3, and (CH3)2CHOH solvates could be grown in situ in a diamond anvil cell, which allowed their structure determination from the …

Isobaric Vapor−Liquid Equilibria of the Water + 1-Propanol System at 30, 60, and 100 kPa

1996

Isobaric vapor−liquid equilibria for the water + 1-propanol system are reported at 30, 60, and 100 kPa. The results were found to be thermodynamically consistent according to Van Ness−Byer−Gibbs, Kojima, and Wisniak methods. The system shows a minimum boiling azeotrope, and the azeotropic composition is scarcely shifted with pressure. Results were compared with literature values. The data were correlated with Margules, Van Laar, Wilson, NRTL, and UNIQUAC liquid-phase activity coefficient models.

Vapor–liquid equilibria in the systems 3-methylpentane+methyl 1,1-dimethylethyl ether and 3-methylpentane+methyl 1,1-dimethylpropyl ether at 101.3 kPa

1999

Abstract Pure-component vapor pressure of 3-methylpentane and vapor–liquid equilibrium (VLE) for the binary systems of 3-methylpentane with methyl 1,1-dimethylethyl ether (MTBE) and with methyl 1,1-dimethylpropyl ether (TAME) at 101.3 kPa have been measured. Both systems exhibit small positive deviations from ideality. They can be described as regular solutions and do not present azeotrope. The activity coefficients and boiling points of the solutions were correlated with its composition by Wilson, UNIQUAC, NRTL, and Wisniak–Tamir equations.

Vapor−Liquid Equilibria for the Binary Systems tert-Butyl Alcohol + Toluene, + Isooctane, and + Methylcyclohexane at 101.3 kPa

1998

Vapor-liquid equilibria were measured for binary systems of tert-butyl alcohol with toluene, isooctane, and methylcyclohexane at 101.3 kPa using a recirculating still. Experimental values of the vapor pressure of non-oxygenated pure components have been obtained. The accuracy of experimental measurements was ±0.01 K in temperature, ±0.01 kPa in pressure, and ±0.001 in mole fractions. The results are thermodynamically consistent according to the point-to-point consistency test. The data were correlated with five liquid-phase activity coefficients models (Margules, Van Laar, Wilson, NRTL, UNIQUAC).

Standalone sauna vs exercise followed by sauna on cardiovascular function in non‐naïve sauna users: A comparison of acute effects

2021

Background and aimsSauna bathing and aerobic exercise have each been shown to affect cardiovascular function. However, direct comparisons between standalone sauna bathing and a combination of exercise and sauna on vascular indices remain limited. Therefore, we conducted a cross-over study using matched durations to explore the hemodynamic changes of sauna exposure when compared to a combination of aerobic exercise and sauna exposure.MethodsParticipants (N = 72) with at least one cardiovascular risk factor underwent, on two separate occasions: (a) a 30-minute sauna at 75°C (SAUNA) and (b) the combination of a 15-minute cycling exercise at 75% maximum heart rate followed by 15-minute sauna ex…

Role of microglia in blood pressure and respiratory responses to acute hypoxic exposure in rats

2021

AbstractMicroglia modulate cardiorespiratory activities during chronic hypoxia. It has not been clarified whether microglia are involved in the cardiorespiratory responses to acute hypoxia. Here we investigated this issue by comparing cardiorespiratory responses to two levels of acute hypoxia (13% O2 for 4 min and 7% O2 for 5 min) in conscious unrestrained rats before and after systemic injection of minocycline (MINO), an inhibitor of microglia activation. MINO increased blood pressure but not lung ventilation in the control normoxic condition. Acute hypoxia stimulated cardiorespiratory responses in MINO-untreated rats. MINO failed to significantly affect the magnitude of hypoxia-induced bl…

Changes in Perfusion Pattern of Experimental Tumors Due to Reduction in Arterial Oxygen Partial Pressure

2006

The Small Size and Superficial Location Suggest That Laparoscopic Partial Nephrectomy Is the First Choice for the Treatment of Juxtaglomerular Cell T…

2021

BackgroundJuxtaglomerular cell tumor (JGCT) is a very rare disease, and surgical resection is the only possible way to cure this tumor. Open nephrectomy and partial nephrectomy have been reported to manage JGCTs with excellent results in the previous reviews. Laparoscopic surgery has been popularized in recent years, while critical issues associated with laparoscopic surgical management have been seldom reported. We summarized the JGCTs in our center to discover the optimal surgical management and its anatomic foundation.MethodsIn this retrospective study, we enrolled a total of 14 JGCT patients. All patients received surgeries and were followed up for up to 11 years. We mainly summarized t…

The Effect of Tyramine, Noradrenaline, and Angiotensin on the Blood Pressure in Hypertensive Patients with Aldosteronism and Low Plasma Renin

1970

The reactivity to the pressor action of tyramine, noradrenaline, and angiotensin was determined in 9 patients with hypertension, aldosteronism and low plasma renin concentration (4 patients with solitary adrenal adenomas, 3 patients with nodular adrenal hyperplasia, 2 patients with unknown adrenal status). In 7 patients tests were repeated following unilateral or subtotal adrenalectomy respectively. For comparison, 5 patients with phaeochromocytoma, 10 patients with benign essential hypertension, and 12 normotensive control subjects were studied. — In the hypertensive patients with aldosteronism and low plasma renin, responsiveness to tyramine was significantly reduced. In contrast, pressor…

Blood pressure measurement in children and adolescents : key element in the evaluation of arterial hypertension

2022

Arterial hypertension is the main modifiable risk factor for cardiovascular disease, occupying the first place among the causes of loss of life years adjusted for disability. In recent years, arterial hypertension in children and adolescents has gained ground in cardiovascular medicine thanks to progress made in several areas, fundamentally in pathophysiological and clinical research. Despite the advances that have been made in recent years, the prevention, diagnosis and treatment of high blood pressure in children and adolescents still have room for improvement. In this sense, the correct measurement of blood pressure is especially important, since it includes a series of essential element…