Search results for "PROGRAM"
showing 10 items of 5938 documents
Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations
2014
European Community Recent years have seen considerable progress in epidemiological and molecular genetic research into environmental and genetic factors in schizophrenia, but methodological uncertainties remain with regard to validating environmental exposures, and the population risk conferred by individual molecular genetic variants is small. There are now also a limited number of studies that have investigated molecular genetic candidate gene-environment interactions (G x E), however, so far, thorough replication of findings is rare and G x E research still faces several conceptual and methodological challenges. in this article, we aim to review these recent developments and illustrate h…
Embedding the Remote Application Control: Visual API for PDA Programming
2009
PDAs are more and more used as advanced adaptive HEI (human-environment interaction) interfaces, thus enabling their users to easily operate applications remotely running in pervasive computing scenarios. Based on a previous implementation, in this paper we discuss the development of a new set of .NET-compliant Application Programming Interfaces to be used within the Visual Studio IDE. Our main goal is to provide programmers with a set of components to be used with the common drag-and-drop operation, in order to embed a remote application control within an application running on the PDA and vice-versa. The interaction relies on ad-hoc communication protocols over a framework devoted to pair…
Pervasive access to MRI bias artifact suppression service on a grid.
2009
Bias artifact corrupts magnetic resonance images in such a way that the image is afflicted by illumination variations. Some of the authors proposed the Exponential Entropy Driven - Homomorphic Unsharp Masking (E2D-HUM) algorithm that corrects this artifact without any a priori hypothesis about the tissues or the Magnetic Resonance image modality. Moreover, E2D-HUM does not care about the body part under examination and does not require any particular training task. People who want to use this algorithm, which is Matlab-based, have to set their own computers in order to execute it. Furthermore, they have to be Matlab-skilled to exploit all the features of the algorithm. In our work we propos…
High sensitivity of northern pike larvae to UV-B but no UV-photoinduced toxicity of retene
2003
In order to investigate whether increased UV-B radiation is a risk factor, a series of acute laboratory experiments was conducted with larval stages of the northern pike (Esox lucius L.), hatching in Nordic waters in May. Further, a comparative investigation on the acute phototoxicity of retene (7-isopropyl-1-methylphenanthrene), a PAH compound recently revealed to posses UV-B-induced phototoxicity in larval coregonids, was conducted with pike larvae. In semi-static experiment, larvae were pre-exposed to retene (3, 9, 30 and 82 microg/g), with relevant controls, for 24 h and then irradiated for 3 h once a day (two consecutive days) with three UV-B doses (CIE-weighted 1.0, 1.8 or 2.7 kJ/m2 p…
Plasmodium falciparumMalaria: Reduction of Endothelial Cell Apoptosis In Vitro
2005
ABSTRACTOrgan failure inPlasmodium falciparummalaria is associated with neutrophil activation and endothelial damage. This study investigates whether neutrophil-induced endothelial damage involves apoptosis and whether it can be prevented by neutralization of neutrophil secretory products. Endothelial cells from human umbilical veins were coincubated with neutrophils from healthy donors and with sera from eight patients withP. falciparummalaria, three patients withP. vivaxmalaria, and three healthy controls. Endothelial apoptosis was demonstrated by terminal deoxynucleotidyltransferase-mediated dUTP-biotin nick end labeling (TUNEL) and annexin V staining. The rate of apoptosis of cells was …
PRINCIPIO ANTIDISCRIMINATORIO Y DETERMINACIÓN DE LA DESVENTAJA
2013
El artículo examina algunos de los límites del derecho antidiscriminatorio en su actual configuración, a partir de las grandes tendencias que le dan soporte desde el punto de vista legislativo y jurisprudencial. El texto plantea una reflexión sobre los principios interpretativos tradicionales y los problemas de incorporación en el juicio de igualdad de estándares de orden explicativo y justificatorio que permitan captar los patrones o estructuras sociales de discriminación e identificar de forma más precisa a los sujetos. A tal efecto propone la ampliación del espectro argumental de la discriminación indirecta y la igualdad material, a través de criterios interpretativos adicionales derivad…
Physical oceanography, sea-bed photographs and videos of benthos from the Weddell Sea taken with remote operated vehicle CHEROKEE during POLARSTERN c…
2010
The marine ecosystem on the eastern shelf of the Antarctic Peninsula was surveyed 5 and 12 years after the climate-induced collapse of the Larsen A and B ice shelves. An impoverished benthic fauna was discovered, that included deep-sea species presumed to be remnants from ice-covered conditions. The current structure of various ecosystem components appears to result from extremely different response rates to the change from an oligotrophic sub-ice-shelf ecosystem to a productive shelf ecosystem. Meiobenthic communities remained impoverished only inside the embayments. On local scales, macro- and mega-epibenthic diversity was generally low, with pioneer species and typical Antarctic megabent…
Consideraciones para la elaboración de unidades didácticas
2013
El desarrollo de las diferentes áreas/materias, tras haber sido planificadas en el currículum a nivel de Centro/Departamento, se concreta en UNIDADES DIDÁCTICAS (o, en el lenguaje más habitual del profesorado, “temas”). La U.D. constituye una unidad de trabajo que parte de unos objetivos didácticos (específicos) frente a los objetivos generales de etapa/área. Además debe contener los contenidos que se van a desarrollar, las competencias básicas que van a trabajarse, el conjunto de actividades que se pondrán en práctica, las decisiones de carácter metodológico, la temporalización prevista y los criterios e instrumentos de evaluación.
Unified Modeling Language
2005
Mature engineering disciplines are generally characterized by accepted methodical standards for describing all relevant artifacts of their subject matter. Such standards not only enable practitioners to collaborate, but they also contribute to the development of the whole discipline. In 1994, Grady Booch, Jim Rumbaugh, and Ivar Jacobson joined together to unify the plethora of existing object-oriented systems engineering approaches at semantic and notation level (Booch, 2002; Fowler, 2004; Rumbaugh, Jacobson, & Booch, 1998). Their effort led to the Unified Modeling Language (UML), a well-known, general-purpose, tool-supported, process-independent, and industry-standardized modeling lang…
Automatic Reengineering in MDA Using Rewriting Logic as Transformation Engine
2005
Legacy systems are information systems that have been developed by means of methods, tools and database management systems that have become obsolete, but they are still being used due to their reliability. As time goes on, the maintenance of this software becomes more complex, expensive and painful. The MOMENT framework supports automatic formal model transformations in MDA. This model transformation approach is based on the algebraic specification of models and benefits from mature term rewriting system technology to perform model transformation using rewriting logic. In this paper, we present how we apply this formal transformation mechanism to recover a legacy relational database, obtain…