Search results for "PRIMERS"

showing 10 items of 332 documents

Study of polymorphisms in the promoter region of ovine β-lactoglobulin gene and phylogenetic analysis among the Valle del Belice breed and other shee…

2012

The aim of this work was to sequence the promoter region of b-lactoglobulin (BLG) gene in four sheep breeds, in order to identify polymorphisms, infer and analyze haplotypes, and phylogenetic relationship among the Valle del Belice breed and the other three breeds considered as ancestors. Sequencing analysis and alignment of the obtained sequences showed the presence of 36 single nucleotide polymorphisms (SNPs) and one deletion. A total of 22 haplotypes found in ‘‘best’’ reconstruction were inferred considering the 37 polymorphic sites identified. Haplotypes were used for the reconstruction of a phylogenetic tree using the Neighbor-Joining algorithm. The number of polymorphisms identified s…

Molecular Sequence DataSingle-nucleotide polymorphismLactoglobulinsBreedingPolymorphism Single NucleotideNucleotide diversitySettore AGR/17 - Zootecnica Generale E Miglioramento GeneticoSpecies SpecificityGeneticsAnimalsCluster AnalysisPromoter Regions GeneticMolecular BiologyGenePhylogenyDNA PrimersGeneticsGenetic diversitySheepBase SequenceModels GeneticbiologyPhylogenetic treeHaplotypeGenetic VariationSequence Analysis DNAGeneral Medicinebiology.organism_classificationb-Lactoglobulin Polymorphisms Sheep breeds Phylogenetic analysisBreedMilkHaplotypesSardaSequence Alignment
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Phylogenetic relationships of the family Campulidae (Trematoda) based on 18S rRNA sequences

1998

Traditionally, the family Campulidae has been associated either with the family Fasciolidae, parasites of ruminants, or the Acanthocolpidae, parasites of fishes, based on morphological similarities. Since morphology does not seem to resolve clearly the problem of the relationships of campulids, we have used the sequences of the 18S rRNA gene of the campulids Zalophotrema hepaticum, Campula oblonga and Nasitrema globicephalae, the fasciolid Fasciola hepatica, the acanthocolpid Stephanostomum baccatum and the outgroup Schistosoma mansoni to infer a phylogeny. Maximum parsimony and neighbour-joining methods were applied. Both methods indicated that campulids are closer to acanthocolpids than f…

Molecular Sequence DataZoologyHelminth geneticsPolymerase Chain ReactionDigeneaFasciolidaeHost-Parasite InteractionsPhylogeneticsSequence Homology Nucleic AcidRNA Ribosomal 18SAnimalsCluster AnalysisPhylogenyDNA PrimersMammalsBase SequencebiologyPhylogenetic treeFishesSchistosoma mansoniSequence Analysis DNADNA Helminthbiology.organism_classificationMaximum parsimonyInfectious DiseasesSister groupAnimal Science and ZoologyParasitologyTrematodaRNA HelminthEchinostomaSequence AlignmentParasitology
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Multiple overseas dispersal in amphibians

2003

Amphibians are thought to be unable to disperse over ocean barriers because they do not tolerate the osmotic stress of salt water. Their distribution patterns have therefore generally been explained by vicariance biogeography. Here, we present compelling evidence for overseas dispersal of frogs in the Indian Ocean region based on the discovery of two endemic species on Mayotte. This island belongs to the Comoro archipelago, which is entirely volcanic and surrounded by sea depths of more than 3500 m. This constitutes the first observation of endemic amphibians on oceanic islands that did not have any past physical contact to other land masses. The two species of frogs had previously been tho…

MovementBiogeographyMolecular Sequence DataMantellidaeBiologyphylogenyDNA MitochondrialComorosGeneral Biochemistry Genetics and Molecular BiologyEvolution MolecularAmphibiaddc:570MadagascarVicarianceAnimalsIndian OceanPhylogenybiogeographyDNA PrimersGeneral Environmental ScienceLikelihood FunctionsBase SequenceGeographyModels GeneticGeneral Immunology and MicrobiologyEcologySequence Analysis DNAGeneral MedicineSalt waterBiological dispersalAnuraGeneral Agricultural and Biological SciencesResearch Article
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Tetracycline-controlled transgenic targeting from the SCL locus directs conditional expression to erythrocytes, megakaryocytes, granulocytes, and c-k…

