Search results for "PROFILE"

showing 10 items of 915 documents

Acetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (…

2022

Here, we described the synthesis of novel pyrazole-s-triazine derivatives via an easy one-pot procedure for the reaction of β-dicarbonyl compounds (ethylacetoacetate, 5,5-dimethyl-1,3-cyclohexadione or 1,3-cyclohexadionone) with N,N-dimethylformamide dimethylacetal, followed by addition of 2-hydrazinyl-4,6-disubstituted-s-triazine either in ethanol-acetic acid or neat acetic acid to afford a novel pyrazole and pyrazole-fused cycloalkanone systems. The synthetic protocol proved to be efficient, with a shorter reaction time and high chemical yield with broad substrates. The new pyrazolyl-s-triazine derivatives were tested against the following cell lines: MCF-7 (breast cancer); MDA-MB-231 (tr…

kemiallinen synteesiDMF-DMAlääkekemiabioaktiiviset yhdisteetAnticancer profilePharmaceutical ScienceApoptosisOne-pot synthesisheterosykliset yhdisteetPyrazolyl-s-triazineone-pot synthesis; DMF-DMA; pyrazolyl-<i>s</i>-triazine; anticancer profile; EGFR/PI3K/AKT/mTOR; apoptosisinhibiittoritEGFR/PI3K/AKT/mTOR
researchProduct

Asthma-Related Knowledge and Practices among Mothers of Asthmatic Children: A Latent Class Analysis

2022

Mothers&rsquo; knowledge about childhood asthma influences management practices and disease control, but validating knowledge/practice questionnaires is difficult due to the lack of a gold standard. We hypothesized that Latent Class Analysis (LCA) could help identify underlying mother profiles with similar knowledge/practices. A total of 438 mothers of asthmatic children answered a knowledge/practice questionnaire. Using answers to the knowledge/practice questionnaire as manifest variables, LCA identified two classes: Class 1, &ldquo;poor knowledge&rdquo; (33%); Class 2, &ldquo;good knowledge&rdquo; (67%). Classification accuracy was 0.96. Mothers in Class 2 were more likely to be aware of …

knowledgeHealth Toxicology and Mutagenesispractices.Public Health Environmental and Occupational Healthlatent profilesasthmaasthma; children; disease management; knowledge; latent profiles; mothers; practices.mothersPracticeschildrendisease managementLatent Class AnalysisSurveys and QuestionnairesEducational StatusHumansFemaleasthma; children; knowledge; latent profiles; disease management; mothers; practicesChildInternational Journal of Environmental Research and Public Health
researchProduct

Early Cognitive Profiles Predicting Reading and Arithmetic Skills in Grades 1 and 7

2020

The aim of this study was to investigate cognitive profiles composed of skills predicting the overlap between reading and arithmetic in kindergarten (phonological awareness, letter knowledge, rapid automatized naming, and counting sequence knowledge) and the relation of these profiles to reading and arithmetic skills at Grades 1 and 7. A total of four distinct cognitive profiles were identified in an unselected sample of 1,710 children aged 5–6 years: (1) high linguistic and high counting skills (39.2%), (2) low linguistic and low counting skills (25.4%), (3) high counting skills in relation to linguistic skills (15.3%), and (4) low counting skills in relation to linguistic skills (20.1%). …

kognitiiviset taidotmedia_common.quotation_subjectEducationkouluikäisetPhonological awarenessreadingReading (process)cognitive profilesDevelopmental and Educational Psychologymatemaattiset taidot0501 psychology and cognitive sciencesArithmeticRapid automatized namingmedia_commonkomorbiditeettiPoint (typography)4. Education05 social sciencesLinguistic skillsperson-oriented approach050301 educationCognitionSkill developmentarithmeticcomorbidityVariation (linguistics)lukutaitoPsychologykognitiivinen kehitys0503 education050104 developmental & child psychology
researchProduct

A comparison of force-, velocity- and balanced training approach on force-velocity mechanical outputs and vertical jump height – of national level at…

2019

Master's thesis Sports Science ME517 - University of Agder 2019 INTRODUKSJON.Optimalisering av muskulær power-produksjon har blitt vurderttil å være en essensiell del av prestasjon i ulike idretter, men det foreligger lite litteratur på utøvere på nasjonalt nivå. På bakgrunn av dette,er målet med studien å sammenlikne hvilkettreningsprogram (kraftdominert, hastighetsdominert eller balansert) som er mest gunstig for å øke kraft-hastighetsparametre (F0, V0& Pmax)og vertikal hopphøyde. METODE.Trettifem mannlige elite-utøvere ble rekruttert og delt med stratifisert randomisering ut ifraderes kraft-hastighetsprofil inn i tre ulike treningsgrupper(kraftdominert, hastighetsdominert og balansert), …

kraft-hastighetsprofilME517force-velocity profilepowertreningmuskulær powerhopp-prestasjonjump performancepowertrainingmuscular powerVDP::Medisinske Fag: 700::Idrettsmedisinske fag: 850
researchProduct

Adolescents' engagement profiles and their association with academic performance and situational engagement