2006

The stem cell leukemia gene SCL, also known as TAL-1, encodes a basic helix-loop-helix transcription factor expressed in erythroid, myeloid, megakaryocytic, and hematopoietic stem cells. To be able to make use of the unique tissue-restricted and spatio-temporal expression pattern of the SCL gene, we have generated a knock-in mouse line containing the tTA-2S tetracycline transactivator under the control of SCL regulatory elements. Analysis of this mouse using different tetracycline-dependent reporter strains demonstrated that switchable transgene expression was restricted to erythrocytes, megakaryocytes, granulocytes, and, importantly, to the c-kit-expressing and lineage-negative cell fracti…

MyeloidErythrocytesGenotypeTransgeneImmunologyMice TransgenicBiologyBiochemistryMiceMegakaryocyteGenes Reporterhemic and lymphatic diseasesProto-Oncogene ProteinsmedicineBasic Helix-Loop-Helix Transcription FactorsAnimalsT-Cell Acute Lymphocytic Leukemia Protein 1DNA PrimersRegulation of gene expressionReporter geneBase SequenceCell BiologyHematologyTetracyclineFlow CytometryMolecular biologyRecombinant ProteinsHematopoiesisHaematopoiesisProto-Oncogene Proteins c-kitmedicine.anatomical_structureGene Expression RegulationBone marrowStem cellMegakaryocytesGranulocytesBlood
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β-Aminobutyric Acid Primes an NADPH Oxidase–Dependent Reactive Oxygen Species Production During Grapevine-Triggered Immunity

2010

International audience; The molecular mechanisms underlying the process of priming are poorly understood. In the present study, we investigated the early signaling events triggered by β-aminobutyric acid (BABA), a well-known priming-mediated plant resistance inducer. Our results indicate that, in contrast to oligogalacturonides (OG), BABA does not elicit typical defense-related early signaling events nor defense-gene expression in grapevine. However, in OG-elicited cells pretreated with BABA, production of reactive oxygen species (ROS) and expression of the respiratory-burst oxidase homolog RbohD gene were primed. In response to the causal agent of downy mildew Plasmopara viticola, a strong…

NADPH OXIDASE-DEPENDENTPhytophthora0106 biological sciencesACIDE β-AMINOBUTYRIQUEPhysiologyArabidopsisBiology01 natural sciencesAminobutyric acid03 medical and health sciencesImmunityTobaccoGene expression[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyVitisDNA Primers030304 developmental biologychemistry.chemical_classification0303 health sciencesReactive oxygen speciesOxidase testNADPH oxidaseReverse Transcriptase Polymerase Chain ReactionAminobutyratesNADPH OxidasesHydrogen PeroxideGeneral MedicineKineticsEnzymeBiochemistrychemistryBABAbiology.proteinCalciumSignal transductionReactive Oxygen SpeciesAgronomy and Crop ScienceRESISTANCE010606 plant biology & botanyMolecular Plant-Microbe Interactions®
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Spatio-temporal expression of Prospero is finely tuned to allow the correct development and function of the nervous system in Drosophila melanogaster.

2007

0012-1606 (Print) Comparative Study Journal Article Research Support, Non-U.S. Gov't; Adaptive animal behaviors depend upon the precise development of the nervous system that underlies them. In Drosophila melanogaster, the pan-neural prospero gene (pros), is involved in various aspects of neurogenesis including cell cycle control, axonal outgrowth, neuronal and glial cell differentiation. As these results have been generally obtained with null pros mutants inducing embryonic lethality, the role of pros during later development remains poorly known. Using several pros-Voila (prosV) alleles, that induce multiple developmental and behavioral anomalies in the larva and in adult, we explored the…

Nervous systemDrosophila melanogaster/*embryologyTranscription Factors/genetics/*metabolismNervous SystemPolymerase Chain Reaction0302 clinical medicineMessenger/*metabolismAntenno-maxillary complexNervous System/*embryologyDrosophila ProteinsProtein IsoformsRegulation of gene expressionGenetics0303 health sciencesbiologyProtein Isoforms/genetics/metabolismNeurogenesisGene Expression Regulation DevelopmentalNuclear ProteinsDrosophila Proteins/genetics/*metabolismPhenotypehumanitiesmedicine.anatomical_structureDrosophila melanogasterPhenotypeDrosophilaDrosophila melanogastereducationContext (language use)ProsperoNerve Tissue ProteinsNerve Tissue Proteins/genetics/*metabolism03 medical and health sciencesNuclear Proteins/genetics/*metabolismmedicineIn Situ Nick-End LabelingAnimalsRNA MessengerMolecular Biology030304 developmental biologyDNA PrimersDevelopmental/*physiologyProsperoCell Biologybiology.organism_classificationGlial cell differentiationMitotic activityGlial cellGene Expression RegulationCentral nervous systemNeuronal cellsRNANeuroscience030217 neurology & neurosurgeryDevelopmental BiologyTranscription FactorsDevelopmental biology
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Peptidases specific for proline-containing peptides and their unusual peptide-dependent regulation in Oenococcus oeni