2020

This study examined adolescents' engagement profiles and their association with situational engagement and academic performance in lower secondary school settings. The data consisted of 301 Grade 7 students from Finland. By utilizing person-oriented approach with Latent Profiling Analysis on subscales capturing students' overall engagement, four subgroups of students with different overall engagement profiles were identified. These profile groups were further analyzed with respect to differences in student background (gender and maternal education), academic performance (GPA, and reading and mathematics tests), and lesson-specific situational engagement. The profile groups showed difference…

latent profile groupsopintomenestyskoulutyöopiskelumotivaatiooverall engagementeducationalakoululaisetsituational engagementsitoutuminenlower secondary school
researchProduct

The Unexpected profile of agricultural innovators: evidence from an empirical study

2020

[EN] Innovation capacity is essential for farmers to remain competitive and overcome the challenges facing Mediterranean agricultural systems. Based on an extensive empirical study, this paper elucidates the common attributes of innovative farmers in the Region of Valencia (Spain). The model presented in this study investigates whether an innovative attitude can be explained by market-entrepreneurial orientation, learning orientation, individual profile traits and farm size. The findings provide insights into how age and experience affect innovation in agricultural smallholdings. The study shows that the most innovative farmers run large farms and have a strong market-entrepreneurial orient…

lcsh:HF1021-1027ECONOMIA APLICADAEconomics and EconometricsGeography Planning and DevelopmentAffect (psychology)Empirical researchOrientationAprenentatgeLearninglcsh:Agriculture (General)Agricultura InnovacionsInnovationlcsh:Environmental sciencesIndustrial organizationlcsh:GE1-350Farmersbusiness.industrylcsh:S1-972Agricultural and Biological Sciences (miscellaneous)lcsh:Commercial geography. Economic geographyLearning orientationAgricultureProfileValenciaBusiness
researchProduct

The Neuroeducation perspective and individual learning specificities. A study

2022

Il secondo dei 7 principi enucleati nella Charte de la LIEN, esito del primo convegno della Ligue Internationale de l’Éducation Nouvelle, svoltosi a Calais nel 1921, esplicita che “L’educazione deve rispettare l’individualità del ragazzo. Questa individualità può svilupparsi solo con una disciplina che lo conduca alla liberazione delle sue energie spirituali”. A distanza di cento anni, gli impulsi metodologici transdisciplinari offerti dalla recentissima Neurodidattica sembrano perfettamente in sintonia con tale affermazione considerando che questa si concentra proprio su una pratica educativa e formativa volta a soddisfare i bisogni intellettuali ed emotivi di bambini e ragazzi nel rispett…

learning profilememorymemorianeurodidatticaprofilo apprenditivoneuroeducationindividuality.individualitàSettore M-PED/03 - Didattica E Pedagogia Speciale
researchProduct

Comparative chemical composition and bioactivity of leaves essential oils from nine Sicilian accessions of Myrtus communis L.

2019

In this study, the essential oils obtained from the leaves of Myrtus communis L. stored in a collection orchard located at the experimental station ‘Orleans’ of the Department of Agricultural and Forest Sciences of the University of Palermo (Italy) were investigated. The essential oils, analysed by gas chromatography–mass spectrometry, revealed the presence of α-pinene, 1,8-cineole, linalool, limonene and myrtenyl acetate as dominant constituents. The neuroprotective effects of M. communis essential oils were investigated by analysing the antioxidant properties and cholinesterases (acetylcholinesterase, AChE, and butyrylcholinesterase, BChE) inhibitory activity. Essential oils from Scopello…

leaveMyrtus communis010405 organic chemistrychemical profileantioxidant activityGeneral ChemistryBiology01 natural scienceslanguage.human_language0104 chemical sciencescholinesterase inhibitory activityMyrtus communis010404 medicinal & biomolecular chemistryHorticulturelanguageMyrtus communis L.OrchardChemical compositionSicilianJournal of Essential Oil Research
researchProduct

Individuality in the Early Number Skill Components Underlying Basic Arithmetic Skills

2018

Early number skills underlie success in basic arithmetic. However, very little is known about the skill profiles among children in preprimary education and how the potential profiles are related to arithmetic development. This longitudinal study of 440 Finnish children in preprimary education (mean age: 75 months) modeled latent performance-level profile groups for the early number skill components that are proposed to be key predictors of arithmetic (symbolic number comparison, mapping, and verbal counting skills). Based on three assessment time points (September, January, and May), four profile groups were found: the poorest-performing (6%), low-performing (16%), near-average-performing (…

low-performing childrenlcsh:Psychologypoorest-performing childrenearly number skill componentslatent profile analysislcsh:BF1-990behavioral disciplines and activitiesarithmeticpreprimary educationFrontiers in Psychology
researchProduct

Individuality in the Early Number Skill Components Underlying Basic Arithmetic Skills.

2018

Early number skills underlie success in basic arithmetic. However, very little is known about the skill profiles among children in preprimary education and how the potential profiles are related to arithmetic development. This longitudinal study of 440 Finnish children in preprimary education (mean age: 75 months) modeled latent performance-level profile groups for the early number skill components that are proposed to be key predictors of arithmetic (symbolic number comparison, mapping, and verbal counting skills). Based on three assessment time points (September, January, and May), four profile groups were found: the poorest-performing (6%), low-performing (16%), near-average-performing (…

low-performing childrenpoorest-performing childrenearly number skill componentslatent profile analysisPsychologybehavioral disciplines and activitiesarithmeticpreprimary educationOriginal ResearchFrontiers in psychology
researchProduct