2009

International audience; Growth of the lactic acid bacterium (LAB) Oenococcus oeni, which is involved in malolactic fermentation during the winemaking process, is stimulated by peptides originating from yeast. In this study, we investigated the impact of peptides on O. oeni growth, peptidase activity and the expression of genes encoding the studied peptidases. Low levels of PepN activity and very high levels of PepI activity were observed in O. oeni, whereas levels of PepX activity were intermediate. The level of biosynthesis of these O. oeni peptidases was shown to depend on peptides present in the culture medium. These results were confirmed by transcriptional analyses of putative pep gene…

NitrogenPeptideElectrophoretic Mobility Shift AssayBiologyApplied Microbiology and Biotechnology[ CHIM ] Chemical Sciences03 medical and health scienceschemistry.chemical_compoundBiosynthesisGene expressionMalolactic fermentation[CHIM]Chemical SciencesPromoter Regions GeneticChromatography High Pressure LiquidOenococcus030304 developmental biologyOenococcus oeniDNA Primerschemistry.chemical_classification0303 health sciences030306 microbiologyReverse Transcriptase Polymerase Chain ReactionGeneral MedicineSequence Analysis DNAbiology.organism_classificationYeastEnzymechemistryBiochemistryGene Expression RegulationFermentationBiotechnologyPeptide Hydrolases
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METAGENOMIC ANALYSIS OF PHYTOPHTHORA DIVERSITY IN NURSERIES OF POTTED ORNAMENTAL SPECIES.

2015

The genetic diversity of Phytophthora was investigated in soil and root samples of potted ornamental and fruit tree plants collected in nurseries located in Apulia and Calabria (Southern Italy) using metagenomic approaches based on Phytophthora genus specific primers. PCR amplicons containing the ITS1 region of the rDNA were sequenced using both a conventional cloning and Sanger sequencing approach and a 454 pyrosequencing protocol. All sequences were accurately analyzed with an appropriate software and used as barcode for species identification utilizing a validated ITS database. The cloning/Sanger sequencing approach enabled the identification of nine different Phytophthora taxa (P. nicot…

Nurseries Metagenomic 454 pyrosequencing Phytophthora spp. genus specific primers.Settore AGR/12 - Patologia Vegetale
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Real-time PCR based procedures for detection and quantification of Aspergillus carbonarius in wine grapes

2008

9 pages, 4 tables, 1 figure.

Ochratoxin ATime FactorsFood ContaminationWineBiologyPolymerase Chain ReactionSensitivity and SpecificityMicrobiologyMicrobiologylaw.inventionchemistry.chemical_compoundSpecies SpecificitylawTaqManVitisDNA FungalOchratoxinPolymerase chain reactionDNA PrimersWineMycotoxinChromatographyGene Amplificationfood and beveragesOchratoxin AGeneral MedicineSpores FungalDNA extractiongenomic DNAAspergillusReal-time polymerase chain reactionchemistryConsumer Product SafetyPolyketide synthasePolyketide SynthasesWine grapesReal-time PCRFood ScienceInternational Journal of Food Microbiology
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Synthesis and assembly of virus-like particles of human papillomaviruses type 6 and type 16 in fission yeast Schizosaccharomyces pombe.

1995

AbstractWe have synthesized capsid proteins of human papillomavirus types 6 (HPV 6) and 16 (HPV 16) in fission yeast Schizosaccharomyces pombe and produced virus-like particles (VLP). The capsid proteins were localized in the nucleus by indirect immunofluorescence and cell fractionation analyses. The VLP were produced in both yeast clones synthesizing L1 alone and L1/L2 and purified by sulfato-cellulofine chromatography. Electron microscopic examination showed that these VLP were similar in structure to native HPV particles. Two HPV 16 L1 variants (16 B27L1 and 16 T3L1), isolated from benign cervical samples, produced many more (68- and 14-fold) VLP than the prototype L1 (16 PL1) derived fr…

Oncogene ProteinsImmunoprecipitationvirusesMolecular Sequence DataBiologyVirusSepharoseViral ProteinsCapsidVirologySchizosaccharomycesCloning MolecularPapillomaviridaeDNA PrimersBase SequenceVirionvirus diseasesOncogene Proteins Viralbiology.organism_classificationMolecular biologyYeastRecombinant ProteinsMicroscopy ElectronCapsidSchizosaccharomyces pombeCapsid ProteinsCell fractionationVirology
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